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BACKGROUND: Mechanisms regulating the ABO gene are unclear, especially in the hematopoietic compartment. The number of 43-bp repeats in the CBF/NF-Y-binding enhancer region is considered to have a major influence on transcription. STUDY DESIGN AND METHODS: Transcript levels in peripheral blood and in erythropoietic culture of CD34+ cells from marrow donors were measured with TaqMan assays. The 5'-

Objective To investigate if the prediction of malignant adnexal masses can be improved by considering different ultrasound-based subgroups of tumors and constructing a scoring system for each subgroup instead of using a risk estimation model applicable to all tumors. Methods We used a multicenter database of 1573 patients with at least one persistent adnexal mass. The masses were categorized into

In this paper, we consider the bootstrap procedure for the augmented Dickey-Fuller (ADF) unit root test by implementing the modified divergence information criterion (MDIC, Mantalos et al. [An improved divergence information criterion for the determination of the order of an AR process, Commun. Statist. Comput. Simul. 39(5) (2010a), pp. 865-879; Forecasting ARMA models: A comparative study of info

The aim is to review a patented method and apparatus for treating tumor diseases (cancer) with a combination of ionizing radiation and pulsed electric fields, that might open a new regime of radiation therapy fractionation with a short intensive treatment with high radiation dose fractions combined with pulsed electric fields. Sub-optimal radiation treatment was administered separately or in combi

Triple-negative breast cancers are an aggressive subtype of breast cancer with poor survival, but there remains little known about the etiologic factors that promote its initiation and development. Commonly inherited breast cancer risk factors identified through genome-wide association studies display heterogeneity of effect among breast cancer subtypes as defined by the status of estrogen and pro

Aim: The aim of this study was to describe asylum seekers' satisfaction with daily occupations and activity level while in a Danish asylum centre, and whether this changed over time. Another aim was to describe whether exposure to torture, self-rated health measures, and ADL ability were related to their satisfaction with daily occupations and activity level. Methods: A total of 43 asylum seekers

This issue of RIG has its starting point in a colloqium in Stockholm, held in october 2008 concerning the futures av ethnology. The participants discussed several problems and opportunities. One problem is fewer and fewer applications to basic education, another the question of employability. Ethnologists are well suited for different jobs but we have difficulties communicating it. On the other ha

Urinary cadmium (U-Cd) sampling can be done either by 24-h urine or spot urine sampling, and adjustment for dilution is usually needed. The choice of sampling period and adjustment technique could, however, potentially induce bias. The aim of the study was to compare 24-h urine and spot urine sampling and two dilution adjustment techniques, when assessing U-Cd. Separate 24-h urine (U24) and timed

Popular Abstract in Swedish Ungefär 22 000 svenskar lever i dag med Parkinsons sjukdom som är en hjärnsjukdom där särskilda nervceller som normalt producerar signalsubstansen dopamin dör av okänd anledning. Dessa nervceller har en viktig funktion eftersom de möjliggör vår rörelseförmåga och brist på dopamin leder till rörelsenedsättning där patienten uppvisar symptomen långsamhet, skakningar, muskParkinson’s disease is a brain disorder characterized by loss of dopaminergic neurons in the midbrain, resulting in the characteristic motor symptoms: resting tremor, rigidity, akinesia and postural instability. Symptomatic treatment is based on reconstituting the loss of dopamine in the brain, primarily by oral administration of its precursor L-DOPA. Although this drug is effective in the early y

Popular Abstract in Swedish I denna avhandling ges en introduktion till fyra artiklar där resul- tat från och delar av en frielektron-laser (FEL) beskrivs. Denna typ av laser skiljer sig från de konventionella lasrar de flesta av oss har träffat på, t.ex. i form av en laserpekare. Den första märkbara skill- naden är att frielektron-lasrar är stora, ofta flera hundra meter långa. De kräver en accelThe test free-electron laser (test-FEL) at MAX-lab in Lund demonstrated for the first time circularly polarized coherent femtosecond pulses at 66 nm wavelength. A 375 MeV electron bunch was seeded by a femtosecond laser at 263 nm and coherent harmonics were extracted in an APPLE-II type elliptical undulator. A thermionic gun with a barium oxide cathode was adapted for photocathode operation, and t

This paper extends the concept of weak renegotiation-proof equilibrium (WRP) to allow for costly renegotiation and shows that even small renegotiation costs can have dramatic effects on the set of equilibria. More specifically, the paper analyzes the infinitely repeated Bertrand game. It is shown that for every level of renegotiation cost, there exists a discount factor such that any collusive pro

Background: Epidemiological studies that assess the health effects of long-term exposure to ambient air pollution are used to inform public policy. These studies rely on exposure models that use data collected from pollution monitoring sites to predict exposures at subject locations. Land-use regression (LUR) and universal kriging (UK) have been suggested as potential prediction methods. We evalua

Objectives. A family history of prostate cancer is associated with a higher risk for prostate cancer to first-degree relatives. If greater surveillance of men at familial risk is considered to be useful, population-based estimates of the differences in the age at diagnosis between familial and sporadic prostate cancer cases are needed. Methods. The men in the nationwide Swedish Family-Cancer Datab

Using electron spectroscopy, we have investigated nanoplasma formation from noble gas clusters exposed to high-intensity hard-x-ray pulses at ~5 keV. Our experiment was carried out at the SPring-8 Angstrom Compact free electron LAser (SACLA) facility in Japan. Dedicated theoretical simulations were performed with the molecular dynamics tool XMDYN. We found that in this unprecedented wavelength reg

Objective. The purpose of the present analysis was to analyze and compare the cost-effectiveness of solifenacin flexible dosing (5-10 mg) with tolterodine 4 mg sustained release (SR) or placebo (assumed to be comparable to no treatment) for patients with overactive bladder (OAB) symptoms. Design. A decision-analytic model was constructed. Methods. Costs and effects were evaluated for the three tre