A well-functioning arterial system for the transport of oxygen to the cells is essential for human health. The aorta has a key role for the provision of this physiological effect. Disturbances to aortic function can lead to majorsymptoms and even death due to ruptured abdominal aortic aneurysm (AAA). Multiple diseases may exacerbate, or alleviate the symptoms of aortic conditions.This thesis exami

Vad är ett landskapsperspektiv? Jordbrukslandskap är multifunktionella – det vill säga att de bidrar direkt och indirekt med många olika värden. De är helt avgörande för produktionen av livsmedel och för lantbrukarens inkomster, men genererar också andra värden som inte alltid är lika synliga.

Syndecan-2 is a heparan sulfate proteoglycan that has a cell adhesion regulatory domain contained within its extracellular core protein. Cell adhesion to the syndecan-2 extracellular domain (S2ED) is β1 integrin dependent; however, syndecan-2 is not an integrin ligand. Here the protein tyrosine phosphatase receptor CD148 is shown to be a key intermediary in cell adhesion to S2ED, with downstream β

The ligand-binding domain of Fbl (the fibrinogen binding protein from Staphylococcus lugdunensis) shares 60% sequence identity with ClfA (clumping factor A) of Staphylococcus aureus. Recombinant Fbl corresponding to the minimum fibrinogen-binding region (subdomains N2N3) was compared with ClfA for binding to fibrinogen. Fbl and ClfA had very similar affinities for fibrinogen by surface plasmon res

Malaria is a potentially life-threatening disease with approximately half of the world’s population at risk. Young children and pregnant women are hit hardest by the disease. B cells and antibodies are part of an adaptive immune response protecting individuals continuously exposed to the parasite. An infection with Plasmodium falciparum can cause dysregulation of B cell homeostasis, while antibodi

Sediment transport in the cross-shore (CS) and associated changes in the beach profile, especially during storms, have been topics of widespread concern. Since storms are often accompanied by high water levels and large waves, large quantities of sand from the beach and the dune are typically transported offshore, leading to severe beach and dune erosion, which threatens the integrity of buildings

Analysis of a 13-year long, high-resolution data series on beach profiles, surveyed from 1981 to 1993 by the Army Field Research Facility (FRF) at Duck, North Carolina, in the United States, was analyzed in order to understand the temporal and spatial characteristics of the dune response. Various statistical methods were employed in this analysis. The profile survey data set was analyzed with rega

Venous thromboembolism (VTE) is the third most common cardiovascular disease. Low amount of mitochondrial DNA copy number (mtDNA-CN) has been associated with arterial cardiovascular disease (CVD) and reflects mitochondrial dysfunctions. However, whether mtDNA-CN is associated with VTE has not been determined. To examine the association between mtDNA-CN and incident VTE among middle-aged women. 691

Utställning, Prins Eugens Waldemarsudde, 24/4 – 3/10 2021.Det är hos den unga generationens kreatörer som idéer om framtidens mode först tar form. I utställningen Future Nordic Fashion visas ett urval visionära kreationer, som har skapats av några av de främsta nyexaminerade modedesigners inom ramen för den nordiska designtävlingen Designers´ Nest. Teman som lyfts fram i utställningen är dagsaktue

Purpose: The purpose of the paper is to theorize how to develop student entrepreneurs' ability to reflect by means of a learning activity called the entrepreneurial diary, which seeks to develop self-regulated learners capable of intelligent entrepreneurial action. The importance of self-regulation in entrepreneurship is linked to the individual's ability to make judgments under conditions of unce

Bin är en del av den biologiska mångfalden och bidrar dessutom med pollineringstjänster i våra odlade grödor och trädgårdsväxter. Men många arter är hotade och minskar i antal, med minskande biologisk mångfald som följd. Vilka konsekvenser får detta för jordbruksproduktionen? Genom att identifiera hoten och hitta motåtgärder finns det hopp om en väg framåt som gynnar alla.

Climate warming has caused the seasonal timing of many components of ecological food chains to advance. In the context of trophic interactions, the match–mismatch hypothesis postulates that differential shifts can lead to phenological asynchrony with negative impacts for consumers. However, at present there has been no consistent analysis of the links between temperature change, phenological async

Dual-energy X-ray absorptiometry (DXA)-derived appendicular lean mass/height2 (ALM/ht2) is the most commonly used estimate of muscle mass in the assessment of sarcopenia, but its predictive value for fracture is substantially attenuated by femoral neck (fn) bone mineral density (BMD). We investigated predictive value of 11 sarcopenia definitions for incident fracture, independent of fnBMD, fractur

Purpose: Lemierre syndrome is a life-threatening condition characterized by head/neck bacterial infection, local suppurative thrombophlebitis and septic embolic complications in a range of sites of distant organs. No prior study focused on the course and characteristics of ophthalmic complications of Lemierre syndrome. Methods: We analysed data of 27 patients with ophthalmic complications from a l