Seventy-two alcoholic patients (60 men and 12 women) were randomized into four groups who received psychiatric treatment (PT) or multimodal behavioural therapy (MBT), for either 1 or 2 years. PT was based on psychodynamic principles, and MBT is a cognitive-behavioural treatment. The patients accepting treatment had a mean age of 37 ± 9 years, and they were socially stable. There was no difference

This paper contemplates the future of utility infrastructure, and considers whether an "All-in-One" approach could supply all necessary utility services to tomorrow's households.The intention is not to propose infrastructure solutions that are currently technically feasible or justifiable, however; the objective is to present visions of future infrastructure that would only be possible with new ad

Background Postural orthostatic tachycardia syndrome (POTS) is a variant of cardiovascular autonomic disorder occurring predominantly in young women. POTS is characterized by an excessive heart rate increase when assuming upright posture accompanied by symptoms of orthostatic intolerance. The pathophysiology of POTS has not been fully established and is believed to be multifactorial. Purpose We a

This book is a classic work of twentieth-century legal philosophy. The first translation into English was notably poor and misrepresented the views expressed in the text. Translated from scratch from the original Danish, this new critical edition casts light on the work and resituates it firmly in the context of current debates in the field.

The selection of control group is crucial, as the use of an inadequate group may strongly affect the results. In this study we examine the effect on contralateral tissue protein levels, in a model of unilateral UVB irradiation, as the contralateral side is commonly used as a control. Previous studies have shown that UVB irradiation increases immunoreactivity for inflammatory regulated neuropeptide

The Avobenzone (AVOB) molecule is very photoactive and undergoes irreversible degradation upon irradiation. We studied its valence and core-level (C1s and O1s) photoionisation and subsequent photofragmentation with photoelectron spectroscopy and photoelectron-photoion-photoion coincidence (PEPIPICO) spectroscopy. AVOB is one of the largest molecules studied with this technique. The results show th

We used the fact that patients with non-muscle invasive bladder tumors show local recurrences and multiple tumors to study re-initiation of tumor growth from the same urothelium. By extensive genomic analyses we show that tumors from the same patient are clonal. We show that gross genomic chromosomal aberrations may be detected in one tumor, only to be undetected in a recurrent tumor. By analyses

Between 25 and 50 per cent of white dwarfs (WD) present atmospheric pollution by metals, mainly by rocky material, which has been detected as gas/dust discs, or in the form of photometric transits in some WDs. Planets might be responsible for scattering minor bodies that can reach stargazing orbits, where the tidal forces of the WD can disrupt them and enhance the chances of debris to fall on to t

Background: The rising prevalence of type 2 diabetes (T2D) poses a major global challenge. It remains unresolved to what extent transcriptomic signatures of metabolic dysregulation and T2D can be observed in easily accessible tissues such as blood. Additionally, large-scale human studies are required to further our understanding of the putative inflammatory component of insulin resistance and T2D.

In this article, we consider scenarios in which traditional estimates for the active subspace method based on probabilistic Poincaré inequalities are not valid due to unbounded Poincaré constants. Consequently, we propose a framework that allows to derive generalized estimates in the sense that it enables to control the trade-off between the size of the Poincaré constant and a weaker order of the

På kort tid har coronapandemin utlöst en djup ekonomisk kris i Sverige. Härpresenterar vi en första obduktion av krisen. Vi jämför dagens krisförlopp medde två senaste kriserna, finanskrisen 1991–93 och den internationella finanskrisen 2008–09. Vi kartlägger hur svensk ekonomi har påverkats samt belyser de kortsiktiga samhällsekonomiska kriskostnaderna. Därefter beskrivs krispolitiken. Här ställs

Gothenburg is a flourishing green city, with nearly 600,000 inhabitants, located on the west coast of Sweden. Gothenburg has a long tradition of a strong civil society and grass roots movement, which is also reflected when it comes to the development of the sharing economy in the city. Many of the sharing initiatives come from civil society organizations, but the local government has also taken an