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Evolving Concept of Small Vessel Disease through Advanced Brain Imaging.

Imaging plays a crucial role in studying and understanding cerebral small vessel disease. Several important findings have emerged from recent applications of advanced brain imaging methods. In patients with acute lacunar syndromes, diffusionweighted MRI studies have shown that the diagnostic precision of using clinical features alone or combined with CT scan findings to diagnose small vessel disea

Asymptotics for the size of the largest component scaled to "logn" in inhomogeneous random graphs

We study inhomogeneous random graphs in the subcritical case. Among other results, we derive an exact formula for the size of the largest connected component scaled by logn, with n being the size of the graph. This generalizes a result for the "rank-1 case". We also investigate branching processes associated with these graphs. In particular, we discover that the same well-known equation for the su

Benthic environmental responses to climatic changes during the late Quaternary: a micropalaeontological and geochemical approach

Popular Abstract in Swedish Genom att använda marina sedimentkärnor från havbotten kan vi dyka ner i forna tiders hav och förstå hur klimat och havsmiljö har utvecklats över tid. Sedimenten och dess innehåll av olika mikrofossil utgör ett fantastiskt miljöarkiv och ju längre ner i sedimenten vi kommer desto äldre är de vanligtvis. I mitt doktorandprojekt har jag studerat marina sediment från kusteThere is a limited understanding of how the benthic environment within upwelling regions responded to past rapid climatic changes. Within this thesis, a multiproxy approach is applied to two marine sediment cores from two coastal upwelling sites in the low latitude subtropical Atlantic. With a focus on benthic foraminiferal faunal analyses, the response of the benthic environment to rapid climatic

1/f-noise in Vertical InAs Nanowire Transistors

The material quality at high-k interfaces are a major concern for FET devices. We study the effect on two types of InAs nanowire (NW) transistors and compare their characteristics. It is found that by introducing an inner layer of Al2O3 at the high-kappa interface, the low frequency noise (LFN) performance regarding gate voltage noise spectral density, S-Vg, is improved by one order of magnitude p

Evaluation of a new immunoassay for cystatin C, based on a double monoclonal principle, in men with normal and impaired renal function

Elevated cystatin C in blood reflects impaired glomerular filtration rate (GFR), but current cystatin C assays, based on polyclonal antibodies and immunoturbidimetric or nephelometric detection, have several limitations. We evaluated a new immunoassay based on monoclonal antibodies in samples from patients with and without chronic kidney disease (CKD). The study enrolled 170 men without known CKD

IGF, PI3K and HIF-2 in Normal and Tumor Development

Popular Abstract in Swedish Neuroblastom är en allvarlig cancerform som nästan enbart drabbar barn. Denna typ av tumörer hittas i vävnader av det sympatiska nervsystemet (vilket är en del av det icke viljestyrda nervsystemet i kroppen). Allra vanligast är det att tumörerna bildas i binjuren, ett organ placerat strax ovanför njuren. Cancer är en komplex sjukdom och varje tumör är speciell på sitt sCells adapt to oxygen shortage, hypoxia, by inducing a transcriptional shift governed mainly by Hypoxia Inducible Factor (HIF)-1 and HIF-2. In various cancer forms, including neuroblastoma, high expression of HIF-2α correlates with disseminated disease and poor outcome. It has become evident that HIF-1 and HIF-2 are differentially regulated over time and by oxygen levels. HIF-2α is expressed in a

Electron and Hole Contributions to the Terahertz Photoconductivity of a Conjugated Polymer:Fullerene Blend Identified

Time-resolved terahertz spectroscopy was employed for the investigation of charge-transport dynamics in benzothiadiazolo-dithiophene polyfluorene ([2,7-(9,9-dioctylfluorene)-alt-S,S-(4',7'-di-2-thieny1-2',1',3'-benzothiadiazole)]) (APFO-3) polymers with various chain lengths and in its monomer form, all blended with an electron acceptor ([6,6]-phenyl-C61-butyric acid methyl ester, PCBM). Upon phot

Hydration and Mobility of Trehalose in Aqueous Solution.

The disaccharide trehalose stabilizes proteins against unfolding, but the underlying mechanism is not well understood. Because trehalose is preferentially excluded from the protein surface, it is of interest to examine how trehalose modifies the structure and dynamics of the solvent. From the spin relaxation rates of deuterated trehalose and (17)O-enriched water, we obtain the rotational dynamics

Modellering av klimatets påverkan på produktion och risk för skadegörare inom jordbruket.

I den här kunskapssammanställningen tar vi upp frågor som rör hur ett förändrat klimat kan komma att påverka tillväxt och skörd av olika jordbruksgrödor, samt hur klimatet kan påverka risken för angrepp av nya och redan etablerade skadegörare och växtsjukdomar i Sverige. Ökad temperatur leder till förlängning av växtsäsongen och utrymme för produktionsökning. I takt med att klimatet blir varmare k

AMFS: Adaptive Multi-Frequency Shading for Future Graphics Processors

We propose a powerful hardware architecture for pixel shading, which enables flexible control of shading rates and automatic shading reuse between triangles in tessellated primitives. The main goal is efficient pixel shading for moderately to finely tessellated geometry, which is not handled well by current GPUs. Our method effectively decouples the cost of pixel shading from the geometric complex

Diffusion in evaporating solutions

We present an analysis of the colloidal dynamics of particles in a mixture of two solvents subjected to evaporation. For simplicity, only one out of the two solvents is considered to be volatile. The evaporation generates a distribution of the solvent concentration in the system. As the particles selectively interact with the solvents, their migration becomes affected by a "chemotaxis" force, caus

In hot pursuit: fluctuating mating system and sexual selection in sand lizards

A changing climate is expected to have profound effects on many aspects of ectotherm biology. We report on a decade-long study of free-ranging sand lizards (Lacerta agilis), exposed to an increasing mean mating season temperature and with known operational sex ratios. We assessed year-to-year variation in sexual selection on body size and postcopulatory sperm competition and cryptic female choice.

Multi-component self-assembly of molecule based materials by coordination networks and weak intermolecular synthons

The coordination polymer [Fe(SCN)(2)(1,2-bis(4-pyridylmethylene)hydrazine)(2)](n) [Fe(phenanthroline)(3)](2n)(ClO4)(2n)center dot n1,2-bis(4-pyridylmethylene)hydrazine center dot 4nH(2)O 1 was crystallised from a MeOH/MeCN solution and the structure consists of layered (4,4) 2D-nets with supramolecular ([Fe(phen)(3)](2)bphz)(4+) units in the pores and disordered water and perchlorate anions. The s

Dimensions of some fractals defined via the semigroup generated by 2 and 3

We compute the Hausdorff and Minkowski dimension of subsets of the symbolic space Sigma(m) ={0, ... , m-1}(N) that are invariant under multiplication by integers. The results apply to the sets {x is an element of Sigma(m): for all k, x(k)x(2k) ... x(nk) = 0}, where n >= 3. We prove that for such sets, the Hausdorff and Minkowski dimensions typically differ.

Contributions in Sociology of Law. Remarks from a Swedish Horizon.

Lund University, Sweden, is the only seat of learning having Sociology of Law (hereafter SoL) at all levels in Europe. SoL was initiated in 1972 as a department at the Social Science Faculty, with professor Per Stjernquist as chair. Later on, for some 10 years, SoL was a division within the department of Sociology but from January 2006, SoL is an autonomous department at the Social Science Faculty

Time use among individuals with persistent mental illness: Identifying risk factors for imbalance in daily activities

The aim of this study was to investigate associations between time use in daily activities and sociodemographic and clinical factors in order to identify individuals with persistent mental illness at risk of having an imbalance in daily activities, as reflected in their time use and daily rhythm. Participants (n=103) were selected from a psychiatric outpatient unit using a randomized stratified se

First evidence of Devonian strata in Sweden - A palynological investigation of Ovedskloster drillcores 1 and 2, Skane, Sweden

Palynological analyses were carried out on 50 samples from the Ovedskloster 1 (O1) and 2 drillcores (O2), southern Sweden. The study revealed well-preserved palynological assemblages including 77 spore species in 28 genera, and some additional forms retained under open nomenclature. The spore assemblages are collectively dominated by trilete spores in terms of abundance and diversity and have been