Optimizing cross-linking to study the interactions between AQP0 and CaM and AQP2 and LIP5
Mammals express thirteen different isoforms of the membrane-bound water channel aquaporin in a tissue-dependent manner. From a medical point of view, two of the most studied isoforms are aquaporin (AQP0), also known as major intrinsic protein and aquaporin 2 (AQP2). AQP0 is exclusively expressed in the mammalian eye lens and responsible for the transport of water across lens fiber cell membranes t