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Cigarette smoke exposure is strongly associated with airway hyperreactivity (AHR) which is the main characteristic seen in asthma. The intracellular MAPK signaling pathways are suggested to be associated with the airway damage to the AHR. In the present study, we hypothesize that secondhand cigarette smoke (SHS) exposure upregulates the bronchial contractile receptors via activation of the Raf/ERK

We studied the hyperfine structure and hyperfine coherent properties of the H-3(4)(0)-> D-1(2)(0) transition of Pr3+ ions in a tungstate single crystal La-2(WO4)(3) by hole-burning and photon-echo techniques. This work is motivated by the search of an efficient three level Lambda system in this new compound with which we could build up a quantum memory. By nonconventional hole-burning experiments,

The Icelandic highlands are one of the few places left in Europe where tourists can experience pristine wilderness. During the past decades the highlands have, however, witnessed a rapid expansion in natural resource exploitation. This study attempts to evaluate the pristine condition of Icelandic wilderness by testing different methods of identifying and analysing wilderness with respect to natur

Introduction: Patients with Alzheimer's disease (AD) are currently treated with cholinesterase inhibitors, such as galantamine, without actual knowledge of its concentration in plasma. Our objective was to analyse potential relationships between galantamine concentration, galantamine dose, socio-demographic characteristics, body weight, body mass index (BMI), and treatment response. Methods: Eight

Denna artikel reder ut den namnförbistring som funnits runt två pollenbaggar i vårt land. Det har visat sig att dessa två arter har haft olika namn nere på kontinenten och i Skandinavien. Och om man går efter de zoologiska namnreglerna så visar författarna i denna artikel att det är de namn som vi använt i Skandinavien som ska gälla. Detta har författarna konstaterat efter att ha tittat på de type

What can we learn from comparing different modes and moods of travel, among, for example, tourists and commuters? This paper contrasts these two very different kinds of mobility, and the ways in which they organise both motion and emotion. It is not only a question about how people interact with various systems of transport, but also how materialities and affects work together. An important topic

Plumage ornamentation often signals the quality of males and, therefore, female birds may choose elaborately ornamented mates to increase their fitness. Such mate choice may confer both direct and indirect benefits to the offspring. Males with elaborate ornaments may provide good genes, which can result in better nestling growth, survival or resistance against parasitic infections. However, these

This paper examines the importance of taste and health in food demand, as well as the effect on consumers’ experienced taste of the non-intrinsic value of healthy labels. Our analysis is based on taste experiments and Vickrey second price auctions on potato chips and bread. Our findings imply a large positive effect on demand, as measured by willingness to pay, for potato chips from higher taste s

Improvements in metabolite-profiling techniques are providing increased breadth of coverage of the human metabolome and may highlight biomarkers and pathways in common diseases such as diabetes. Using a metabolomics platform that analyzes intermediary organic acids, purines, pyrimidines, and other compounds, we performed a nested case-control study of 188 individuals who developed diabetes and 188

The aim was to confirm a previously defined prognostic index, combining a proliferation marker, histological grade, and estrogen receptor (ER) in different subsets of primary N0/N1 chemo-naïve breast cancer patients.

Film and history, interdisciplinarity. Introduction to a special feature issue

Background: Lentiviral vectors hold great promise as gene transfer vectors in gene therapeutic settings. However, problems related to the risk of insertional mutagenesis, transgene silencing and positional effects have stalled the use of such vectors in the clinic. Chromatin insulators are boundary elements that can prevent enhancer-promoter interactions, if placed between these elements, and prot

While the precise relationship between the Milky Way disk and the symmetry planes of the dark matter halo remains somewhat uncertain, a time-varying disk orientation with respect to an inertial reference frame seems probable. Hierarchical structure formation models predict that the dark matter halo is triaxial and tumbles with a characteristic rate of similar to 2 rad H-0(-1) (similar to 30 mu as

Measurements of the adiabatic laminar burning velocities of n-heptane, iso-octane, ethanol and their binary and tertiary mixtures are reported. Non-stretched flames were stabilized on a perforated plate burner at 1 atm. The Heat Flux method was used to determine burning velocities under conditions when the net heat loss from the flame to the burner is zero. Initial temperatures of the gas mixtures

The topic of this thesis is subjectless clauses in Old Swedish (1225–1526). The thesis focuses on referential subjects, and addresses the problem of why the possibilities to leave out such subjects have been reduced during the history of Swedish. The dissertation consists of three main parts, divided into eight chapters. In the first part, chapters 1–3, the aims are presented and a theoretical bac