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Monomeric and dimeric cyclomaltodextrinases reveal different modes of substrate degradation

Two cyclomaltodextrinases (CDase) of thermophilic origin were investigated for their action on cyclodextrins. Although most CDases known today are made up of at least homodimers, one of the enzymes studied was shown to be a monomer in solution, while the other one was a dimer. Interestingly, the dimeric enzyme had a much superior selectivity for a cyclodextrin substrate compared to its monomeric h

Subcutaneous fat accumulation and BMI associated with risk for pulmonary embolism in patients with proximal deep vein thrombosis: a population study based on 23,796 consecutive autopsies

Objective. Although deep vein thrombosis (DVT) and pulmonary embolism (PE) are manifestations of the same disease, far from all patients develop PE. Our objective was to investigate risk-modifying factors. Setting, subjects and design. Between 1970 and 1982, 23 796 autopsies, representing 84% of all in-hospital deaths in the Malmo City population, were performed, using a standardized procedure. In

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Historical archaeology in the present : Personal reflections on the subject, now that medieval archaeology at Lund University from January 2005 has been transformed into an historical archaeology.

Valence photoionization and resonant core excitation of ozone - experimental and theoretical study of the (C)over-tilde-state of O-3(+)

Resonant Auger electron spectra of core excited O-3 (O(F)1s(-1) 2b(1)(1)) are presented for the first time. The photoionization valence spectrum with sample purity and resolution superior to those published is presented. The first direct experimental evidence for the (C) over tilde (2) B-1 state of O-3(+) is found. Ab initio calculations of the resonant Auger electron (RAE) spectrum have been perf

Heavy quark photoproduction in ultraperipheral heavy ion collisions

Heavy quarks are copiously produced in ultraperipheral heavy ion collisions. In the strong electromagnetic fields, c (c) over bar and b (b) over bar are produced by photonuclear and two-photon interactions. Hadroproduction can also occur in grazing interactions. We calculate the total cross sections and the quark transverse momentum and rapidity distributions, as well as the Q (Q) over bar invaria

Actomyosin motility on nanostructured surfaces

We have here, for the first time, used nanofabrication techniques to reproduce aspects of the ordered actomyosin arrangement in a muscle cell. The adsorption of functional heavy meromyosin (HMM) to five different resist polymers was first assessed. One group of resists (MRL-6000.1XP and ZEP-520) consistently exhibited high quality motility of actin filaments after incubation with HMM. A second gro

Factors influencing the response to interferon therapy in chronic hepatitis C. Studies on viral genotype and induction of 2',5'-oligoadenylate synthetase in the liver and peripheral blood cells

BACKGROUND: The mechanism behind the antiviral action of interferon (IFN) therapy in chronic hepatitis C virus (HCV) infection is not well understood, and, furthermore, few factors have been shown to be good predictors of a favourable response to IFN treatment in chronic HCV infection. METHODS: Freshly explanted liver cells and peripheral blood mononuclear cells (PBMC) from 80 patients with chroni

Blood flow velocity in the uterine and ovarian arteries during menstruation

Eleven healthy women with regular menstrual cycles were examined with a combination of two-dimensional real-time ultrasound and color and spectral Doppler techniques on the 7th day after follicular rupture, and on the 1st, 2nd, 3rd and 4th days of menstrual bleeding. Both uterine arteries, arteries in the stroma and hila of both ovaries, in the wall of the largest follicle of the non-dominant ovar

Constructing Evolutionary Trees - Algorithms and Complexity

In this thesis three general problems concerning construction of evolutionary trees are considered. Algorithms for the problems are presented and the complexity of the problems is investigated. The thesis consists of three corresponding parts. The first part is devoted to the problem of constructing evolutionary trees in the experiment model. Different algorithms for the problem are given, includ

Prevention of thrombosis following deep arterial injury in rats by bovine activated protein C requiring co-administration of bovine protein S.

The antithrombotic effect of bovine activated protein C (bAPC) given with or without bovine protein S (bPS) was investigated in a rat model of deep arterial injury. A segment of the left common carotid artery was isolated between vascular clamps and opened longitudinally. An endarterectomy was performed and the arteriotomy was closed with a running suture, whereafter the vessel was reperfused by r

Control of oral closure in lingual stop consonant production

Previous work has shown that the lips are moving at a high velocity when the oral closure occurs for bilabial stop consonants, resulting in tissue compression and mechanical interactions between the lips. The present experiment recorded tongue movements in four subjects during the production of velar and alveolar stop consonants to examine kinematic events before, during, and after the stop closur

On the codimension of the range of a composition operator

Let $\Omega$ be a domain in ${\bf C}$. A point $\lambda$ of the boundary of $\Omega$ is said to be essential if, for every neighborhood $V$ of $\lambda$, there is an $f\in H^\infty(\Omega)$ such that $f$ does not extend analytically to $V$. It is known that there is a smallest domain $\Omega^*$ containing $\Omega$ such that $\Omega^*$ has no nonessential boundary points. The main result here is th

Some Applications of Variational Inequalities in Mathematical Finance and Numerics

This thesis contains two parts. The first part deals with a stochastic impulse control problem, subject to the restriction of a minimum time lapse in between interventions made by the controller. We prove existence of an optimal control and show that the value function of the control problem satisfies a system of quasi-variational inequalities. Furthermore, we apply the control method to pri

How can cooperation between rehabilitation professionals in rehabilitation planning be improved? A qualitative study from the employer's perspective.

Research shows that there are often problems with cooperation between rehabilitation professionals within vocational rehabilitation. The aim of this study was to describe employers' experiences of how cooperation between different rehabilitation professionals can be improved in a vocational rehabilitation planning process. Ten employers who had sent their employees to vocational rehabilitation at