The plasma metabolome is associated with multiple phenotypes and diseases. However, a systematic study investigating clinical determinants that control the metabolome has not yet been conducted. In the present study, therefore, we aimed to identify the major determinants of the plasma metabolite profile. We used ultra-high performance liquid chromatography (UHPLC) coupled to quadrupole time of fli

This study examines the effects of teachable agents’ expressed self-efficacy on students. A total of 166 students, 10- to 11-years-old, used a teachable agent-based math game focusing on the base-ten number system. By means of data logging and questionnaires, the study compared the effects of high vs. low agent self-efficacy on the students’ in-game performance, their own math self-efficacy, and t

For diagnostic purpose, particles can be labeled with radionuclides or contain magnetizable materials making them suitable for external measurements of their biokinetics in vivo. In therapy, particles can be used as targetable drug-delivery systems or, if containing radioactivity, for internal radiation therapy. Loaded with, e.g., stable iodine, particles may also be used for photon activation the

Emulsions are found in a wide variety of food products, pharmaceuticals, paints, and cosmetics, thus emulsification is a truly multidisciplinary phenomenon. Therefore understanding of the process must evolve from the combination of (at least) three different scientific specializations. Engineering Aspects of Food Emulsification and Homogenization describes the state-of-the-art technology and bring

Polymer electrolyte membrane fuel cells (PEMFCs) fueled by hydrogen are considered to be most suitable for automotive applications owing to their fast dynamics and high power densities. However, the performances are limited primarily by processes in PEMFCs appeared in the catalyst layers (CLs), which highly dependon themicroscopic structure-related properties.TheCLs at both the anode and cathode h

Concerns regarding environmental issues have led to increasing efforts for investigating sustainable production routes for the future industry that is based on renewable resources. Among the biobased chemicals, the C3-chemicals 3-hydroxypropionaldehyde (3-HPA), 1,3-propanediol (1,3-PDO) and 3-hydroxypropionic acid (3-HP), have been identified as top candidates for the chemical industry. Lactobacil

Raptors are usually considered to be mainly visually dependent, and the use of other sensory modalities has rarely been studied in these birds. Here, we investigated experimentally which senses (vision and/or olfaction) Turkey vultures (Cathartes aura) and Southern caracaras (Caracara plancus) use to find hidden food. First, two identical stainless-steel perforated balls, one containing a putrefie

Correct electrode placement - a prerequisite for correct ECG interpretation Different lead misplacements may present with typical ECG changes, which may influence the management of the patient, if not identified and corrected. It is important, both for the ECG technician and for the interpreting physician, to recognize typical patterns of lead misplacement to avoid misinterpretation of the ECG.

Introduction: To reduce local recurrence rates when performing anterior resection in rectal cancer surgery Swedish national guidelines recommend rectal washout. This study aimed to describe current Swedish practice of rectal washout. Methods: Questionnaires were sent to Swedish surgical departments performing rectal cancer surgery. Results: Thirty-five units performed open rectal cancer surgery, a

A capacitive sensor for saccharide detection is described in this study. The detection is based on selective interaction between diols and aminophenylboronic acid (APBA) immobilized on a gold electrode. Glucose, fructose, and dextran (MW: 40 kDa) were tested with the system over wide concentration ranges (1.0 x 10−8 M - 1.0 x 10−3 M for glucose, 1.0 x 10−8 M - 1.0 x 10−2 M for fructose and 1.0 x 1

Lingonberries (LB) have been shown to have beneficial metabolic effects, which is associated with an altered gut microbiota. This study investigated whether the LB-induced improvements were associated with altered gut- and neuroinflammatory markers, as well as cognitive performance in ApoE−/− mice fed high-fat (HF) diets. Whole LB, as well as two separated fractions of LB were investigated. Eight-

We show that for several pattern graphs on four vertices (e.g., C4), their induced copies in host graphs with n vertices and no clique on k+1 vertices can be deterministically detected in O(n2.5719k0.3176+n2k2) time for k

Among the existing estimators of interactive effects (IEs) regressions, the common correlated effects (CCE) approach is probably the most popular. A major reason for this popularity is the generality of the approach. In fact, CCE is remarkably general in that it allows ample parameter heterogeneity without placing any restrictions on the true number of common factors. In the present paper, we show

Aim: Though caffeine is a consolidated treatment in preterm infants, the efficacy and safety of a higher dose have not been systematically appraised. Methods: A systematic review was conducted to compare high (loading dose >20 mg/kg and maintenance >10 mg/kg/day) versus low dose of caffeine. MEDLINE, EMBASE, Central and conference proceedings for randomised controlled trials (RCTs) and quasi-RCTs

Using transition metals in organic synthesis has led to the discovery of new reactions. These novel reactions have enabled different valuable transformations to take place through short synthetic routes and most importantly using a small amount of the metal. This small amount is called a catalytic amount and the metal which is in the form of a complex (with an array of groups of atoms bonded to thNew palladium and nickel complexes based on unsymmetric PCN pincer ligands have been synthesized and fully characterized using different techniques. The substituents on the nitrogen side arm of the ligand have great influence on the cyclometallation and the reactivity of the new complexes particularly in case of nickel. The less sterically hindered PCNMe ligand enabled formation of the trivalent n

AbstractTransition from fossil- to bio-based economy is a critical step towards reduction of greenhouse gas emissions and climate change, and hence for achievement of sustainable communities and environment. In order to be fossil-free, the chemical and material industry is in need of carbon-neutral building blocks from renewable resources for the diverse array of products that are currently produc

A focus on misrecognition allows us to move between levels of analysis in a holistic fashion. If misrecognition works through the conscious and the unconscious we can account for the many overlapping insecurities and securities believed to exist at the individual, group, or state level – and thus felt. These insecurities also present themselves through the categories used to describe them and the