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Rapidly developing viral resistance to licensed human immunodeficiency virus type 1 (HIV-1) protease inhibitors is an increasing problem in the treatment of HIV-infected individuals and AIDS patients. A rational design of more effective protease inhibitors and discovery of potential biological substrates for the HIV-1 protease require accurate models for protease cleavage specificity. In this stud

Since their emergence in the late 19th century, national park spaces have been perceived as articulations of untouched nature or wild landscape beyond society. Yet no understanding of national parks can do without the recognition that they exist in historical spaces created, institutionalised and prepared for them by cultural practices and modes of representation. Rather than being given by nature

Popular Abstract in Swedish Elmarknadens avreglering har medfört att behovet av "condition monitoring" eller tillståndskontroll har ökat. Den nya "marknaden" har medfört en annan typ av aktörer, som till skillnad mot de traditionella kraftbolagen, inte har samma kultur beträffande teknikorganisation. Därför har behovet av övervakningssystem ökat markant. Avhandlingen behandlar dessa ur ett teknisThe revenue from a power plant is strongly dependent on the life cycle cost. Today, when the market conditions for power-producing companies have shifted from a protected market to a deregulated market, the need for tools to monitor power plants has increased significantly. In this new competitive market, targeted revenues and operational economy drive the need for advanced monitoring tools. In th

This contribution presents a sample preparation methodology to enable the identification, with synchrotron radiation-based analytical techniques, of the gettering sites of metallic impurities on the internal walls of implantation-induced nanocavities in Si substrates. Preliminary results for the Cu-Si and Cu-Cu bond lengths on the internal surface of the nanocavities are reported. (C) 2002 Elsevie

Fatty acids are found in many solutions treated in ultrafiltration plants, for example, in dairy products, fermentation broth, oily waste water and bleach plant effluents from pulp mills. The influence of fatty acids on the fouling of membranes is often ignored because their concentration is rather low. However, during recent years the significant influence of fatty acids on the flux reduction of

Production of bioethanol from forest and agricultural products requires a fermenting organism that converts all types of sugars in the raw material to ethanol in high yield and with a high rate. This review summarizes recent research aiming at developing industrial strains of Saccharomyces cerevisiae with the ability to ferment all lignocellulose-derived sugars. The properties required from the in

Författarna har undersökt kvalster, hoppstjärtar och andra ryggradslösa djur på lavar som växer på stenmurar på Ölands alvar. Åtta olika kvalsterarter hittades. Generellt sett var vissa typer av lavar betydligt artrikare än andra. De rikaste är de som har strukturer som de små djuren kan gömma sig i.

Objective. Acute pancreatitis starts as an autodigestive process restricted to the pancreas and progresses to a systemic inflammation via cytokine release into the blood stream. Several inhibitors of the coagulation cascade, including active- siteinactivated factor VIIa, have shown anti- inflammatory properties in other inflammatory models than acute pancreatitis. Free radical scavengers have prov

We propose a technique integrating test scheduling, scan chain partitioning and test access mechanism (TAM) design minimizing the test time and the TAM routing cost while considering test conflicts and power constraints. Main features of our technique are (1) the flexibility in modelling the systems test behaviour and (2) the support for interconnection test of unwrapped cores and user-defined log

Different types of colonic dysganglionosis, and in particular intestinal neuronal dysplasia (IND) have been blamed for certain postoperative complications after surgery for Hirschsprung's disease (HD). We prospectively assessed colon innervation above the aganglionic zone (AZ) before proceeding to pull-through (PT) in order to rule-out IND as a cause of those complications. We first used a two-sta

The application of gold-coated glass capillaries for the design of a sensitive chemiluminescent immunoassay for 2,4-dichlorophenoxyacetic acid (2,4-D) is reported. The gold coating on the glass capillaries has been partially characterized and its effect on enhancing the signal intensity has been measured. A simple photo-multiplier tube-based photon detector is used for this purpose. At least three

We give a simpler proof of the formula, due to J.-L. Lions, for the reproducing kernel of the space of harmonic functions on a domain Omegasubset ofR(n) whose boundary values belong to the Sobolev space H-s(partial derivativeOmega), and also obtain generalizations of this formula when instead of harmonic functions one considers functions annihilated by a given elliptic partial differential operato