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The neglect of treatment-construct validity in psychotherapy research: A systematic review of comparative RCTs of psychotherapy for Borderline Personality Disorder

Background: Randomized controlled trials (RCTs) are considered the best methodology for studying the efficacy of psychotherapy. Optimally an RCT design makes it possible to conclude that if one treatment has a better outcomethan another, this is due to the treatment package (TP) as it was implemented in this particular context, rather than other factors beyond the treatment (= high internal validi

Disc formation and the origin of clumpy galaxies at high redshift

Observations of high-redshift galaxies have revealed a multitude of large clumpy rapidly star-forming galaxies. Their formation scenario and their link to present-day spirals are still unknown. In this Letter, we perform adaptive mesh refinement simulations of disc formation in a cosmological context that are unrivalled in terms of mass and spatial resolution. We find that the so-called 'chain-gal

A pharmacoeconomic analysis of sertindole in the treatment of schizophrenia in Sweden

BACKGROUND: Atypical antipsychotics have similar clinical efficacy in the treatment of schizophrenia; variability in their tolerability represents the discerning factor in treatment choices. Sertindole has a relatively good tolerability profile that favours long-term patient adherence and, therefore, is associated with lower rates of relapse and rehospitalization.AIM: A model was developed to comp

ZrO2 and HfO2 dielectrics on (001) n-InAs with atomic-layer-deposited in situ surface treatment

The electrical properties of ZrO2 and HfO2 gate dielectrics on n-InAs were evaluated. Particularly, an in situ surface treatment method including cyclic nitrogen plasma and trimethylaluminum pulses was used to improve the quality of the high-κ oxides. The quality of the InAs-oxide interface was evaluated with a full equivalent circuit model developed for narrow band gap metal-oxide-semiconductor (

The effect of serum and certain serum electrolytes on the activity of testis hyaluronidase in carbonic acid-bicarbonate buffer pH 7.4

The effect of Ca++, Mg++, K+ and SO=4, and of serum, on the activity of testis hyaluronidase in a carbonic acid-bicarbonate buffer with pH 7.4 was investigated with the turbidimetric method. The ions were added in amounts corresponding to the serum concentration of the ion in question.The turbidity of hyaluronic acid was not modified by the investigated ions nor by serum up to 0.10 ml.The hyaluron

Human Rights and the Dark Side of Globalisation: Transnational Law Enforcement and Migration Control

This edited volume examines the continued viability of international human rights law in the context of growing transnational law enforcement. With states increasingly making use of global governance modes, core exercises of public authority such as migration control, surveillance, detention and policing, are increasingly conducted extraterritorially, outsourced to foreign governments or delegated

The role of knowledge variety and intensity for regional innovation

This paper analyses the effect of variety and intensity of knowledge on the innovation of regions. Employing data for Swedish functional regions, the paper tests the role of the variety (related and unrelated) and intensity of (1) internal knowledge generated within the region and also (2) external knowledge networks flowing into the region in explaining regional innovation, as measured by patent

Innovation strategies and firm performance : Simple or complex strategies?

This paper analyzes the effect of various innovation strategies (ISs) of firms on their future performance, captured by labor productivity. Using five waves of the Community Innovation Survey in Sweden, we have traced the innovative behavior of firms over a decade, that is, from 2002 to 2012. We defined ISs to be either simple or complex (in various degrees). We call an IS a simple IS when firms e

Motivation for change and personal resources in patients with prolonged musculoskeletal disorders

The purpose of this qualitative 2-year follow-up study was to obtain a deeper understanding of motivation for change towards an active and independent life in patients with prolonged musculoskeletal disorders and to explore and identify personal resources that might influence such improvements. Data collection and analysis were performed according to the qualitative case study design. An initial c