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The pro-inflammatory effect of uraemia overrules the anti-atherogenic potential of immunization with oxidized LDL in apoE-/- mice

Background. Uraemia increases oxidative stress, plasma titres of antibodies recognizing oxidized low-density lipoprotein (oxLDL) and development of atherosclerosis. Immunization with oxLDL prevents classical, non-uraemic atherosclerosis. We have investigated whether immunization with oxLDL might also prevent uraemia-induced atherosclerosis in apolipoprotein E knockout (apoE-/-) mice. Methods. ApoE

ICUD-EAU International Consultation on Bladder Cancer 2012: Non-Muscle-Invasive Urothelial Carcinoma of the Bladder

Context: Our aim was to present a summary of the Second International Consultation on Bladder Cancer recommendations on the diagnosis and treatment options for non-muscle-invasive urothelial cancer of the bladder (NMIBC) using an evidence-based approach. Objective: To critically review the recent data on the management of NMIBC to arrive at a general consensus. Evidence acquisition: A detailed Med

Measurement of angular correlations in Drell-Yan lepton pairs to probe Z/gamma* boson transverse momentum at root s=7 TeV with the ATLAS detector

A measurement of angular correlations in Drell-Yan lepton pairs via the phi(eta)* observable is presented. This variable probes the same physics as the Z/gamma* boson transverse momentum with a better experimental resolution. The Z/gamma* -> e(+)e(-) and Z/gamma* -> mu(+)mu(-) decays produced in proton-proton collisions at a centre-of-mass energy of root s = 7 TeV are used. The data were collected

The Ab Initio No-core Shell Model

This contribution reviews a number of applications of the ab initio no-core shell model (NCSM) within nuclear physics and beyond. We will highlight a nuclear-structure study of the A = 12 isobar using a chiral NN + 3NF interaction. In the spirit of this workshop we will also mention the new development of the NCSM formalism to describe open channels and to approach the problem of nuclear reactions

Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3 '-sulfo-lactose, and 2 '-fucosyllactose

Galectin-4 is a tandem-repeat galectin with two distinct carbohydrate recognition domains (CRD). Galectin-4 is expressed mainly in the alimentary tract and is proposed to function as a lipid raft and adherens junction stabilizer by its glycan cross-linking capacity. Galectin-4 plays divergent roles in cancer and inflammatory conditions, either promoting or inhibiting each disease progression, depe

Honeybee navigation: critically examining the role of the polarization compass

Although it is widely accepted that honeybees use the polarized-light pattern of the sky as a compass for navigation, there is little direct evidence that this information is actually sensed during flight. Here, we ask whether flying bees can obtain compass cues derived purely from polarized light, and communicate this information to their nest-mates through the 'waggle dance'. Bees, from an obser

Smooth 2-D frequency estimation using covariance fitting

In this paper, we introduce a non-parametric 2-D spectral estimator for smooth spectra, allowing for irregularly sampled measurements. The estimate is formed by assuming that the spectrum is smooth and will vary slowly over the frequency grids, such that the spectral density inside any given rectangle in the spectral grid may be approximated well as a plane. Using this framework, the 2-D spectrum

The Songbird Neurogenomics (SoNG) Initiative: Community-based tools and strategies for study of brain gene function and evolution

Background: Songbirds hold great promise for biomedical, environmental and evolutionary research. A complete draft sequence of the zebra finch genome is imminent, yet a need remains for application of genomic resources within a research community traditionally focused on ethology and neurobiological methods. In response, we developed a core set of genomic tools and a novel collaborative strategy t

No title

This article focuses on the roles played by the female characters in three of the most influential indigenista novels, Raza de bronce (1918) by the Bolivian author Alcides Arguedas, Huasipungo (1934) by Jorge Icaza, from Ecuador, and El mundo es ancho y ajeno (1941) by the Peruvian writer Ciro Alegría. The roles of the female characters are studied from the perspective of Mikhail Bakhtin’s notion

Swirl sign in intracerebral haemorrhage: definition, prevalence, reliability and prognostic value

Background: Swirl sign has previously been described in epidural hematomas as areas of low attenuation, radiolucency or irregular density. The aims of this study were to describe swirl sign in ICH, study its prevalence, study the reliability of the subjective evaluation on computed tomography (CT), and to explore its prognostic value. Methods: CTs of 203 patients with ICH were retrospectively eval

A. EUF-fördraget

Rättsfallskommentar avseende 2012 års domar från EU-domstolens som rör medlemsstaternas inkomstskatteregler

Synchrotron-based structural and spectroscopic studies of ball milled RuSeMo and RuSnMo particles as oxygen reduction electrocatalyst for PEM fuel cells

Particles of RuSeMo and RuSnMo have been produced by ball milling; they present catalytic activity towards the oxygen reduction reaction (ORR) in acid media. A Tafel slope close to 120 mV/dec was found for both materials. Their morphology was first characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). SEM and TEM images reveal particles in the sub-micromet

Fibroblasts as matrix modulating cells in asthma and COPD

Chronic lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are two lung diseases that are continuously increasing worldwide. Despite extensively research to find curative treatment, no so such therapy exists today. New hypothesis suggests that an aberrant chronic wound healing process takes place which involves both the classical inflammation and more chronic changes of