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Intrajejunal Levodopa Versus Conventional Therapy in Parkinson Disease: Motor and Nonmotor Effects.

ABSTRACT: Seventeen patients with advanced Parkinson disease (PD) were treated with intrajejunal L-dopa infusion (IJL) and compared with a matched group of 9 patients (termed comparator [C]) not given IJL because of funding restriction by primary care trusts (PCTs) in the UK, although considered to be clinically eligible for IJL. Assessments were baseline and follow-up (6 months) with Hoehn and Ya

Using simulation for assessing the real impact of test-coverage on defect-coverage

The use of test-coverage measures (e.g., block-coverage to control the software test process has become an increasingly common practice. This is justified by the assumption that higher test-coverage helps achieve higher defect-coverage and therefore improves software quality. In practice, data often show that defect-coverage and test-coverage grow over time, as additional testing is performed. How

The Neuroanatomic Localization of Epstein-Barr Virus Encephalitis May Be a Predictive Factor for Its Clinical Outcome: A Case Report and Review of 100 Cases in 28 Reports.

Encephalitis is one of the manifestations of infection with Epstein-Barr virus with clinical outcome varying from complete recovery to death. A 16-year-old boy with Epstein-Barr virus encephalitis with global cortical and subcortical gray matter involvement and a full clinical recovery is reported. The case inspired a literature review which yielded 100 cases of Epstein-Barr virus encephalitis sub

Nattsänkning - analys av en onödig komplikation

Med en enkel dynamisk modell analyseras nattsänkning. Författaren drar slutsatserna att nattsänkning ger små besparingar som också kan uppnås genom sänkning av framledningstemperaturen, vidare att nattsänkning och dag/nattaxa är i konflikt med varandra.

Retail and fashion - A happy marriage? The making of a fashion industry research design

Fashion and retail ought to be a happy marriage. Yet several entrepreneurs in the field of fashion speak of a climate that is difficult to penetrate because of economic and cultural factors. For example, the chain store concept is an expression of the specific and current fashion situation in Sweden: democratic fashion that is cheap and accessible. At the same time, customers now demand personal,

Deregulation of the Wilms' tumour gene 1 protein (WT1) by BCR/ABL1 mediates resistance to imatinib in human leukaemia cells

The Wilms' tumour gene 1 (WT1) protein is highly expressed in most leukaemias. Co-expression of WT1 and the fusion protein AML1-ETO in mice rapidly induces acute myeloid leukaemia (AML). Mechanisms behind expression of WT1, as well as consequences thereof, are still unclear. Here, we report that the fusion protein BCR/ABL1 increases expression of WT1 mRNA and protein via the phosphatidylinositol-3

Quasi-resonant Energy-transfer In Collisions - Na2(a(1)sigma(u)(+))+k(4s)

Cross sections for electron energy transfer from the initial rotational state J' of the two lowest vibrational levels upsilon' = 0 and upsilon' = 1 of excited dimers Na2(A) to potassium atoms as described by Na2(A1Sigma(u)+, upsilon'J') + K(4S) --> Na2 (X1Sigma(g)+, upsilon''J'')+K(4P)+DeltaE have been examined by laser-induced fluorescence. A strong increase of the cross section by as much as an

Konsten att öppna för konversation

Konsthistorikern Grant Kester har formulerat en dialogisk estetik som tar fasta på konsten som en öppen, kollektiv sfär. I boken ”Conversation pieces” lyfter han fram konstnärer och filosofer som beskrivit eller förverkligat konsten som en dialog.

Tribute to a great obstetrician: in memory of Ingemar Ingemarsson.

Ingemar Ingemarsson, grew up in a rural area in Småland in the southern part of Sweden. He studied and graduated at the Medical Faculty at Lund University and started his career in obstetrics and gynecology in 1972 at the University Hospital in Lund. He defended his PhD thesis in 1975, was appointed consultant and later became Head of the Department and Professor in Obstetrics at Lund University.

Frequency estimation from crossings of an observed mean level

By counting the number of upcrossings of the mean level by a stationary Gaussian process one can estimate the mean frequency of the process. If the mean level is unknown and estimated from the observed mean level, then this crossing estimator is more or less biased, depending on the length of the observation interval. It is shown that if the interval is at least two mean wavelengths, then the bias

Depersonalization disorder may be related to glutamate receptor activation imbalance.

Low-dose ketamine administration mimics, both clinically and on gross neuroimaging, depersonalization disorder. The perceptual effects of ketamine may be due to secondary stimulation of glutamate release and lamotrigine, possibly by inhibited glutamate release, may reduce some of ketamine's so-called dissociative effects. However, lamotrigine does not seem to be useful in the treatment of deperson