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Commissioning of the test fel at MAX-Lab

An installation for testing techniques related to seeding and harmonic generation has been completed at MAXlab. The aim is to study the processes around seeded harmonic generation at 130/88/54 nm, the 2/3/5 harmonic of a Ti: Sapphire laser. During the spring 2008 the commissioning work has begun and this paper will report on the progress. The test FEL is built around the existing linac injector at

An 8-Bit, 100-MHz low glitch interpolation DAC

This paper describes an 8-Bit, 100-MHz current steering CMOS low glitch interpolation digital to analog converter (DAC). It includes a 16-tap voltage controlled delay line and 8-Bit based linear interpolators, making the effective clock rate up to 1.6-GHz. With the linear interpolation, the requirement on the analog reconstruction filter is relaxed, and low glitch digital to analog conversion is a

A CMOS gm-C IF filter for Bluetooth

An 18th (4th+14th) order gm -C IF filter for the Bluetooth short-range radio, implemented in a 0.6 μm CMOS process, is presented. The filter bandwidth is 1 MHz, the center frequency fc is 3 MHz, the in-band group delay variation is 0.75 μs, and the stop-band attenuation at fc±1 MHz is at least 47 dB. The noise floor is 250 μVr.m.s. and the spurious free dynamic range is at least 58 dB for out-of-b

Who Gets What in Coalition Governments? Predictors of Portfolio Allocation in Parliamentary Democracies

Ministerial portfolios are the most obvious payoffs for parties entering a governing coalition in parliamentary democracies. This renders the bargaining over portfolios an important phase of the government formation process. The question of ‘who gets what, and why?’ in terms of ministerial remits has not yet received much attention by coalition or party scholars. This article focuses on this quali

Collegiality and efficiency in bureaucracy

This article addresses the relation between the design of regulatory agencies and efficiency, arguing that authority concentrated to a single individual outperforms more collegial decision-making when the regulated firms’ interests are aligned. The tentative explanation is that concentrated leadership reduces the risk for capture. This argument is developed from an empirical case on the markets fo

Association between self-reported alcohol consumption and diastolic dysfunction : a cross-sectional study

BACKGROUND AND OBJECTIVES: While alcohol consumption is associated with common risk factors for diastolic dysfunction the independent impact of low levels of alcohol consumption on this condition in a community setting is still unclear.Thus, the aim of this study was to explore this association in a representative population sample employing optimal echocardiographic techniques.DESIGN: Cross-secti

Heart age gap estimated by explainable advanced electrocardiography is associated with cardiovascular risk factors and survival

Aims: Deep neural network artificial intelligence (DNN-AI)-based Heart Age estimations have been presented and used to show that the difference between an electrocardiogram (ECG)-estimated Heart Age and chronological age is associated with prognosis. An accurate ECG Heart Age, without DNNs, has been developed using explainable advanced ECG (A-ECG) methods. We aimed to evaluate the prognostic value

Contagious Transmission in a Swedish National Sample of Alcohol Use Disorders as a Function of Geographical Proximity Among Siblings and Propinquity-of-Rearing Defined Acquaintances

Objective: The purpose of this study was to determine whether alcohol use disorder (AUD) can be transmitted contagiously in siblings and likely acquaintances growing up close to one another (Propinquity-of-Rearing Defined Acquaintances [PRDAs]). Method: PRDAs were pairs of same-age subjects growing up within 1 km of each other and sharing the same school class, where one of whom (PRDA1) was first

Lump solutions of the fractional Kadomtsev–Petviashvili equation

Of concern is the fractional Kadomtsev–Petviashvili (fKP) equation and its lump solution. As in the classical Kadomtsev–Petviashvili equation, the fKP equation comes in two versions: fKP-I (strong surface tension case) and fKP-II (weak surface tension case). We prove the existence of nontrivial lump solutions for the fKP-I equation in the energy subcritical case α>45 by means of variational method

Effect of lateral wedged insoles on the knee internal contact forces in medial knee osteoarthritis

Background: Lateral wedge insoles (LWIs) are non-surgical interventions used in medial knee osteoarthritis (KOA) aiming at restoring correct joint biomechanics. However, the mechanical efficacy of LWIs, based on modulation of the external knee adduction moment, is partially proved and high variability in response to these devices was observed. Research question: The principal aim of the study was

Knee extensor muscle weakness and radiographic knee osteoarthritis progression : The influence of sex and malalignment

Background and purpose — Knee extensor (KE) muscle weakness is a modifiable feature commonly observed in individuals with knee osteoarthritis (KOA) and constitutes a potential target for patient-specific interventions. Therefore, in this study, we explored whether KE weakness is associated with radiographic (medial and/or lateral) KOA progression and how this relationship differs depending on fron

Frequent use of prescription NSAIDs among people with knee or hip osteoarthritis despite contraindications to or precautions with NSAIDs

Objective: To describe the use of non-steroidal anti-inflammatory drugs (NSAID), opioids, and physiotherapy (PT) among persons with newly diagnosed knee or hip osteoarthritis (OA) with and without NSAID contraindications or precautions. Design: We used population-based register data to identify adults aged ≥35 as of January 1, 2014, residing in Skåne region (Sweden) between 2004 and 2013, without

The deployment of new energy technologies and the need for local learning

The objective of this paper is to identify local aspects of technological learning in the deployment of solar photovoltaic (PV), a globally important form of distributed energy technology. We review literature in the economics of innovation and economic geography to identify the need for local learning when adopting new technologies and seek evidence on the local aspects of learning processes in t

Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver

Aim: To study the impact of aging on DNA methylation and mRNA expression in human liver. Experimental procedures: We analysed genome-wide DNA methylation and gene expression in human liver samples using Illumina 450K and HumanHT12 expression BeadChip arrays. Results: DNA methylation analysis of ∼455,000 CpG sites in human liver revealed that age was significantly associated with altered DNA methyl

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes

Type 2 diabetes has been reproducibly clustered into five subtypes with different disease progression and risk of complications; however, etiological differences are unknown. We used genome-wide association and genetic risk score (GRS) analysis to compare the underlying genetic drivers. Individuals from the Swedish ANDIS (All New Diabetics In Scania) study were compared to individuals without diab