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Cytotoxic alpha-pyrones from Xylaria hypoxylon

Two new alpha-pyrone derivatives, xylarone (1) and 8,9-dehydroxylarone (2) possessing cytotoxic activities, were isolated from the culture fluid of submerged cultures of the ascomycete Xylaria hypoxylon, strain A27-94. Their structures were elucidated by spectroscopic methods.

ThePEG, PYTHIA7, HERWIG ++ and ARIADNE

I present the status of the T(HE)PEG project for creating a common platform for implementing C++ event generators. I also describe briefly the status of the new versions of P-YTHIA, (HERWIG) and A(RIADNE) which are implemented using this framework. (c) 2005 Elsevier B.V. All rights reserved.

Essays on Risk in International Financial Markets

Popular Abstract in Swedish Denna avhandling behandlar metoder för att modellera risk på de finansiella marknaderna. Avhandlingen består av fyra separata uppsatser och inleds med en introduktion i kapitel ett, medan kapitel två till kapitel 5 består av de fyra uppsatserna. Den första uppsatsen undersöker implikationerna av att använda olika riskmått inom portföljval. Speciellt undersöks tre olikaThis thesis deals with techniques to model risk in financial markets and consists of four separate essays. The thesis begins with an introduction in chapter one, while chapter two to chapter five contains the four essays. The first essay examines the implication of using various risk measures for portfolio selection. Specifically, three risk measures are examined: variance, Value at Risk (VaR) an

Ultrasound assessment of endometrial morphology and vascularity to predict endometrial malignancy in women with postmenopausal bleeding and sonographic endometrial thickness >/= 4.5 mm.

Objectives To determine which endometrial morphology characteristics as assessed by gray-scale ultrasound and which endometrial vessel characteristics as assessed by power Doppler ultrasound are useful for discriminating between benign and malignant endometrium in women with postmenopausal bleeding (PMB) and sonographic endometrial thickness > 4.5 mm and to develop logistic regression models to ca

Impact on participation and autonomy questionnaire: internal scale validity of the Swedish version for use in people with spinal cord injury.

Objective: To evaluate aspects of internal scale validity and reliability of the Swedish version of the Impact on Participation and Autonomy questionnaire (IPA-S) for use in people with spinal cord injury. Subjects: A total of 161 persons with spinal cord injury. Method. IPA-S psychometric properties were evaluated using Rasch rating scale analysis. Results: The results show that the IPA-S has 27

Human achaete-scute homologue 1 (HASH-1) is downregulated in differentiating neuroblastoma cells

The mammalian achaete-scute homologue, MASH-1, is crucial for early development of the sympathetic nervous system and is transiently expressed in sympathetic neuroblasts during embryogenesis. Here we report that the human homologue (HASH-1) was expressed in all analyzed cell lines (6/6) derived from the sympathetic nervous system tumor neuroblastoma. The majority of small-cell lung carcinoma (4/5)

Hemithyroidectomy: Long-term effects on parathyroid function-preliminary report

Early hypocalcemia after thyroid surgery has frequently been reported, whereas data regarding long-term effects on calcium homeostasis are scarce. We have previously studied patients after hemithyroidectomy with an oral calcium load test and found normal parathyroid hormone (PTH) suppression. However, the 1,25-dihydroxyvitamin D concentration was decreased and the phosphate concentration increased

Smooth terminating bands in Te-112: Particle-hole induced collectivity

The Gammasphere spectrometer, in conjunction with the Microball charged-particle array, was used to investigate high-spin states in Te-112 via Ni-58(Ni-58, 4p gamma) reactions at 240 and 250 MeV. Several smooth terminating bands were established, and lifetime measurements were performed for the strongest one using the Doppler-shift attenuation method. Results obtained in the spin range 18-32h yiel

Onshore climate change during the late triassic marine inundation of the Central European Basin

Sedimentological, pedological and palynological evidence reveal radically increasing onshore humidity during the Rhaetian marine invasion of central Europe along the north-eastern margin of the Central European Basin (southern Sweden). Pre-Rhaetian aridity favoured the formation of Carnian redbeds with calcrete, which were succeeded by Norian hematite-cemented conglomerates, arkoses, arkosic wacke

Sverige har fackligt världsrekord

I artikeln framhålls att den internationellt mycket höga fackliga organisationsgraden i Sverige beror på flera faktorer: förekomsten av fackliga a-kassor och fackliga konfliktfonder, att den svenska fackföreningsrörelsen på en och samma gång är mer centraliserad och decentraliserad än i många andra länder samt frånvaron av splittring längs politiska eller religiösa skiljelinjer. Därtill kommer att

Myogenic vascular regulation in skeletal muscle in vivo is not dependent of endothelium-derived nitric oxide

The hypothesis, based on in vitro experiments on large conduit arteries, that endothelium-derived nitric oxide is a mediator of vascular myogenic reactivity was tested in cat gastrocnemius muscle in vivo. This was done by comparing, in the absence and presence of effective endothelium-derived nitric oxide blockade by the specific inhibitors NG-monomethyl-L-arginine or NG-nitro-L-arginine methyl es

Den kommunikativa utmaningen : En studie av kommunikationen mellan chef och medarbetare i en modern organisation

Popular Abstract in Swedish Chefer ägnar större delen av sin arbetstid – ca 80 procent - till att kommunicera med andra människor. Kommunikation har alltid haft en central roll i ledarskapet, men i dagens organisationer har kommunikationen blivit ännu viktigare och också svårare. Strävan efter delaktighet, delegering, arbete i nätverk och tvärfunktionella team innebär att kommunikationen mellan chThe focus of this dissertation is communication between managers and subordinates in a modern organization. The research questions are concerned with ideas, practices and organizational conditions in relation to leadership communication. My starting point for this study was the change in leadership philosophy that was introduced in many organizations at the beginning of the 1980s. This transforma

Glycaemic index methodology

The glycaemic index (GI) concept was originally introduced to classify different sources of carbohydrate (CHO)-rich foods, usually having an energy content of > 80 % from CHO, to their effect on post-meal glycaemia. It was assumed to apply to foods that primarily deliver available CHO, causing hyperglycaemia. Low-GI foods were classified as being digested and absorbed slowly and high-GI foods as b