Invasive lobular carcinoma (ILC) is the second most frequently occurring histological breast cancer subtype after invasive ductal carcinoma (IDC), accounting for around 10% of all breast cancers. The molecular processes that drive the development of ILC are still largely unknown. We have performed a comprehensive genomic, transcriptomic and proteomic analysis of a large ILC patient cohort and pres

Objective: To assess available evidence on the use of end-points ( outcome measures) in clinical trials in systemic lupus erythematosus (SLE), as a part of the development of evidence-based recommendations for points to consider in clinical trials in SLE. Methods: The European League Against Rheumatism (EULAR) Task Force on SLE comprised 19 specialists, a clinical epidemiologist and a research fel

BACKGROUND: Surveys are a common way to measure annoyance due to road traffic noise, but the method has some draw-backs. Survey context, question wording and answer alternatives could affect participation and answers and could have implications when comparing studies and/or performing pooled analyses. The aim of this study was to investigate the difference in annoyance reporting due to road traffi

Chromosome numbers are listed for 413 species of angiosperms from the Aegean Islands, based on collections and counts by Runemark and co-workers. Name, chromosome number and collection details (incl. geographical coordinates) are listed for each species. In almost all cases vouchers are at LD.

The aim of this multicenter study was to investigate whether a computer-assisted diagnosis (CAD) system could improve performance and reduce interobserver variation in bone-scan interpretations of the presence or absence of bone metastases. Methods: The whole-body bone scans (anterior and posterior views) of 59 patients with breast or prostate cancer who had undergone scintigraphy for suspected bo

Neutron-deficient nuclei with N = 126 have been populated following projectile fragmentation of a U-238 beam with energy 1 GeV/A. The decay of several previously reported isomers has been measured. This will allow us to calculate high-spin isomeric ratios and compare them with model calculations to allow a better understanding of the reaction mechanism.

Nanowires were grown by means of a novel aerosol-based method called Aerotaxy. Here an aerosol of Au catalyst nanoparticles in N-2 is mixed with MOVPE precursors in a flow-through reactor at atmospheric pressure, whereby nanowires are produced continuously in high concentrations. We demonstrate the possibility of in situ doping of the NWs and the realization of well-controlled p-type GaAs nanowire

Generalized frequency division multiplexing (GFDM) is a new digital multicarrier concept. The GFDM modulation technique is extremely attractive for applications in a fragmented spectrum, as it provides the flexibility to choose a pulse shape and thus allows reduction of the out-of-band leakage of opportunistic cognitive radio signals into incumbent frequency space. However, this degree of freedom

Laminar burning velocities of syngas/air premixed flames, varying with H-2/CO ratio (from 5/95 to 75/25) and N-2 or CO2 dilution rate (from 0% to 60%), were accurately measured using a Teflon coated Heat Flux burner and OH-PLIF based Bunsen flame method. Experiments were carried out at atmospheric pressure and room temperature, with fuel/air equivalence ratios ranging from fuel-lean to fuel-rich.

The intense competition between places means that new and more differentiated marketing strategies are becoming increasingly important in order to attract visitors and other target groups. In order to be seen, gain positive media attention and put the place on the map many cities try to develop marketing concepts based on experiences, among other things. One such strategy used by many places is to

Background: The aim was to describe the feeding-and stooling patterns of infants with colic and evaluate the influence of minimal acupuncture. Methods: A prospective, randomized, controlled, blind clinical study was conducted at a private acupuncture clinic in Sweden. 90 otherwise healthy 2-8 weeks old infants, born after gestational week 36, fulfilling the criteria for infantile colic and not med

The aim of this pilot study was to assess the association between perceived environmental barriers and perceived participation in everyday life situations encountered by people with late effects of polio. A sample of 45 persons with clinically verified late effects of polio answered the Swedish versions of the Impact on Participation and Autonomy Questionnaire (IPA-S) and the Craig Hospital Invent

BACKGROUND: The aim of this study was to explore changes in mobility in terms of ambulation and transfer over 1 year in patients with early-onset Alzheimer's disease (EOAD), and to compare mobility in EOAD with patients with other types of early-onset dementia (EOOD). METHOD: Forty-two patients with EOAD and 30 patients with EOOD were included. All patients were home-dwelling and had mild or moder

Popular Abstract in Swedish Gråstarrskirurgi är en av de vanligaste kirurgiska ingreppen i Sverige med runt 90 000 operationer utförda varje år. En åldrande befolkning med ökade krav på livskvalitet och god synskärpa har lett till en ökad operationsfrekvens och fler kirurger behöver utbildas. Utbildning av nya gråstarrskirurger sker förutom ett fåtal träningstillfällen på grisar, framförallt på paCataract surgery is one of the most common surgical procedures in Sweden and around 90 000 operations are made each year. An aging population with increased demands on quality of life and good visual acuity, has led to an increased rate of surgery and more surgeons needs to be trained. Training of new cataract surgeons is done on scarce wet-lab training but mainly on patients. Training is costly a

Fire accidents in underground transportation systems, e.g., tunnels and underground stations, can cause many fatalities. It is therefore important in fire safety design to give adequate consideration to all aspects related to evacuation. The paper provides a review of two previously reported fire accidents based on a theoretical framework, namely four accepted human behaviour theories. These theor