Search results

Filter

Filetype

Your search for "*" yielded 528916 hits

Bicycle sharing : Sustainable value creation and institutionalisation strategies in Barcelona

A highly debatable issue is whether or not a paradigm shift toward the sharing economy could help to address the economic, social and environmental challenges of our time. This article contributes to the academic discussion by exploring the types of value created by sharing organisations and the strategies they use to institutionalise themselves in relation to powerful institutions. The study appl

Effect of A-/B-site doping on oxygen non-stoichiometry, structure characteristics, and O2 releasing behavior of La1−xCaxCo1−yFeyO3−δ perovskites

Oxy-fuel combustion is one of the proposed technologies with the potential to achieve zero CO2 emission. La1−xCaxCo1−yFeyO3−δ (LCCF) perovskites are promising materials with high selectively for oxygen. In this study, the oxygen non-stoichiometry of perovskites LCCF was investigated by means of iodometric titration. LCCF was prepared using the liquid citrate method, and the phase structures were i

Ecological interventions in agricultural landscapes - scale matters!

The Common Agricultural Policy (CAP) affects about half of the land area of the EU and allocates close to 40% of the EU’s budget. Consequently, CAP has great potential to guide land management decisions towards multifunctional agricultural landscapes supporting both commodity production and biodiversity. The 2015 “greening” reform was an attempt to increase the multifunctionality of agricultural l

Bone mineral density and osteoporosis in heart transplanted patients : A single-center retrospective study at Skåne University Hospital in Lund 1988-2016

Bone mineral density (BMD) in the lumbar spine and femoral neck, the incidence of osteoporosis, and survival up to 10 years after heart transplantation (HT) were investigated in 169 patients who underwent HT at Skåne University Hospital in Lund, Sweden, 1988-2016. Within the first year post-transplantation, mean (SD) BMD decreased by 3.9% (10.1) (P < 0.001) and 9.0% (10.5) (P < 0.001) in the lumba

The effect of stricter capital regulation on banks’ risk-taking : Theory and evidence

A simple portfolio choice model shows that, when a bank's capital is constrained by regulation, regulatory cost (risk weightings) alters the risk and value calculations for the bank's assets. In particular, we find that banks may respond to stricter regulation by increasing the share of high-risk assets. Our empirical results show that US banks responded to the implementation of the stricter Basel

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

Objective: The capacity to precisely predict progression to type 1 diabetes (T1D) in young children over a short time span is an unmet need. We sought to develop a risk algorithm to predict progression in children with high-risk human leukocyte antigen (HLA) genes followed in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Methods: Logistic regression and 4-fold cross-valida

Fluorescence Anisotropy Reloaded—Emerging Polarization Microscopy Methods for Assessing Chromophores' Organization and Excitation Energy Transfer in Single Molecules, Particles, Films, and Beyond

Fluorescence polarization is widely used to assess the orientation/rotation of molecules, and the excitation energy transfer between closely located chromophores. Emerging since the 1990s, single molecule fluorescence spectroscopy and imaging stimulate the application of light polarization for studying molecular organization and energy transfer beyond ensemble averaging. Here, traditional fluoresc

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we performed genome-wide analyses of circulating HDL cholesterol, LDL cholesterol, and triglyceride levels in up to 120,979 individuals of European, African, Asian, Hispanic, and Braz

A simplified flow cytometric method for detection of inherited platelet disorders—A comparison to the gold standard light transmission aggregometry

Background Flow cytometric platelet activation has emerged as an alternative diagnostic test for inherited platelet disorders. It is, however, labor intensive and few studies have directly compared the performance of flow cytometric platelet activation (PACT) to light transmission aggregometry (LTA). The aims of this study were 1/ to develop a simplified flow cytometric platelet activation assay u

Nature vs nurture in knee osteoarthritis – the importance of age, sex and body mass index

Objective: (1) To estimate the life-time genetic contribution for knee osteoarthritis (OA) surgery and (2) to explore any differences in the genetic contribution across age, sex and body mass index (BMI). Methods: We studied the sex-specific genetic contribution to knee OA surgery in a prospective cohort study of 62,490 twins aged 35 years or older with a follow-up period of up to 47 years (10,092

Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors, and actin dynamics

The endothelin type B receptor (ETB or EDNRB) is highly plastic and is upregulated in smooth muscle cells (SMCs) by arterial injury and following organ culture in vitro. We hypothesized that this transcriptional plasticity may arise, in part, because EDNRB is controlled by a balance of transcriptional inputs from myocardin-related transcription factors (MRTFs) and ternary complex factors (TCFs). W

Yet another kinetic mechanism for hydrogen combustion

Recent suggestion by Burke and Klippenstein (2017) that chemically termolecular reactions H + O2 + R may significantly affect kinetic pathways under common combustion situations requires careful analysis, since, if included in contemporary kinetic mechanisms, these reactions affect global reactivity and calculated burning velocities of laminar premixed flames. In the view of their impact, a detail

Water Services Sustainability: Institutional Arrangements and Shared Responsibilities

Poor water services in developing countries after national conflict as a result of institutional setups and devastating infrastructures. This study assesses how institutional arrangements have affected the poor water services in Somalia, through thematic analyses. The huge gap in the literature about Somalia highlights the significant need of such research works and the originality of this paper.

Enabling room-temperature processed highly efficient and stable 2D Ruddlesden-Popper perovskite solar cells with eliminated hysteresis by synergistic exploitation of additives and solvents

Herein we demonstrate the favorable synergistic effect of an NH4Cl additive and DMSO solvent on 2D perovskites that are synthesized at room temperature. Interestingly, we observe the spontaneous formation of 3D phases within either NH4Cl or DMSO treated 2D perovskites, which plays a pivotal role in facilitating charge transport. It is revealed that NH4Cl increases charge carrier lifetime and passi

Arsenic alters global histone modifications in lymphocytes in vitro and in vivo

Arsenic, an established carcinogen and toxicant, occurs in drinking water and food and affects millions of people worldwide. Arsenic appears to interfere with gene expression through epigenetic processes, such as DNA methylation and post-translational histone modifications. We investigated the effects of arsenic on histone residues in vivo as well as in vitro. Analysis of H3K9Ac and H3K9me3 in CD4

Optimal plasmonic multipole resonances of a sphere in lossy media

Fundamental upper bounds are given for the plasmonic multipole absorption and scattering of a rotationally invariant dielectric sphere embedded in a lossy surrounding medium. A specialized Mie theory is developed for this purpose and when combined with the corresponding generalized optical theorem, an optimization problem is obtained which is explicitly solved by straightforward analysis. In partiFundamental upper bounds are given for the plasmonic multipole absorption and scattering of a rotationally invariant dielectric sphere embedded in a lossy surrounding medium. A specialized Mie theory is developed for this purpose and when combined with the corresponding generalized optical theorem, an optimization problem is obtained which is explicitly solved by straightforward analysis. In parti