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Validation of the Skåne University Hospital nomogram for the preoperative prediction of a disease-free axilla in patients with breast cancer

BACKGROUND: Axillary staging via sentinel lymph node biopsy (SLNB) is performed for clinically node-negative (N0) breast cancer patients. The Skåne University Hospital (SUS) nomogram was developed to assess the possibility of omitting SLNB for patients with a low risk of nodal metastasis. Area under the receiver operating characteristic curve (AUC) was 0.74. The aim was to validate the SUS nomogra

IKT! and Łukasiewicz-models

In this note, we show that the first-order logic IK! is sound with regard to the models obtained from continuum-valued Łukasiewicz-models for first-order languages by treating the quantifiers as infinitary strong disjunction/conjunction rather than infinitary weak disjunction/conjunction. Moreover, we show that these models cannot be used to provide a new consistency proof for the theory of truth

Importance of patellofemoral and tibiofemoral cartilage lesions on trajectory of self-reported outcomes in patients at high risk of knee OA : 4–6 years follow-up of patients undergoing meniscal surgery

Objective: We evaluated whether patient-reported outcome trajectories (i.e., changes over time) differed by intraoperative compartmental cartilage lesion pattern over 4–6 years following arthroscopic meniscal surgery. Methods: In this ancillary study of the Knee Arthroscopy Cohort Southern Denmark cohort, we intraoperatively categorized cartilage lesions as isolated patellofemoral, isolated tibiof

Metastability phenomena in two-dimensional rectangular lattices with nearest-neighbour interaction

We study analytically the dynamics of two-dimensional rectangular lattices with periodic boundary conditions. We consider anisotropic initial data supported on one low-frequency Fourier mode. We show that, in the continuous approximation, the resonant normal form of the system is given by integrable PDEs. We exploit the normal form in order to prove the existence of metastability phenomena for the

How Surface Species Drive Product Distribution during Ammonia Oxidation : An STM and Operando APXPS Study

The oxidation of ammonia is a key reaction for the production of artificial fertilizers and for environmental protection. Depending on the area of application, the catalytic reaction needs to be tuned toward the production of either N2 or NO, and this selectivity is controlled by temperature, pressure, reactant ratio, and the type of catalyst. PtRh alloys are highly useful catalytic materials for

Tailoring plasmonic resonances in Cu-Ag metal islands films

The plasmonic response of Cu-Ag metal islands films is investigated. Films are obtained by subsequent electron beam deposition of Ag and Cu using different fabrication conditions: deposited mass thickness, substrate temperature and post-deposition annealing in vacuum. Optical properties of films are investigated by spectroscopic ellipsometry and correlated with the structural characterization resu

Large screen enabled tri-port MIMO handset antenna for low LTE bands

In recent years, the screen-to-body ratio of mobile handsets has been increasing. Today, the screen nearly fills up the entire front side. Conventionally, the screen is mainly seen as a metallic object that adversely affects antenna performance. In this paper, the large screen is used for the first time to facilitate an additional uncorrelated MIMO port in a tri-port design, for several LTE bands

A world of innumberable inactivities Martin Hägglund and the economy of non-existence

This essay challenges Martin Hägglund's interpretation of the hope of immortality as a longing for death and his identification of life with survival. It does so by interpreting the epitaph of the charwoman, which John Maynard Keynes refers to in "Economic Possibilities for our Grandchildren", as an eschatological speculation on what the dead are doing in the afterlife. The epitaph expresses a sab

The Pan African Vivax and Ovale Network (PAVON) : Refocusing on Plasmodium vivax, ovale and asymptomatic malaria in sub-Saharan Africa

The recent World Malaria report shows that progress in malaria elimination has stalled. Current data acquisition by NMCPs depend on passive case detection and clinical reports focused mainly on Plasmodium falciparum (Pf). In recent times, several countries in sub-Saharan Africa have reported cases of Plasmodium vivax (Pv) with a considerable number being Duffy negative. The burden of Pv and Plasmo

Toward the equilibrium and kinetics of amyloid peptide self-assembly

Several devastating human diseases are linked to peptide self-assembly, but our understanding their onset and progression is not settled. This is a sign of the complexity of the aggregation process, which is prevented, catalyzed, or retarded by numerous factors in body fluids and cells, varying in time and space. Biophysical studies of pure peptide solutions contribute insights into the underlying

Dynamical evolution of two planet systems into the white dwarf phase

In this contribution we present some preliminary results on the dynamical evolution of two planet systems around stellar hosts evolving from the main sequence to the white dwarf phase. The aim is to study the instabilities triggered by stellar evolution that may bring planets onto the stellar surface or produce planetary scale collisions (hence debris) that could explain the metallic atmospheric p

Disseminated tumour cells from the bone marrow of early breast cancer patients : Results from an international pooled analysis

Purpose: Presence of disseminated tumour cells (DTCs) in the bone marrow (BM) has been described as a surrogate of residual disease in patients with early breast cancer (EBC). PADDY (Pooled Analysis of DTC Detection in Early Breast Cancer) is a large international analysis of pooled data that aimed to assess the prognostic impact of DTCs in patients with EBC. Experimental design: Individual patien

A Guide for Using Flight Simulators to Study the Sensory Basis of Long-Distance Migration in Insects

Studying the routes flown by long-distance migratory insects comes with the obvious challenge that the animal’s body size and weight is comparably low. This makes it difficult to attach relatively heavy transmitters to these insects in order to monitor their migratory routes (as has been done for instance in several species of migratory birds. However, the rather delicate anatomy of insects can be

A comparative study of the effects of the 1872 storm and coastal flood risk management in denmark, germany, and sweden

From November 12th to 13th in 1872, an extreme coastal flood event occurred in the south Baltic Sea. An unusual combination of winds created a storm surge reaching up to 3.5 m above mean sea level, which is more than a meter higher than all other observations over the past 200 years. On the Danish, German, and Swedish coasts, about 300 people lost their lives. The consequences of the storm in Denm

Locating potential sources of capacity and vulnerability in geographically remote areas : Reflections based on three case studies

The relationship between geographical and social forms of remoteness and the concepts of vulnerability and capacity remains unclear. Recognising that capacities and vulnerabilities tend to co-exist in a population, the article assumes that the dynamics between these concepts are situational. In this article we draw on three cases to analyse the issue. An Arctic case study provides insight on remot

Homeostatic swimming of zooplankton upon crowding : The case of the copepod Centropages typicus

Crowding has a major impact on the dynamics of many material and biological systems, inducing effects as diverse as glassy dynamics and swarming. While this issue has been deeply investigated for a variety of living organisms, more research remains to be done on the effect of crowding on the behaviour of copepods, the most abundant metazoans on Earth. To this aim, we experimentally investigate the

Decadal-scale dune evolution at Duck, North Carolina

Analysis of a 13-year long, high-resolution data series on beach profiles, surveyed from 1981 to 1993 by the Army Field Research Facility (FRF) at Duck, North Carolina, in the United States, was analyzed in order to understand the temporal and spatial characteristics of the dune response. Various statistical methods were employed in this analysis. The profile survey data set was analyzed with rega