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Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors.

ABSTRACT: BACKGROUND: Urothelial carcinoma (UC) is characterized by nonrandom chromosomal aberrations, varying from one or a few changes in early-stage and low-grade tumors, to highly rearranged karyotypes in muscle-invasive lesions. Recent array-CGH analyses have shed further light on the genomic changes underlying the neoplastic development of UC, and have facilitated the molecular delineation a

När blev Jesus Guds Son?

Popular discussions over Jesus as the Son of God are mostly predetermined by the Creed or by a ”Christology from above”. Against this background the question on when Jesus began to be called ”Son of God” might be answered in a reductionist way, giving priority to the oldest and least developed forms of Christology. As a matter of fact, however, historical-critical exegesis has shown that titles an

Sahl and the Tājika Yogas: Indian transformations of Arabic astrology

This paper offers a positive identification of Sahl ibn Bishr’s Kitāb al-ʾaḥkām ʿalā ʾn-niṣba al-falakiyya as the Arabic source text for what is perhaps the most characteristic feature of the medieval Perso-Indian style of astrology known as tājika: the sixteen yogas or types of planetary configurations. The dependence of two late sixteenth-century tājika works in Sanskrit – Nīlakaṇṭha’s Tājikanīl

Behandling med intravenöst immunoglobulin vid neurologiska sjukdomar. Deskriptiv studie av effekter ur patientens och sjukvårdens perspektiv

We studied medical records for out-patient treatments with intravenous immunoglobulins during 2005 at the neurological clinics in Skåne and evaluated patient opinions using a questionnaire. Of 64 patients, 10 had started their therapy during the period, and 14 had it terminated. In five medical records doctor had defined and documented a therapy objective at the start of therapy and in six cases t

International network for comparison of HIV neutralization assays: the NeutNet report.

BACKGROUND: Neutralizing antibody assessments play a central role in human immunodeficiency virus type-1 (HIV-1) vaccine development but it is unclear which assay, or combination of assays, will provide reliable measures of correlates of protection. To address this, an international collaboration (NeutNet) involving 18 independent participants was organized to compare different assays. METHODS: Ea

From bilayers to micelles in a dilute surfactant system: a phase with a perforated bilayer network

The quaternary system comprising sodium dodecyl sulfate/water/pentanol/dodecane has been studied at high oil content and at two different water-to-surfactant ratios. Of particular interest is a highly flow birefringent, isotropic fluid phase, which occupies an island in the pseudo-ternary phase diagrams between the L2 phase and the L3 phase and which is in close proximity to the dilute lamellar ph

Tailoring harmonic radiation to different applications using a genetic algorithm

We use a genetic algorithm to theoretically optimize several properties of extreme ultraviolet (XUV) radiation, generated as high-order harmonics in xenon and argon. We maximize the harmonic pulse energy, minimize the pulse duration or optimize the temporal coherence by varying at the same time two or three parameters that are easily accessible in experiments, related to the characteristics of the

Mördarjakt i Ystad

The actual place for the murder cases is the small town Ystad in the south of Sweden. This is the scene for the films and books about the police inspector Kurt Wallander, created by the Swedish author and playwright Henning Mankell. Ystad is also the place where a new regional centre for film production is situated, and the Wallander movies play an important part in the economic conditions of this

Humanism och historiesyn i Kai Söderhjelms historiska barn- och ungdomsböcker

Kai Söderhjelm (b. 1918 in Helsinki, d. 1996 in Gothenburg) belonged to a Finland-Swedish cultural family, and was for many years an important and valuable figure in the intellectual life of Sweden. Söderhjelm’s authorship follows the same clear thematic lines from his first book, Rid mot nordväst (1948; Ride to the northwest), to his last, Okänt land (1993; Unknown land). These themes are peace,

Extreme Risks During the U. S. Financial Crisis: An Empirical Study of the Credit Default Swap Market

In this paper we focus on the many extreme credit default swap spread movements observed during the recent credit crisis. We find that the tails of the spread (and price) change distribution differ significantly from those of the normal distribution even for diversified credit derivatives portfolios. Particular focus is put on the sudden shift in the behavior of the credit default swap market in t