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CDN1163, an activator of sarco/endoplasmic reticulum Ca2+ ATPase, up-regulates mitochondrial functions and protects against lipotoxicity in pancreatic β-cells

Background and Purpose: High levels of Ca2+ in the endoplasmic reticulum (ER), established by the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA), are required for protein folding and cell signalling. Excessive ER Ca2+ release or decreased SERCA activity induces unfolded protein accumulation and ER stress in pancreatic β-cells, leading to defective insulin secretion and diabetes. Here we have inve

Sounding Pico

Sounding Pico is an art project focussing on the Pico-neighbourhood in Santa Monica, CA in the USA –developed in collaboration between artist Maj Hasager and composer Ask Kæreby during winter 2018-19. In response to the often-mediated image of a troubled area with opportunities lost, rather than gained, countermeasures have been taken – perhaps most notably by the cultural asset database Culture M

Statistical properties of aftershock rate decay : Implications for the assessment of continuing activity

Aftershock rates seem to follow a power law decay, but the assessment of the aftershock frequency immediately after an earthquake, as well as during the evolution of a seismic excitation remains a demand for the imminent seismic hazard. The purpose of this work is to study the temporal distribution of triggered earthquakes in short time scales following a strong event, and thus a multiple seismic

A homogeneous earthquake catalog for western Turkey and magnitude of completeness determination

A catalog for earthquakes that occurred in western Turkey during the period 1964-2010 is compiled for achieving homogeneity for magnitudes. Data are obtained from the International Seismological Center (ISC), where earthquake magnitudes are reported in different scales and come from a variety of sources. For establishing a common magnitude expression, namely an equivalent moment magnitude Mw*, new

Uncertainty of B-value estimation in connection with magnitude distribution properties of small data sets

We evaluate the efficiency of the maximum likelihood estimator introduced by Aki (1965), using synthetic datasets exhibiting diverse but well defined properties. The deviation of the b-value estimation from its real value is quantified by Monte Carlo simulations as a function of catalogue features and data properties such as the sample size, the magnitude uncertainties distribution, the round-off

EVIDENCE OF PRECURSORY PATTERNS IN AGGREGATED TIME SERIES

We investigate temporal changes in seismic activity observed in the West Corinth Gulfand North-West Peloponnese during 2008 to 2010. Two major earthquake sequencestook place in the area at that time (in 2008 and 2010). Our aim is to analyse Greekseismicity to attempt to confirm the existence or non-existence of seismic precursorsprior to the strongest earthquakes. Perhaps because the area is geolo

Precursory Activity Before Larger Events in Greece Revealed by Aggregated Seismicity Data

We investigate the seismicity rate behaviour in and around Greece during 2009, seeking significant changes in rate preceding larger events. For individual larger events it is difficult to clearly distinguish precursory rate changes from other, possibly unrelated, variations in seismicity. However, when we aggregate seismicity data occurring within a radius of 10 km and in a 50-day window prior to

Protein Shift – How Membrane Technology Can Contribute

Proteins are not only important for our daily diet but also one of the most important food ingredients worldwide. Since the 1970ies membrane processes have established themselves as a key unit operation in protein processing, e.g., in the dairy industry. The recent trend of the protein shift moving consumption of animal-based to plant-based proteins provides new applications for membrane processes

Affirming Catholicism : The formative years of a liberal Anglo-Catholic organisation in the Church of England, circa 1985 to 2000

This thesis is a history of Affirming Catholicism, a liberal Anglo-Catholic organisation within the Church of England, chiefly covering the period circa 1985 to 2000. It examines the rise of Affirming Catholicism, the events that led to its formation, the individuals involved, and the reasons why it came into being. It assesses how Affirming Catholicism’s theological and ecclesiastical identity ev

Fabrication of nanoclay embedded adsorptive electrospun nanofiber membrane for removal of trace organic molecules

This study aims to fabricate nanoclay (NC) embedded polyacrylonitrile (PAN) adsorptive electrospun nanofibers (Ads-ESNs) as high performance membranes for organic micropollutants (OMPs) removal. Ads-ESN were tested using a comprehensive protocol included adsorption in batches (static) and during filtration (dynamic). The filtration performance of Ads-ESNs was tested using gravity driven membrane (

Entrustable professional activities (EPAs) for undergraduate medical education – development and exploration of social validity

Background: The development of entrustable professional activities (EPAs) as a framework for work-based training and assessment in undergraduate medical education has become popular. EPAs are defined as units of a professional activity requiring adequate knowledge, skills, and attitudes, with a recognized output of professional labor, independently executable within a time frame, observable and me

Evaluation and Mapping of Sustainable Water and Wastewater Treatment with Membrane Processes in South Africa and Sweden

Membrane technology is crucial to achieving Sustainable Development Goal No. 6 of clean water and sanitation for all. Despite its numerous benefits, high capital and operating costs pose major challenges. Recent research has focused on sustainable materials as membranes and more effective cleaning regimes to reduce costs and improve membrane lifespan. While South Africa and Sweden have both begun

Influence of dietary fibers and particle size distribution on food rheology

This chapter deals with the rheology of dietary fiber (DF) suspensions and how their microstructural properties influence them. The DFs obtained from selected vegetables, namely, tomato, apple, carrot, potato, parsnip, and yacon are reported. The amount and composition of the soluble/insoluble fiber have been measured for each type of fiber. For the insoluble part, the microstructural properties s