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Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Distinct tissue-specific mechanisms mediate insulin action in fasting and postprandial states. Previous genetic studies have largely focused on insulin resistance in the fasting state, where hepatic insulin action dominates. Here we studied genetic variants influencing insulin levels measured 2 h after a glucose challenge in >55,000 participants from three ancestry groups. We identified ten new lo

Search for high-mass Wγ and Zγ resonances using hadronic W/Z boson decays from 139 fb −1 of pp collisions at √s = 13 TeV with the ATLAS detector

A search for high-mass charged and neutral bosons decaying to Wγ and Zγ final states is presented in this paper. The analysis uses a data sample of s = 13 TeV proton-proton collisions with an integrated luminosity of 139 fb −1 collected by the ATLAS detector during LHC Run 2 operation. The sensitivity of the search is determined using models of the production and decay of spin-1 charged bosons and

Alphabetic Excavations : Johannes Bureus and the Runic Kabbalah

Around the turn of the 17th century, the Swedish antiquary and mystic Johannes Bureus (1568–1652) claimed to have discovered the primordial theology and science of his Scandinavian ancestors encoded in their system of writing, the runic alphabet, inspired in large part by earlier Christian interpretations of the Kabbalah. In the leadup to the Swedish intervention in the Thirty Years’ War, he viewe

Rethinking Gender in Orthodox Christianity

What is the role of gender in Eastern Christianity? In this volume, Orthodox experts of different disciplines and cultural backgrounds tackle this complex question. They engage critically with gender issues within their own tradition. Rather than simply accepting pervasive assumptions and practices, the authors challenge readers to reconsider historically or theologically justified views by offeriWhat is the role of gender in Eastern Christianity? In this volume, Orthodox experts of different disciplines and cultural backgrounds tackle this complex question. They engage critically with gender issues within their own tradition. Rather than simply accepting pervasive assumptions and practices, the authors challenge readers to reconsider historically or theologically justified views by offeri

The sins of the church: The long-term impacts of Christian missionary praxis on HIV and sexual behaviour in Zambia

This study examines the long-term effect of Christian missionary exposure on HIV infection and related sexual behaviour in Zambia. I use distance to a historical missionary church and health facility as proxies for missionary exposure. I constructed a geocoded data set combining information on the historical locations of churches and missionary health centres with contemporary individual-level dat

Search for dark photons from Higgs boson decays via ZH production with a photon plus missing transverse momentum signature from pp collisions at √s = 13 TeV with the ATLAS detector

This paper describes a search for dark photons (γd) in proton-proton collisions at s = 13 TeV at the Large Hadron Collider (LHC). The dark photons are searched for in the decay of Higgs bosons (H → γγd) produced through the ZH production mode. The transverse mass of the system, made of the photon and the missing transverse momentum from the non-interacting γd, presents a distinctive signature as i

Local colonisations and extinctions of European birds are poorly explained by changes in climate suitability

Climate change has been associated with both latitudinal and elevational shifts in species’ ranges. The extent, however, to which climate change has driven recent range shifts alongside other putative drivers remains uncertain. Here, we use the changing distributions of 378 European breeding bird species over 30 years to explore the putative drivers of recent range dynamics, considering the effect

Measurement of exclusive pion pair production in proton–proton collisions at √s=7TeV with the ATLAS detector

The exclusive production of pion pairs in the process pp→ ppπ+π- has been measured at s=7TeV with the ATLAS detector at the LHC, using 80μb-1 of low-luminosity data. The pion pairs were detected in the ATLAS central detector while outgoing protons were measured in the forward ATLAS ALFA detector system. This represents the first use of proton tagging to measure an exclusive hadronic final state at

Two warm Neptunes transiting HIP 9618 revealed by TESS and Cheops

HIP 9618 (HD 12572, TOI-1471, TIC 306263608) is a bright (G = 9.0 mag) solar analogue. TESS photometry revealed the star to have two candidate planets with radii of 3.9 ± 0.044 R (HIP 9618 b) and 3.343 ± 0.039 R (HIP 9618 c). While the 20.77291 d period of HIP 9618 b was measured unambiguously, HIP 9618 c showed only two transits separated by a 680-d gap in the time series, leaving many possibilit

J/ψ production at midrapidity in p-Pb collisions at √sNN = 8.16 TeV

The production of inclusive, prompt and non-prompt J/ψ was studied for the first time at midrapidity (−1.37 < y cms < 0.43) in p-Pb collisions at sNN = 8.16 TeV with the ALICE detector at the LHC. The inclusive J/ψ mesons were reconstructed in the dielectron decay channel in the transverse momentum (p T) interval 0 < p T < 14 GeV/c and the prompt and non-prompt contributions were separated on a st