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Diagnostic efficacy of MnDPDP in MR imaging of the liver. A phase III multicentre study

PURPOSE: To assess the diagnostic efficacy, safety and tolerability of mangafodipir trisodium (MnDPDP, Teslascan) in MR imaging of the liver. MATERIAL AND METHODS: Eighty-two patients from 4 centres underwent MR imaging with pre-contrast sequences including T1-weighted SE and GRE, and T2-weighted turbo SE sequences. MnDPDP at a dose of 5 mumol/kg b.w. was administered by slow i.v. infusion, and 20

History, clinical findings, sexual behavior and hygiene habits in women with and without recurrent episodes of urinary symptoms

BACKGROUND: To compare women with and without a history of recurrent symptoms suggestive of a urinary tract infection but a current negative urine culture regarding symptoms and signs of a genital infection, carriership of sexually transmitted agents and vaginal flora changes, sexual behavior and genital hygiene practice. SETTINGS: Contraceptive attendees at family planning and youth clinics. MATE

Isokinetic behaviour in gas phase catalytic hydrodechlorination of chlorobenzene over supported nickel

The kinetics of the hydrodechlorination (HDC) of chlorobenzene has been measured over Ni supported on a range of substrates (MgO, SiO2, Al2O3, Ta2O5, MgO, activated carbon (AC) and graphite) of varying BET area (9-843 m(2) g(-1)) where the Ni loading was in the range 1.5-20.3% (w/w) with catalyst preparation by impregnation and deposition-precipitation. The results of a comprehensive TEM analysis

Seediq – antisymmetry and final particles in a Formosan VOS language

This paper presents data from the Austronesian language Seediq, spoken in taiwan, which has both VOS order and final particles. It will be argued that the coccurrence of these two features is unexpected under a pre-antisymmetric analysis, whereas it is easily captured under an analysis couched in Kayne's Antisymmetry model, under the assumption that VOS order is derived by raising the predicate to

Stability of a single vortex in a trapped Bose-Einstein condensate

We investigate the lowest state of a Bose-Einstein condensate with an off-center vortex state that is confined in a rotating harmonic potential. Our results are consistent with the fact that any single off-center vortex is unstable. Furthermore, a vortex state located at the center of the cloud first becomes locally stable as the rotational frequency increases. Finally our study implies the existe

The 1.80-1.74-Ga gabbro-anorthosite-rapakivi Korosten Pluton in the Ukrainian Shield: a 3-D geophysical reconstruction of deep structure

The deep structure of the gabbro-anorthosite-rapakivi granite ("AMCG-type") Korosten Pluton (KP) in the northwestern Ukrainian Shield was studied by 3-D modelling of the gravity and magnetic fields together with previous seismic data. The KP occupies an area of ca. 12,500 km(2) and comprises several layered gabbro-anorthositic intrusions enveloped by large volumes of rapakivi-type granitoids. Betw

Apgar score predicts short-term outcome in infants born at 25 gestational weeks

Aim: To identify early predictors of outcome in infants born at 25 gestational weeks. Material and Methods: Data from a regional perinatal database (time-period 1995-2001, total n = 108 000 births) were used. Apgar scores were available in 92 preterm infants, born at 25 + 0 to 25 + 6 gestational weeks, and analyzed in relation to short-term outcome (180-day survival with, or without, severe brain

Influence of the block length of triblock copolymers on th formation of mesoporous silica

The effect of different block lengths of Pluronic surfactants, (EO)(x)-(PO)(y)-(EO)(x), in the formation of mesoporous silica has been investigated. The syntheses were performed in micellar solution of the surfactant under acidic conditions. The materials were characterized by SAXS, TEM and nitrogen adsorption measurements. The EO-block length of the polymers determines the mesostructure of the si

Complications after transpedicular stabilization of the spine. A survivorship analysis of 163 cases

OBJECTIVES. The authors studied complications of transpedicular stabilization methods. SUMMARY OF BACKGROUND DATA. One hundred and sixty-three consecutive transpedicular stabilization procedures were performed between January 1987 and December 1991. The indications for stabilization were trauma (33 cases), metastatic spinal disorder (30 cases), spinal stenosis (33 cases), spondylolisthesis (27 cas

Posttranscriptional regulation of TNFalpha expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages.

Resident mouse macrophages secrete Tumor necrosis factor α (TNFα) upon challenge with LPS. The production of TNFα is controlled not only at the transcription of the gene, but also by strong posttranscriptional regulation. When macrophages are stimulated with LPS different signal transduction pathways become activated. Here we show that the combination of the 2 kinases p38 and MEK and presumably ER

Effect of warmer climate on the depletion of snowcovered area in the Satluj basin in the western Himalayan region

The effect of warmer climate on the depletion of snow-covered area has been evaluated for the Satluj River basin located in the western Himalayan region in India. Snowmelt runoff contributes substantially to the annual streamflow of this river. In order to study the impact of three warming scenarios (T+1, T+2 and T+3degreesC), more than 160 new snow depletion curves were prepared for different ele

Overweight, obesity and fat distribution in 50-to 64-year-old participants in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Objective: To describe anthropometric characteristics of participants of the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: A cross-sectional analysis of baseline data of a European prospective cohort study. Subjects: This analysis includes study populations from 25 centres in nine European countries. The British populations comprised both a population-based and a 'he

Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase

Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides into deoxyribonucleotides, which constitute the precursor pools used for DNA synthesis and repair. Imbalances in these pools increase mutational rates and are detrimental to the cell. Balanced precursor pools are maintained primarily through the regulation of the RNR substrate specificity. Here, the molecular mechanism of t