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Aim To investigate the association of temperature on arrival to hospital after out-of-hospital-cardiac arrest (OHCA) with the primary outcome of mortality, in the targeted temperature management (TTM) trial. Methods The TTM trial randomized 939 patients to TTM at 33 or 36 °C for 24 h. Patients were categorized according to their recorded body temperature on arrival and also categorized to groups o

Many critics have noted Ah Cheng’s extensive use of Daoist imagery and symbolism in his novella King of Chess from 1984. The story refers directly to Daoist discourse of non-action (无为wuwei) and the power of yielding/softness in its treatment of the Chinese Way (道dao) of chess, and thus readings have focused on the metaphysical aspects of Daoism. Chess, however, is only one of the two great passio

In particular, I look at how traces of Zhuangzi’s butterfly dream appear in the oneiric fictions of Argentinian writer Jorge Luis Borges, and how, in turn, Borges’ dream-worlds have inspired Chinese author Can Xue to create a new kind of literary dreamscape.

Inspired by cultural geographer David Crouch’s description of heritage as a journey,3 this paper looks at how the narrator’s physical and mental voyage towards the old capital of her childhood incorporates multiple spatiotemporal layers of urban cultural heritage in order to reach a deeper understanding of the living historical city she calls home.

In the works of Can Xue, houses and buildings act as the outer shell of the fragile self. Her depiction of these uncanny places of inhabitance questions the rationalist notion of an objective border between self and surroundings, paving the way for a subjective and phenomenological approach to reality.

The Biopython Project is a long-running distributed collaborative effort, supported by the Open Bioinformatics Foundation, which develops a freely available Python library for biological computation.We present here details of the latest Biopython release - version 1.66. New features include: extended Bio.KEGG and Bio.Graphics modules to support drawing KEGG pathways with transparency; extended “ab

Type 2 diabetes is characterized by hyperglycemia due to insulin resistance in the target tissue and insufficient insulin secretion from the beta cells. Finding new mechanisms and pathways involved in the regulation of insulin secretion from the pancreatic beta cells is of great importance. Our group has earlier found, miRNA-212 and miRNA-132 to be upregulated in the non-obese type 2 diabetic GK r

Biogenic Volatile Organic Compounds (BVOCs) are trace gases other than CO2 and CH4 produced and emitted by the biosphere, where the amounts released depend on climatic factors such as temperature and solar irradiation. However, interpretation of leaf-level measurements is currently hampered by factors such as large within-genotypic variability, measurement height and time in the season. A campaign

In recent decades studies based on questionnaires and interviews have concluded that when doctors become ill they face significant barriers to seeking help. Several reasons have been proposed, primarily the notion that doctors' work environment predisposes them to an inappropriate help-seeking behaviour. In this article, the idea of the ill physician as a paradox in a medical drama is examined. Th