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Technological and policy solutions for transitioning to a fossil-free society exist, many countries could afford the transition, and rational arguments for rapid climate action abound. Yet effective action is still lacking. Dominant policy approaches have failed to generate action at anywhere near the rate, scale or depth needed to avoid potentially catastrophic futures. This is despite 30 years o

Groundwater (GW) resources provide a large share of the world's water demand for various sections such as agriculture, industry, and drinking water. Particularly in the arid and semi-arid regions, with surface water scarcity and high evaporation, GW is a valuable commodity. Yet, GW data are often incomplete or nonexistent. Therefore, it is a challenge to achieve a GW potential assessment. In this

The master regulator of neuroendocrine differentiation, achaete-scute complex homolog 1 (ASCL1) defines a subgroup of lung adenocarcinoma. However, the mechanistic role of ASCL1 in lung tumorigenesis and its relation to the immune microenvironment is principally unknown. Here, the immune landscape of ASCL1-positive lung adenocarcinomas was characterized by immunohistochemistry. Furthermore, ASCL1

Energy dispersive x-ray spectroscopy in a transmission electron microscope is often the first method employed to characterize the composition of nanowires. Ideally, it should be accurate and sensitive down to fractions of an atomic percent, and quantification results are often reported as such. However, one can often get substantial errors in accuracy even though the precision is high: for nanowir

Neuropsychiatric disturbances with altered social cognition, depression and anxiety are among the most debilitating early features in the fatal neurodegenerative disorder Huntington disease (HD) which is caused by an expanded CAG repeat in the huntingtin gene. The underlying neurobiological mechanisms are not known. Neuropathological analyses of postmortem human HD hypothalamic tissue have demonst

This study aims to enhance our understanding of organizational identity work (OIW), building upon previous studies’ emphasis on the usefulness of understanding OIW in terms of storytelling. The paper offers an extended vocabulary for making sense of alternative narration forms. Based on an in-depth study of a humanitarian organization in Sweden, the discursive OIW struggles of employees in times o

Purpose: To report a severe phenotype of retinitis pigmentosa associated with novel mutations in CNGB1. Observations: Six siblings, age range 50–75 years old, were examined using optical coherence tomography and fundus autofluorescene, electroretinogram testing, Goldman visual field testing, and genetic testing using next generation sequencing. In four affected siblings, two novel compound heteroz

Introduction: Preeclampsia (PE) is a human specific pregnancy-related syndrome of unknown etiology that affects 2–8 % of pregnancies. Polymorphism in maternal Killer Cell Immunoglobulin-like Receptors (KIRs) and the ligand fetal Human Leukocyte Antigen-C (HLA-C) may predispose pregnant mothers for PE due to defective trophoblast invasion into the maternal decidua. Our study aimed to investigate th

In research about degraded towns two cognitive currents can be observed: empirical (what? how? where? when?) and theoretical (why?). Contrarily, no study to date has dealt with the issue of discursivity of its central concept ‘degradation’, i.e. its a priori linguistic characterization determining ways in which research on the subject has been done. As geographers, we are fascinated by the ”real”

In this concluding chapter, our aim is to outline the state-of-the-art within the deliberated topic in order to identify challenges for future research. Firstly, reminiscent of George Orwell’s aphorism “who controls the past controls the future”, we stress the importance of research into the origins of degraded and restituted towns in order to understand the socio-economic context that has shaped

Degradations in Poland are sometimes made on an individual basis. Most often, however, they are the result of large-scale administrative reforms. Throughout history, the Polish lands were subject to many such reforms. Relatively little-known is the Polish reform of 1933–1934, which – depending on the definition of ‘city’ – degraded up to 722 units with some form of urban denominator. The modest no

One important element in the interaction between the natural and the human environment is the negative impact of the first on the latter when seen through the prism of urban destabilization. Within this scope, the issue of urban abandonment and disappearance holds an important place, the indirect cause of which are the specifics of local and regional natural subsystems. Small towns are especially

One of the less known problems in settlement geography is the issue of so-called degraded and restituted towns. This lack of reconnaissance, however, is perhaps less the result of the towns’ scarcity than their specificity of being ‘awarded’ or ‘deprived of’ an urban label by means of strictly socio-political actions. Degraded and restituted towns, hence, are spatial units made ‘urban’ or ‘rural’

Social deprivation and marginalization in urban areas are hardships that are not necessarily limited to developing countries. Around 80 million Europeans today live in conditions that fall within the definition of poverty. However, certain areas are more prone to affliction than others. Such estates usually consist of concrete slab high-rise buildings and are often characterized by high levels of

Concepts are the basic building blocks of all knowledge, while the strength of the theories that guide any societal project is dependent on the quality those concepts. Contrarily, the utilization of questionable concepts will result in questionable material effects. As two of the oldest geographical concepts still in widespread use, ‘rural’ and ‘urban’ stand in stark contrast to the immense change

We examined word associations in Swedish children with Developmental Language Disorder (DLD) compared to their typically developing (TD) peers. Furthermore, the study aimed to explore the dimensions of vocabulary knowledge (breadth, depth, and fluency) in these children. Fifty children (15 DLD and 35 TD) participated in the study, aged six to nine years. This age span is commonly associated with s

Meteoric beryllium-10 (10Be) is commonly used as a proxy of landscape dynamics (erosion and sedimentation rates) and soil development. Soil represents the first-stage reservoir of meteoric 10Be, and variability in the concentration of the isotope in soils may be affected by soil properties and atmospheric deposition. Although many investigations have targeted this issue, there are still problems i

The downscaling of silicon-based structures and proto-devices has now reached the single-atom scale, representing an important milestone for the development of a silicon-based quantum computer. One especially notable platform for atomic-scale device fabrication is the so-called Si:P δ-layer, consisting of an ultra-dense and sharp layer of dopants within a semiconductor host. Whilst several alterna

The intensification of agriculture has resulted in more homogeneous landscapes and declines of many species associated with farmland or other semi-natural open habitats. In parallel, forestry has also intensified causing declines in many species associated with old-growth forests. While intensive forestry negatively affects forest species, it inadvertently creates new habitats such as clear-cuts,