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Cognitive impairment in rats after long-term exposure to GSM-900 mobile phone radiation
Considering the frequent use of mobile phones, we have directed attention to possible implications on cognitive functions. In this study we investigated in a rat model the long-term effects of protracted exposure to Global System for Mobile Communication-900 MHz (GSM-900) radiation. Out of a total of 56 rats, 32 were exposed for 2 h each week for 55 weeks to radio-frequency electromagnetic radiati
NORdic trial of oral Methylprednisolone as add-on therapy to Interferon beta-1a for treatment of relapsing-remitting Multiple Sclerosis (NORMIMS study): a randomised, placebo-controlled trial
Background Treatment of relapsing-remitting multiple sclerosis with interferon beta is only partly effective, and new more effective and safe strategies are needed. Our aim was to assess the efficacy of oral methylprednisolone as an add-on therapy to subcutaneous interferon beta-1a to reduce the yearly relapse rate in patients with relapsing-remitting multiple sclerosis. Methods NORMIMS (NORdic tr
Implementation of a labeling algorithm based on contour tracing with feature extraction
This paper describes an architecture of a connected-cluster labeling algorithm for binary images based on contour tracing with feature extraction. The implementation is intended as a hardware accelerator in a self contained real-time digital surveillance system. The algorithm has lower memory requirements compared to other labeling techniques and can guarantee labeling of a predefined number of cl
Is Rhizoplaca (Lecanorales, lichenized Ascomycota) a monophyletic genus?
Rhizoplaca Zopf is a genus characterized by an umbilicate thallus with an upper and a lower cortex, as well as a cupulate hypothecium. It has been considered to be related to Lecanora Ach., the type genus of the Lecanoraceae and, in particular, to the lobate species of this genus. The phylogeny of Rhizoplaca, the monotypic Arctopeltis thuleana Poelt, and a number of representatives of different gr
Genetic association of CDC2 with cerebrospinal fluid tau in Alzheimer's disease
We have recently reported that a polymorphism in the cell division cycle (CDC2) gene, designated Ex6 + 7I/D, is associated with Alzheimer's disease (AD). The CDC2 gene is located on chromosome 10q21.1 close to the marker D10S1225 linked to AD. Active cdc2 accumulates in neurons containing neurofibrillary tangles (NFT), a process that can precede the formation of NFT. Therefore, CDC2 is a promising
Risks of Rheumatic Diseases in First- and Second-Generation Immigrants in Sweden
Objective. To examine whether there is an association between country of birth in first-generation immigrants and first hospitalization for a rheumatic disease, and to study whether any such association remains in second-generation immigrants. Methods. In this followup study, the Swedish MigMed database at the Karolinska Institute in Stockholm was used to identify all primary hospital diagnoses of
Quality of life and pain in Parkinson's disease: a controlled cross-sectional study
Purpose. To compare health-related quality of life (HRQL) and-pain symptoms in patients with PD with a matched control group. To our knowledge, controlled studies of Parkinson's disease (PD) patients within this area are rare. Scope. Fifty-seven patients and 95 controls took part in a self-administered questionnaire study. The instruments were the SF-36, visual analogue scales, pain drawing and pa
Cerebral infarction in a girl who developed anticardiolipin syndrome after acute lymphoblastic leukemia
We would like to report a case of cerebral infarction associated with anti-cardiolipin syndrome occurring 8 years after cessation of successful treatment of acute lymphoblastic leukemia and 11 years after cranial irradiation.
Measurement of renal blood flow by magnetic resonance angiography
Localized changes in the structural stability of myoglobin upon adsorption onto silica particles, as studied with hydrogen/deuterium exchange mass spectrometry
A new method is presented for monitoring the conformational stability of various parts of a protein that is physically adsorbed onto nanometer-sized silica particles. The method employs hydrogen/deuterium (H/D) exchange of amide hydrogens, a process that is extremely sensitive to structural features of proteins. The resulting mass increase is analyzed with Fourier transform ion cyclotron resonance
Simple Cystatin C-Based Prediction Equations for Glomerular Filtration Rate Compared with the Modification of Diet in Renal Disease Prediction Equation for Adults and the Schwartz and the Counahan-Barratt Prediction Equations for Children.
BACKGROUND: Serum creatinine is the most commonly used marker for estimation of glomerular filtration rate (GFR). To compensate for its drawbacks as a GFR marker, several prediction equations including several parameters are being used, with the Modification of Diet in Renal Disease (MDRD), Schwartz, and Counahan-Barratt equations being the ones most widely accepted for estimation of relative GFR
The importance of data sampling and analysis in resolving crocodylian relationships.
Abstract not available
Crystallite size of haematite from thermal oxidation of pyrite and marcasite - effects of grain size and iron disulphide polymorph
A study relating the properties of haematite (alpha-Fe2O3) produced by thermal oxidation of pyrite and marcasite (both FeS2) in air for 1 h at temperatures between 200 and 650 degreesC, to the iron disulphide polymorph and grain size of the sample is reported. Comparisons feature crystallite sizes of haematite from pyrite and marcasite oxidation, and the 125-250 and 710-1000 mum fractions. The cry
Increased plasma concentrations of N-terminal pro-B-type natriuretic peptide in patients with mild primary hyperparathyroidism
Objective Primary hyperparathyroidism (PHPT) is associated with heart disease. The aims of the present study were to evaluate how cardiac function and secretion of N-terminal pro-B-type natriuretic peptide (NT-proBNP) correlate in patients with mild PHPT, and how the plasma level of NT-proBNP is influenced by cure of the parathyroid disease. Design and patients Forty-two patients with PHPT without
Structural requirements for Ca2+ binding to the gamma-carboxyglutamic acid and epidermal growth factor-like regions of factor IX. Studies using intact domains isolated from controlled proteolytic digests of bovine factor IX
Blood coagulation factor IX is composed of discrete domains with an NH2-terminal vitamin K-dependent gamma-carboxyglutamic acid (Gla)-containing region, followed by two domains that are homologous with the epidermal growth factor (EGF) precursor and a COOH-terminal serine protease part. Calcium ions bind to the Gla-containing region and to the NH2-terminal EGF-like domain. To be able to determine
MRI with diffusion tensor imaging post-mortem at 3.0 T in a patient with frontotemporal dementia.
Do patients improve in general psychiatric outpatient care? Problem severity among patients and the effectiveness of a psychiatric outpatient unit.
This study evaluated a routine psychiatric outpatient unit that admitted a variety of diagnoses and was staffed with a multi-professional team. The aim was to describe the problem severity among patients of a routine psychiatric outpatient unit in Sweden and to evaluate the statistical and clinical effectiveness of routine care assessed at the termination of treatment. Newly admitted patients were
Aggregation of a Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Copolymer in Aqueous Solution Studied using Rayleigh-Brillouin and Dynamic Light Scattering
Blood Pressure and Risk of Renal Cell Carcinoma in the European Prospective Investigation into Cancer and Nutrition
Elevated blood pressure has been implicated as a risk factor for renal cell carcinoma (RCC), but prospective studies were confined to men and did not consider the effect of antihypertensive medication. The authors examined the relation among blood pressure, antihypertensive medication, and RCC in the European Prospective Investigation into Cancer and Nutrition (EPIC). Blood pressure was measured i
