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On modelling the global copper mining rates, market supply, copper price and the end of copper reserves

The world supply and turnover of copper was modelled using simple empirical estimates and a COPPER systems dynamics model developed for this study. The model combines mining, trade markets, price mechanisms, population dynamics, use in society and waste as well as recycling, into a whole world system. The degree of sustainability and resource time horizon was estimated using four different methods

The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.

Breast cancer exhibits significant molecular, pathological, and clinical heterogeneity. Current clinicopathological evaluation is imperfect for predicting outcome, which results in overtreatment for many patients, and for others, leads to death from recurrent disease. Therefore, additional criteria are needed to better personalize care and maximize treatment effectiveness and survival.

New religious movements and science: Rael's progressive patronizing parasitism

The article examines the concoction of religion and science contained in the revelation that substantiates a new religion: Raelianism, founded and led by the prophet Claude Vorilhon/Rael after having received a revelation in 1974. After a detailed examination both of Rael's prophetic message and his/the Raelians' interpretative practices, an ad hoc model is presented to describe such concoction (p

Joint DOA and Multi-Pitch Estimation Using Block Sparsity

In this paper, we propose a novel method to estimate the fundamental frequencies and directions-of-arrival (DOA) of multi-pitch signals impinging on a sensor array. Formulating the estimation as a group sparse convex optimization problem, we use the alternating direction of multipliers method (ADMM) to estimate both temporal and spatial correlation of the array signal. By first jointly estimating

Språkvård för språkutveckling : Språk, språknormer och elevspråkbruk ur ett utbildningsperspektiv.

The Swedish classroom of today displays linguistic, cultural, and social diversity. Hence, if a teacher is to be able to assist each pupil in a language development regarding the elaborated language as well as the private, a new kind of work with language care and deeper knowledge of language norms are required. Furthermore, the elaborated language is consistently changing as a result of the logic

Possibilities for sustainable biorefineries based on agricultural residues - A case study of potential straw-based ethanol production in Sweden

This study presents a survey of the most important techno-economic factors for the implementation of biorefineries based on agricultural residues, in the form of straw, and biochemical conversion into ethanol and biogas, together with production of electricity and heat. The paper suggests locations where the necessary conditions can be met in Sweden. The requirements identified are regional availa

A New Pedagogical Approach for Integrating Social Work Students and Service Users

This paper analyses recent experiences at the School of Social Work, Lund University, the first in Sweden to use an innovative pedagogical approach for integrating social service users with social work students in the classroom (an EU-funded project). The concept of gift exchange was used to make sense of the approach. Gift exchange is based on the norm of reciprocity and the principles of gift ec

Signals of tree volume and temperature in a high-resolution record of pollen accumulation rates in northern Finland

Pollen accumulation rates (PARs) provide a potential proxy for quantitative tree volume (m3 ha-1) reconstruction with reliable absolute pollen productivity estimates (APPEs). We obtained APPEs for pine, spruce and birch at their range limits in northern Finland under two temperature periods (warm and cold) based on long-term pollen trap and tree volume records within a 14-km radius of each trap. A

Atmospheric constraints on gross primary productivity and net ecosystem productivity : results from a carbon-cycle data assimilation system

This paper combines an atmospheric transport model and a terrestrial ecosystem model to estimate gross primary productivity (GPP) and net ecosystem productivity (NEP) of the land biosphere. Using atmospheric CO2 observations in a Carbon Cycle Data Assimilation System (CCDAS) we estimate a terrestrial global GPP of 146 +/- 19 GtC/yr. However, the current observing network cannot distinguish this be

Evaluation of image reconstruction methods for 123I-MIBG-SPECT: a rank-order study.

Background: There is an opportunity to improve the image quality and lesion detectability in single photon emission computed tomography (SPECT) by choosing an appropriate reconstruction method and optimal parameters for the reconstruction. Purpose: To optimize the use of the Flash 3D reconstruction algorithm in terms of equivalent iteration (EI) number (number of subsets times the number of itera

Contact allergy to fragrances with a focus on oak moss absolute

The exposure to fragrances is widespread and contact allergy to fragrance substances affects 1–4% of the general population. Many fragrance substances are volatile and it can therefore be suspected that they may evaporate from petrolatum patch test preparations applied in test chambers. In the first two papers included in this thesis the aims were to i) to investigate the stability of fragrance pr

Levosimendan in early experimental sepsis: effects on the heart and hepatosplanchnic circulation

Popular Abstract in Swedish Blodförgiftningen (sepsis) kan ge upphov till akut hjärtsvikt, vilken på cellulär nivå karakteriseras av minskad känslighet för kalciumjonen och de vanliga hjärtförstärkande medicinerna (inotropa farmaka). Avhandlingen handlar om tidig behandling av sepsis-associerad hjärtsvikt med den kalciumsensitiseraren levosimendan, ett nytt läkemedel som höjer hjärtats kontraktionSepsis-related cardiovascular dysfunction associated with fluid-unresponsive tissue hypoperfusion might require inotropic treatment. This cardiovascular dysfunction seems to involve calcium desensitization and adrenergic unresponsiveness. We investigated the effects of clinically relevant plasma concentrations of the calcium sensitizer levosimendan during the first 6 h of endotoxemia in a model of

On Brain Oedema

Traumatic brain injury and bacterial meningitis may at a glance appear as two different disease entities. The host reaction, however, to both trauma and infection involves a strong inflammatory response, with the classical symptomology of rubor, tumor, calor, dolor et functio laesa. Tumor, swelling, will increase the volume within the closed cranial vault, and may thereby raise the intracranial pr

Chiral bicyclo[3.3.1]-3,7-dioxanonane derivatives: Study of crystallization mode and conformational dynamics in solution

A homologous series of chiral bis-ketals and mixed hemiketal-ketals with rigid bicyclo[3.3.1]-3,7-dioxanonane skeleton has been prepared. The crystallization mode (conglomerate or racemic compound) was established by chiral HPLC with double UV/polarimetric detection. The study of the solid-state structure by single crystal X-ray diffraction disclosed interesting CH ... pi intermolecular interactio

Cardiovascular mortality in bipolar disorder: a population-based cohort study in Sweden

Objective To estimate the cardiovascular mortality among persons with bipolar disorder in Sweden compared to the general population. Design Population register-based cohort study with a 20-year follow-up. Setting Sweden. Participants The entire population of Sweden (n=10.6 million) of whom 17101 persons were diagnosed with bipolar disorder between 1987 and 2006. Main outcome measures Mortality rat