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We investigate the generation of high-order harmonics using laser pulse energies in the few-mu J range at high repetition rates. We analyse how the conversion efficiency is influenced by the tight focusing geometry required for the generation of high-order harmonics under these conditions. A generalized phase-matching model allows us to discuss macroscopic phase effects independent of focal length
Epidemiological studies have examined breast cancer risk in relation to sex hormone concentrations measured by different methods: "extraction" immunoassays (with prior purification by organic solvent extraction, with or without column chromatography), "direct" immunoassays (no prior extraction or column chromatography), and more recently with mass spectrometry-based assays. We describe the associa
We aimed at investigating the distribution and risk of second primary cancers (SPCs) in multiple myeloma (MM) survivors in Germany and Sweden to provide etiological understanding of SPCs and insight into their incidence rates and recording practices. MM patients diagnosed in 1997-2010 at age ≥15 years were selected from the Swedish (nationwide) and 12 German cancer registries. Standardized inciden
BACKGROUND: Arsenic in drinking water causes severe health effects. Indigenous people in the South American Andes have likely lived with arsenic-contaminated drinking water for thousands of years. Inhabitants of San Antonio de los Cobres (SAC) in the Argentinean highlands generally carry an AS3MT (the major arsenic-metabolizing gene) haplotype associated with reduced health risks due to rapid arse
Light neutron-rich even-even nuclei, of which the ground state is oblately deformed, are looked for, examining the Nilsson diagram based on realisticWoods-Saxon potentials. One-particle energies of the Nilsson diagram are calculated by solving the coupled differential equations obtained from the Schrodinger equation in coordinate space with the proper asymptotic behavior for r -> infinity for both
Cigarette smoke is a strong risk factor for cardiovascular disease. However, the underlying molecular mechanisms that lead to cigarette smoke-associated cardiovascular disease remain elusive. With functional and molecular methods, we demonstrate for the first time that lipid soluble cigarette smoke particles (DSP) increased the expression of endothelin type B (ET(B)) receptors in arterial smooth m
This paper describes the characterisation of an ultra-thin silicon semicondoctor Delta E detector to be used as a pre-cell ion hit detector in single ion experiments on individual, living cells. The characteristics of interest for this specific application are the hit detection efficiency, which has to be close to 100% to enable bombardment with either a single ion or a counted number of ions, the
Förra året beslutade SLF att 'adoptera' Skäckerfjällen i Jämtland, vilket innebär att föreningen avser att göra en fullständig inventering av dess lavar genom återkommande besök under ett antal år. Första besöket gjordes under höstexkursionen 2008 i mångahanda spännande miljöer, såsom kalkbranter, bäckraviner med gammal granskog, videsnår, snölegor och fjälltoppar med urberg. Exkursionen resultera
We consider the problem of localizing a novel image in a large 3D model. In principle, this is just an instance of camera pose estimation, but the scale introduces some challenging problems. For one, it makes the correspondence problem very difficult and it is likely that there will be a significant rate of outliers to handle. In this paper we use recent theoretical as well as technical advances t
Markers of mercury (Hg) exposure have shown both positive and negative associations with cardiovascular disease (CVD). We assessed the association between serum Hg (S-Hg) and risk of cardiovascular disease in a prospective population-based cohort, with attention to the roles of dental health and fish consumption. Total mortality, as well as morbidity and mortality from acute myocardial infarction
Introduction. We aim to create an in-depth understanding of how pupils in upper secondary school negotiate the credibility and authority of information as part of their practices of learning. Particular focus is on the use of user-created resources, such as Wikipedia, where authorship is collective and/or hard to determine. Method. An ethnographic study was conducted in an upper secondary school c
Glioblastoma Multiforme (GBM) is the most abundant and most aggressive primary brain tumor in adults. Due to the infiltrative growth of the tumor, surgery will never be radical. Radiation and chemotherapy only marginally improve the poor prognosis due to the ability of the GBM to develop resistance towards these treatments. Therefore it is of great importance to find new efficient treatment modali
The use of acoustic forces to manipulate particles or cells at the microfluidic scale (i.e. acoustophoresis), enables non-contact, label-free separation based on intrinsic cell properties such as size, density and compressibility. Acoustophoresis holds great promise as a cell separation technique in several research and clinical areas. However, it has been suggested that the force acting upon cell
Massive MIMO, also known as very-large MIMO or large-scale antenna systems, is a new technique that potentially can offer large network capacities in multi-user scenarios. With a massive MIMO system, we consider the case where a base station equipped with a large number of antenna elements simultaneously serves multiple single-antenna users in the same time-frequency resource. So far, investigatio
Lactococcus garvieae is a rare cause of infective endocarditis (IE) in humans and the bacterium can easily be misidentified. Intracranial haemorrhage often occurs in conjunction with IE, but subdural haemorrhage (SDH) is very rarely encountered.
We aim to provide a long-term ecological analysis of land-use and floristic diversity in the transition from traditional to modern land-use management in the time a.d. 1800-2008 in southern Sweden. We use the Regional Estimates of Vegetation Abundance from Large Sites (REVEALS) model to quantify land-cover changes on a regional scale at 20-year intervals, based on the fossil pollen record. Florist
