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Design and manufacturing of an electric vehicle for car-sharing in Bogotá

Car-sharing systems with electric vehicles are an alternative to reduce commuting times in big cities and also to mitigate air pollution. Car-sharing exists in 1100 cities around the world. These systems have had positive effects in the cities, replacing between 9 and 23 private vehicles for each car. This document proposes a public car-sharing system for Bogotá. The article focuses on the design

Fresh pipes with dirty water: How quality of government shapes the provision of public goods in democracies

A large strand of research holds that democracy with its broad representation and electoral accountability is beneficial for the provision of public goods. Yet, there is a large variation in how democracies perform, indicating that democratic institutions alone do not suffice for securing citizens’ wellbeing. Recent studies have stressed the equal importance of state capacity for public goods deli

Radial band bending at wurtzite–zinc-blende–GaAs interfaces

The band offset between wurtzite (wz) and zinc-blende (zb) GaAs is an important fundamental parameter in polytype heterostructure engineering. Since the interface has a type-II band alignment, it is reasonably straightforward to measure the band offset using photoluminescence (PL) e.g. on nanowires containing heterostructures between wz and zb GaAs. It has, however, been found that the transition

Emission enhancement, light extraction and carrier dynamics in InGaAs/GaAs nanowire arrays

Nanowires (NWs) have the potential for a wide range of new optoelectronic applications. For example, light-emitting diodes that span over the whole visible spectrum are currently being developed from NWs to overcome the well known green gap problem. However, due to their small size, NW devices exhibit special properties that complicate their analysis, characterization, and further development. In

Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death

Mutations of Fused in sarcoma (FUS), a ribonucleoprotein involved in RNA metabolism, have been found associated with both familial and sporadic cases of amyotrophic lateral sclerosis (ALS). Notably, besides mutations in the coding sequence, also mutations into the 3′ untranslated region, leading to increased levels of the wild-type protein, have been associated with neuronal death and ALS patholog

Global parameters sensitivity analysis of modeling water, energy and carbon exchange of an arid agricultural ecosystem

Agricultural ecosystems are important for regulating terrestrial hydrological and carbon cycles. Hydrological and carbon processes in agricultural ecosystem models are complex due to interactions between parameters. It is therefore crucial to identify parameter sensitivity before a process-based model is applied for simulations and predictions of water, energy and carbon fluxes in agricultural ec

Performance of Bio-Rad HIV-1/2 Confirmatory Assay in HIV-1, HIV-2 and HIV-1/2 dually reactive patients - comparison with INNO-LIA and immunocomb discriminatory assays

Background: Being able to discriminate between HIV-1, HIV-2 and HIV-1/2 dual infection is imperative for the appropriate selection of antiretroviral therapy (ART) in regions with high HIV-2 endemicity. Objectives: To evaluate Bio-Rad Geenius HIV-1/2 Confirmatory Assay against INNO-LIA HIV 1/2 Score and ImmunoComb HIV 1/2 BiSpot with an emphasis towards ability to discriminate between HIV-1, HIV-2

Rational targeting of population groups and residential areas for colorectal cancer screening

Background: Sociodemographic and spatial disparities in incidence and mortality burden of colorectal cancer (CRC) are important to consider in the implementation of population screening, in order to achieve expected benefit and not increase health inequities. Analytic methods should be adapted to provide rational support for targeted interventions. Methods: CRC incidence rates by tumor stage (I-IV