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Playing with the child within : Early parenthood experiences of parents who were out-of-home placed during childhood

Experience of out-of-home care (OHC) is associated with life-long vulnerability, and research indicates that parents with experiences of OHC are at higher risk of having their own children placed in out-of-home care. However, research on these parents is limited and lacks a resilience perspective. Here, we focused on parents with OHC experience as children but with custody of their own children (N

Multiparticle integral and differential correlation functions

This paper formalizes the use of integral and differential cumulants for measurements of multiparticle event-by-event transverse momentum fluctuations, rapidity fluctuations, as well as net-charge fluctuations. This enables the introduction of multiparticle balance functions, defined based on differential correlation functions (factorial cumulants), that suppress two- and three-prong resonance dec

Microscale heterogeneity of phosphorus species associated with secondary mineral phases in the B horizons of two boreal Podzols

Poorly crystalline Al and Fe minerals have high sorption capacities for phosphate anions. However, there is still uncertainty about the molecular-level distribution of phosphorus (P) species between Al and Fe mineral phases, which can be relevant for bioavailability. The present study employed synchrotron X-ray microscopic techniques to distinguish between Al- and Fe-associated P phases in two Pod

Schreckstoff : It takes two to panic

Schreckstoff (fear substance) is an alarm signal released by injured fish that induces a fear response. Its chemical nature has long been debated. A new study finds that zebrafish Schreckstoff is composed of at least three components, two of which elicit the fear response only in combination.

A pilot scale study on the effects of various temperature and time conditions on milk quality using direct and indirect heating systems

Effects of various heating temperatures (124, 129, 134, 140 or 143 °C) and holding times (1 and 4 s) on milk quality using direct and indirect heating systems at pilot scale were investigated. Vitamin degradation was observed for both direct and indirect heating and the degradation increased with increasing temperature and holding time, however, no difference could be seen between heating systems.

Empirical evolution of an evacuation reporting template

Evacuation drills are frequently required components of health and safety processes, but they are often documented poorly (if at all), and thus might generate very little useful or actionable information. Given how much drills cost (in terms of potential risk to participants, financial overhead of downtime and restart time, etc.) it is perhaps surprising that even large organizations often lack a

Anti-KIF20B autoantibodies are associated with cranial neuropathy in systemic lupus erythematosus

Background Cranial neuropathies (CN) are a rare neuropsychiatric SLE (NPSLE) manifestation. Previous studies reported that antibodies to the kinesin family member 20B (KIF20B) (anti-KIF20B) protein were associated with idiopathic ataxia and CN. We assessed anti-KIF20B as a potential biomarker for NPSLE in an international SLE inception cohort. Methods Individuals fulfilling the revised 1997 Americ

Experimental investigation of the shear force capacity of prismatic cross laminated timber beams

Experimental tests of Cross Laminated Timber (CLT) under in-plane beam loading conditions are presented. The influence of the element layup, the individual lamination width, and the beam overhang at the supports on the shear force capacity was investigated. All the CLT beams had the same gross cross section, and a 4-point-bending test setup was used. The experimentally determined load-bearing capa

Esophagus Dilation and Quality of Life in Adults with Scleroderma and Concomitant Obstructive Sleep Apnea

(1) Background: Systemic sclerosis (SSc) is a rare systemic disease, which often affects the esophagus, leading to dilation and complications such as dysphagia and reflux. Obstructive sleep apnea (OSA) is a chronic condition with recurrent episodes of upper airway collapsibility and is known to impair quality of life (QoL). The primary aim of this study was to investigate the occurrence of esophag

Utilizing developmental dynamics for evolutionary prediction and control

Understanding, predicting, and controlling the phenotypic consequences of genetic and environmental change is essential to many areas of fundamental and applied biology. In evolutionary biology, the generative process of development is a major source of organismal evolvability that constrains or facilitates adaptive change by shaping the distribution of phenotypic variation that selection can act

Wildfire impacts on the carbon budget of a managed Nordic boreal forest

Wildfire is one of the most important disturbances affecting boreal forests. Most previous research on boreal forest fires has occurred in North American forests which have different fire regimes, tree species and are less intensively managed than their Eurasian counterparts. Recent extreme fire years have highlighted the vulnerability of the Nordic boreal forest to climatic shifts that are increa

Grotta Grande (southern Italy). Disentangling the Neandertal and carnivore interaction in a short-term palimpsest at the last glacial onset (∼116-109 ka)

The Mousterian of the Grotta Grande (Southern Italy) is here subject to new dating, which provide a surprisingly high-resolution on the stratigraphic sequence. Overall, the deposit in the Trench F appears framed in the MIS 5, into a brief chronological time span immediately after the Last Interglacial, between ∼116 ka and 109 ka. Significant archaeological evidence has been found in this sector on

Mortality risk relationship using standard categorized BMI or knee-height based BMI – does the overweight/lower mortality paradox hold true?

Background: The body mass index (BMI) is prone to misclassification of obesity due to age-related height loss and resulting measurement errors. Knee-height based BMI (KH-BMI) has not been previously studied in relation to mortality risk in older adults. Aim: To evaluate the age- and sex-specific mortality risk relationship using classic BMI and knee height predicted BMI (KH-BMI) overweight and obe

Structural complexity and benthic metabolism : resolving the links between carbon cycling and biodiversity in restored seagrass meadows

Due to large losses of seagrass meadows worldwide, restoration is proposed as a key strategy for increasing coastal resilience and recovery. The emergence of a seagrass meadow is expected to substantially amplify biodiversity and enhance benthic metabolism by increasing primary productivity and respiration. Nevertheless, open questions remain regarding the metabolic balance of aging seagrass meado

IL-2-mediated hepatotoxicity : knowledge gap identification based on the irAOP concept

Drug-induced hepatotoxicity constitutes a major reason for non-approval and post-marketing withdrawal of pharmaceuticals. In many cases, preclinical models lack predictive capacity for hepatic damage in humans. A vital concern is the integration of immune system effects in preclinical safety assessment. The immune-related Adverse Outcome Pathway (irAOP) approach, which is applied within the Immune

Factors influencing hospitalization or emergency department visits and mortality in type 2 diabetes following the onset of new cardiovascular diagnoses in a population-based study

Background: Individuals with type 2 diabetes (T2D) are at increased risk of developing cardiovascular disease (CVD) which necessitates monitoring of risk factors and appropriate pharmacotherapy. This study aimed to identify factors predicting emergency department visits, hospitalizations, and mortality among T2D patients after being newly diagnosed with CVD. Methods: In a retrospective observation

Bismuth oxymetallate-modified biochar derived from Euryale ferox husk for efficient removal of Congo red from wastewater : adsorption behavior and mechanisms

Using Euryale ferox husk as raw material, pristine biochar (EBC), Bi2MoO6-modified biochar (BM-EBC), and BiFeO3-modified biochar (BF-EBC) were prepared and employed for decontaminating Congo red (CR) from wastewater. Compared with EBC (217.59 mg/g) and BF-EBC (359.49 mg/g), a superior adsorption capacity of 460.77 mg/g was achieved by BM-EBC. Based on the evaluation results of the Freundlich and p

Inflammatory depression is associated with selective glomerular hypofiltration

Background: Systemic low-grade inflammation may be a pathophysiological mechanism in a subtype of depression. In this study we investigate a novel candidate mechanism of inflammatory depression - Selective Glomerular Hypofiltration Syndromes (SGHS) - which are characterized by a reduced estimated glomerular filtration rate (eGFR) based on cystatin C (cysC) relative to eGFR based on creatinine (cre

Interface-Engineered InAlN/Cu2O Photocathode with Accelerated Charge Separation for Boosting Photoelectrochemical Water Splitting

Cu2O has emerged as a promising material for sustainable hydrogen production through photoelectrochemical (PEC) water splitting, while inefficient charge separation remains one of the main challenges hindering its development. In this work, a new architecture of InAlN/Cu2O heterojunction photocathode is demonstrated by combining n-type InAlN and p-type Cu2O to improve the charge separation efficie

Polymer gel dosimetry for experimental verification of conformal small animal irradiation at a preclinical research platform

In translational research, there is a need for preclinical studies of high quality that corresponds to the conformal dose distributions conventionally delivered to humans in the modern radiotherapy clinic. To facilitate this need, novel preclinical systems consist of preclinical radiation platforms and small animal treatment planning systems. However, small-field dosimetry is challenging and requi