ABO exon and intron analysis in individuals with the A(weak)B phenotype reveals a novel O-1v-A(2) hybrid allele that causes four missense mutations in the A transferase
Background: Since the cloning in 1990 of cDNA corresponding to mRNA transcribed at the blood-group ABO locus, polymorphisms due to ethnic and/or phenotypic variations have been reported. Some subgroups have been explained at the molecular level, but unresolved samples are frequently encountered in the reference laboratory. Results: ABO blood grouping discrepancies were investigated serologically a
