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Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in adult psychiatry. A 20-year register study.

Nylander L, Holmqvist M, Gustafson L, Gillberg C. Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in adult psychiatry. A 20-year register study. Nord J Psychiatry 2012;Early Online:1-7 Objective: Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are increasingly recognized in adults. This study aimed to assess trends in diagnostic

Maximal commutative subrings and simplicity of Ore extensions

The aim of this article is to describe necessary and sufficient conditions for simplicity of Ore extension rings, with an emphasis on differential polynomial rings. We show that a differential polynomial ring, R[x;id_R,\delta], is simple if and only if its center is a field and R is \delta-simple. When R is commutative we note that the centralizer of R in R[x;\sigma,\delta] is a maximal commutativ

Phase optimized skeletal mechanisms for engine simulations

Adaptive chemistry is based on the principle that instead of having one comprehensive model describing the entire range of chemical source term space (typically parameters related to temperature, pressure and species concentrations), a set of computationally simpler models are used, each describing a local region (in multidimensional space) or phases (in zero-dimensional space). In this work, an a

Oral iodinated activated charcoal improves lung function in patients with COPD.

The effect of 8 weeks treatment with oral iodinated activated charcoal (IAC) on lung function of patients with moderate chronic obstructive pulmonary disease (COPD) was examined in a double blind randomized placebo controlled parallel group study with 40 patients. In the IAC group, patients showed a statistically significant improvement of FEV1 baseline by 130 ml compared to placebo, corresponding

The added value of hybrid ventilation/perfusion SPECT/CT in patients with stable COPD or apparently healthy smokers. Cancer-suspected CT findings in the lungs are common when hybrid imaging is used

Ventilation/perfusion (V/P) single-photon emission computed tomography (SPECT) is recognized as a diagnostic method with potential beyond the diagnosis of pulmonary embolism. V/P SPECT identifies functional impairment in diseases such as heart failure (HF), pneumonia, and chronic obstructive pulmonary disease (COPD). The development of hybrid SPECT/computed tomography (CT) systems, combining funct

Phenology of two interdependent traits in migratory birds in response to climate change.

In migratory birds, arrival date and hatching date are two key phenological markers that have responded to global warming. A body of knowledge exists relating these traits to evolutionary pressures. In this study, we formalize this knowledge into general mathematical assumptions, and use them in an ecoevolutionary model. In contrast to previous models, this study novelty accounts for both traits-a

Structural insights into aquaporin selectivity and regulation.

Aquaporins have emerged as one of the structurally best-characterized membrane protein families, with fourteen different structures available from a diverse range of organisms. While all aquaporins share the same fold and passive mechanism for water permeation, structural details allow for differences in selectivity and modes of regulation. These details are now the emphasis of aquaporin structura

Development of a novel combined fluorescence and reflectance spectroscopy system for guiding high-grade glioma resections _ Confirmation of capability in lab experiments

Total resection of glioblastoma multiform (GBM), the most common and aggressive malignant brain tumor, is challenging among other things due to difficulty in intraoperative discrimination between normal and residual tumor cells. This project demonstrates the potential of a system based on a combination of autofluorescence and diffuse reflectance spectroscopy to be useful as an intraoperative guidi

Improving the Lot of the Farmer: Development Challenges in Timor-Leste during the Second Decade of Independence

Large segments of the rural Timorese population survive on subsistence farming characterized by simple production methods and low output. Broad-based improvements in Timorese living standards require increased agricultural output. This article discusses what determines agricultural development in Timor-Leste and how such development can be achieved. The main causes of low agricultural output is fo

Dynamic Temperature Simulation in District Heating Systems in Denmark Regarding Pronounced Transient Behaviour

A dynamic performance of district heating systems was analysed with an emphasis on temperature profile distortion throughout a heating system network. Therefore, a modelling approach (the so-called node method) developed at the Technical University of Denmark was applied. For comparison purposes, commercial TERMIS software was also used in this work. Typical supply conditions were investigated in

How to image patients with spine pain.

Different radiological methods play an important role in the work-up of patients complaining of spine pain. Depending on the symptoms and the suspected underlying etiology different methods are selected. In the following presentation we briefly present the different radiological and magnetic resonance tomography methods that are at hand, give some guidance in which method to use, and present the t

Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia.

Protein kinase C (PKC) belongs to a family of ten serine/threonine protein kinases encoded by nine genes. This family of proteins plays critical roles in signal transduction which results in cell proliferation, survival, differentiation and apoptosis. Due to differential subcellular localization and tissue distribution, each member displays distinct signaling characteristics. In this review, we ha

People Living in Community with a Severe Mental Illness: Utilization and Satisfaction with Care and Support.

The object of this paper was to investigate the experiences of patients with severe mental illness (SMI) living in a community, including their utilization of care and treatment services. Psychiatric care and social services staff members were asked to make an inventory of those they served in two districts of Malmö, Sweden. Participants had to be over 18 years of age and unable to manage their da

LRIG1 and the liar paradox in prostate cancer: a study of the expression and clinical significance of LRIG1 in prostate cancer

The course of prostate cancer varies greatly, and additional prognostic markers are needed. Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) is an endogenous inhibitor of growth factor signaling and a proposed tumor suppressor. Publicly available gene expression datasets indicate that LRIG1 may be overexpressed in prostate cancer. In our study, the expression of LRIG1 protein

Detecting EGFR alterations in clinical specimens-pitfalls and necessities.

We investigated the epidermal growth factor receptor (EGFR) status in early stage lung cancer in Southern Sweden, a population for which there are no previous reports on the EGFR mutation frequency. Three hundred fifty small cell lung cancers, adenocarcinomas (AC), squamous cell carcinomas (SqCC), and large cell carcinomas were analyzed using a combination of techniques for the analysis of protein

Soil bacterial and fungal communities across a pH gradient in an arable soil.

Soils collected across a long-term liming experiment (pH 4.0-8.3), in which variation in factors other than pH have been minimized, were used to investigate the direct influence of pH on the abundance and composition of the two major soil microbial taxa, fungi and bacteria. We hypothesized that bacterial communities would be more strongly influenced by pH than fungal communities. To determine the