OBJECTIVE: To explore the relationships between C-reactive protein (CRP), metabolic syndrome (MetS) and incidence of severe knee or hip osteoarthritis (OA) in a prospective study. METHODS: A population-based cohort (n=5171, mean age 57.5+/-5.9 years) was examined between 1991 and 1994. Data was collected on lifestyle habits, measures of overweight, blood pressure as well as high-density lipoprotei

An improved conventional-to-micro/minichannel criterion was proposed by using the Bond number and the liquid Reynolds number. In micro/minichannels, bubbles tend to be confined and elongated in the channel and the conventional two-phase flow theory loses its applicability. As significant disagreement in experimental trends and heat transfer mechanisms was reported for flow boiling in micro/minicha

Madelung A, Bzorek M, Bondo H, Zetterberg E, Bjerrum O W, Hasselbalch H C, Scheding S & Ralfkiaer E (2012) Histopathology A novel immunohistochemical sequential multi-labelling and erasing technique enables epitope characterization of bone marrow pericytes in primary myelofibrosis Aim: In Philadelphia (Ph)-negative chronic myeloproliferative neoplasms, increased microvascular density, bizarre

BACKGROUND: Among head and neck cancers, human papillomavirus type 16 (HPV16) is associated with tonsillar carcinomas. Despite this, no HPV16-positive tonsillar cancer cell line has been established in nude mice.METHODS: Fresh tonsillar carcinoma biopsies were obtained from 23 patients and implanted subcutaneously into nude mice (BALB/c, nu/nu).RESULTS: After 7 months, one xenograft was establishe

OBJECTIVE: To use self-reported disability (Roland-Morris Disability Questionnaire [RMDQ]) to assess the criterion validity of straight leg raising (SLR) test and flexion range of motion (ROM) (fingertip-to-floor test) before and after stratification by sex and presence/absence of radicular pain. DESIGN: Cross-sectional study. SETTING: Outpatient physical therapy clinic. PARTICIPANTS: Subjects wit

The idea to use transplants of dopamine-producing cells to substitute for the lost midbrain dopamine neurons in Parkinson's disease (PD) goes back to the 1970s. In this review we give an overview of the history of cell transplantation in animal models of PD, and summarize the experience gained from the open-label and placebo-controlled clinical trials performed so far using intrastriatal transplan

Three experiments were conducted to investigate the impact of affect on moral judgment. Participants read stories describing morally questionable actions and made judgments of wrongness. Judgments were affected by morally irrelevant disgust, and the effect was moderated by individual differences in disgust sensitivity and preferred processing mode. More specifically, the effect was stronger for pa

The purpose of this thesis is double. First, it will be shown that a number of problems of the syntax of ancient, literary Italian lend themselves readily to an analysis in terms of the Theory of Principles and Parameters. Second, the Italian data, supported by comparative remarks on modern Romance and Germanic, confirm the essential correctness of one particular version of the above theory namely

Analys av två Greta Garbo-filmer. Del två i en serie om två om Greta Garbos filmstjärneimage.

The process of change has been considered within many areas of contemporary thinking. Consequently, many aspects of change have been explored through different theoretical angles. Using insights from 'translation' theory, this article considers critical factors that affect cross-sectoral networking process for SD-a popular form of collaboration. The empirical data for this study comes from the inv

Researchers from various disciplines have been pursuing better understanding of learning and forgetting processes. A range of mathematical models, sometimes based on empirical data, has been developed to measure the effect of production breaks on the learning process. Thus far, researchers and practitioners have not resolved the issue of how learning and forgetting interacts. However, some of the

A novel surface protein of the bacterial species Moraxella catarrhalis that displays a high affinity for IgD (MID) was solubilized in Empigen and isolated by ion exchange chromatography and gel filtration. The apparent molecular mass of monomeric MID was estimated to approximately 200 kDa by SDS-PAGE. The mid gene was cloned and expressed in Escherichia coli. The complete mid nucleotide gene seque

BACKGROUND: Staurosporine is a therapeutic agent that inhibits tumor cell growth by inducing cell death via intrinsic apoptotic pathways. Our previous studies in clinical settings have suggested that certain subpopulations of patients with acute myeloid leukemia (AML) had poor response to chemotherapy. MATERIALS AND METHODS: The effect of staurosporine on apoptosis and cell cycle distribution in h

PURPOSE: It is unknown whether childhood cancer and its treatment are associated with sperm DNA damage, which subsequently affects fertility and might be transmitted to the offspring. The aim of this study was to assess DNA fragmentation index (DFI) as an indicator of sperm DNA integrity in childhood cancer survivors (CCS), treatment regimen taken into account.EXPERIMENTAL DESIGN: In 99 CCS and 19

The current study aimed to characterize changes in EEG-related measures after noxious stimuli in neonates, and to assess their potential utility as measures of pain and/or discomfort during neonatal intensive care.Seventy-two healthy term infants were investigated: Twenty-eight had a non skin-breaking pin-prick on the heel, randomized to receive either oral glucose (n=16) or water (n=12) before th

In this study, we investigated how prolonged consumption of sugar solution affects hippocampal neurogenesis. We gave rats sucrose or fructose solution for four weeks and observed a 40% reduction in BrdU/NeuN-immunoreactive cells in the hippocampal dentate gyrus. This reduction in hippocampal neurogenesis was accompanied by increased apoptosis in the hippocampus and increased circulating levels of