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Microbial metabolites profile during in vitro human colonic fermentation of breakfast menus consumed by Mexican school children

The nutrition transition promotes the development of childhood obesity. Currently, Mexico is affected by this serious public health problem. The nutritional and functional characterization of a whole menu has a number of advantages over the study of single nutrients. Since breakfast is considered the most important meal of the day, this study aimed to evaluate the metabolite profile produced by in

Kazachstania gamospora and Wickerhamomyces subpelliculosus : Two alternative baker's yeasts in the modern bakery

Saccharomyces cerevisiae, the conventional baker's yeast, remains the most domesticated yeast monopolizing the baking industry. Its rapid consumption of sugars and production of CO2 are the most important attributes required to leaven the dough. New research attempts highlight that these attributes are not unique to S. cerevisiae, but also found in several non-conventional yeast species. A small n

Effect of the protein ligand in DMSO reductase studied by computational methods

The DMSO reductase family is the largest and most diverse family of mononuclear molybdenum oxygen-atom-transfer proteins. Their active sites contain a Mo ion coordinated to two molybdopterin ligands, one oxo group in the oxidised state, and one additional, often protein-derived ligand. We have used density-functional theory to evaluate how the fourth ligand (serine, cysteine, selenocysteine, OH−,

The influence of secondary effects on global warming and cost optimization of insulation in the building envelope

The relative environmental impact from the building construction phase is increasing compared to the operation phase for new buildings. Therefore, it is important to consider the complete environmental life cycle of energy improvement measures. Many advanced optimization methods have been developed in recent years to assess building life cycle impact. However, these previous studies have not fully

The effect of stator design on flowrate and velocity fields in a rotor-stator mixer—An experimental investigation

Rotor-stator mixers (RSMs) are available in different designs, e.g. with different number of stator slots and slot dimensions. However, the relationship between stator design and the RSM hydrodynamics is not well understood. Consequently, manufacturers still base design and stator screen recommendations on trial-and-error. This study reports experimental measurements of how the flowrate through th

Seasonal hypoxia was a natural feature of the coastal zone in the Little Belt, Denmark, during the past 8ka

The extent of the hypoxic area in the Baltic Sea has rapidly expanded over the past century. Two previous phases of widespread hypoxia, coinciding with the Holocene Thermal Maximum (HTM; 8–4ka before present; BP) and the Medieval Climate Anomaly (MCA; 2–0.8ka BP), have been identified. Relatively little is known about bottom water redox conditions in the coastal zone of the Baltic Sea during the H

Continuous flow microfluidic separation and processing of rare cells and bioparticles found in blood – A review

Rare cells in blood, such as circulating tumor cells or fetal cells in the maternal circulation, posses a great prognostic or diagnostic value, or for the development of personalized medicine, where the study of rare cells could provide information to more specifically targeted treatments. When conventional cell separation methods, such as flow cytometry or magnetic activated cell sorting, have fa

Ny tid för uroxen

Vad innebär domesticeringen egentligen för en djurart – och vad krävs för att den återigen skulle kunna ses som ”ursprunglig” eller vild? Kan den utdöda uroxen återskapas?

Adaptive heterosubtypic immunity to low pathogenic avian influenza viruses in experimentally infected mallards

Mallards are widely recognized as reservoirs for Influenza A viruses (IAV); however, host factors that might prompt seasonality and trends in subtype diversity of IAV such as adaptive heterosubtypic immunity (HSI) are not well understood. To investigate this, we inoculated mallards with a prevailing H3N8 low pathogenic avian influenza virus (LPAIV) subtype in waterfowl to determine if prior infect

Utilizing social media to disseminate information and engage feedback: Experiences from the lancet commission on global surgery

INTRODUCTION: The Lancet Commission on Global Surgery (LCoGS) aims to address the critical need for surgical care worldwide. To galvanize the global health community, engage key stakeholders, build an inclusive movement, and strengthen the content and impact of the commission, LCoGS launched a Social Media (SM) campaign. This is the first SM Campaign of any Lancet Commission. METHODS: LCoGS Twitte

No evidence for homosubtypic immunity of influenza H3 in Mallards following vaccination in a natural experimental system

The Mallard (Anas platyrhynchos) is an important reservoir species for influenza A viruses (IAV), and in this host, prevalence and virus diversity are high. Studies have demonstrated the presence of homosubtypic immunity, where individuals are unlikely to be reinfected with the same subtype within an autumn season. Further, evidence for heterosubtypic immunity exists, whereby immune responses spec

Students for global oncology: Building a movement for student education and engagement in an emerging field

Program/Project Purpose: Increased recognition of the global cancer burden and inequalities in care and outcomes have led to the growing field of global oncology, focused on strengthening health systems to improve cancer prevention and care. Motivated students and trainees are in need of pathways to approach these challenges. In 2012, Harvard Medical students formed Students for Global Oncology (S

How does sampling methodology influence molecular detection and isolation success in influenza a virus field studies?

Wild waterfowl are important reservoir hosts for influenza A virus (IAV) and a potential source of spillover infections in other hosts, including poultry and swine. The emergence of highly pathogenic avian influenza (HPAI) viruses, such as H5N1 and H5N8, and subsequent spread along migratory flyways prompted the initiation of several programs in Europe, North America, and Africa to monitor circula