Cartilage proteoglycans in synovial fluid and serum in patients with inflammatory joint disease. Relation to systemic treatment.
Proteoglycan concentrations in knee joint synovial fluid and in serum from patients with various inflammatory arthritides were studied using an enzyme-linked immunosorbent assay. Patients with reactive arthritis, calcium pyrophosphate arthorpathy, and juvenile rheumatoid arthritis (age ≤20 years) had the highest synovial fluid concentrations. These values differed significantly (P < 0.001) from th