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Affibody molecules are small scaffold-based affinity proteins with promising properties as probes for radionuclide-based molecular imaging. However, a high reabsorption of radiolabeled Affibody molecules in kidneys is an issue. We have shown that the use of (125)I-3-iodo-((4-hydroxyphenyl)ethyl)maleimide (IHPEM) for site-specific labeling of cysteine-containing Affibody molecules provides high tum

BACKGROUND: Lateral ankle sprain (LAS) is a common and burdensome injury. However, the quality of its management is scant. Nowadays, physiotherapy management of musculoskeletal diseases seems to be generally not based on research evidence. Studies that investigated the knowledge-to-practice gap in LAS management are yet to be carried out. Therefore, this research investigated physiotherapists' kno

This paper provides a comprehensive literature review of preliminary publications on green and sustainable public procurement from the year 2000 until now. The aim of the review is to organise, evaluate and identify patterns and clusters in published articles, providing an overview of the state of the art in green and sustainable public procurement. Classification of the data identified three over

Transitioning from linear to circular production systems requires interactions that include cross-sectoral collaboration in networks. Understanding the role of collaboration within these networks can support the transition to a circular economy. To understand cross-sectoral collaborative endeavors, this paper develops a collaboration framework for circular economy by combining and interlinking thr

Through ultrarelativistic particle collisions at the LHC, it is possible to deconfine quarks and gluons. This deconfinement gives rise to a strongly interacting medium, referred to as the Quark-Gluon Plasma (QGP). One of the earliest proposed and observed signatures of the QGP was the enhanced production of strange hadrons since the medium can thermally produce strange quarks. However, recent stud

Research shows that much of the blame for waste and lost resources can be traced to the design phase. The implementation of Circular Economy (CE) has the potential to reduce waste by encouraging reuse of resources in a closed loop. Given that designers are involved in the design process, this paper investigates whether they are properly equipped to take responsibility for the shift toward CE. A gr

The thesis aims to develop a 3D digital approach to the stylistic and typo-technological study of coroplastic, focusing on small figurines. The case study to test the method is a sample of terracotta statuettes from an assemblage of approximately 2000 statues and figurines found at the beginning of the 20th century in a rural open-air sanctuary at Ayia Irini (Cyprus) by the archaeologists of the S

In small systems with large fluctuations, the classical description of thermodynamics is no longer sufficient which has led to the development of stochastic thermodynamics. One important result from stochastic thermodynamics is that with measurement and feedback it is possible to use those fluctuations to extract work from a single heat bath coupled to the system. This is thanks to the connection

Organizing rural workers has always proved to be a challenge for the labour movement. This was especially the case in Scandinavia where well into the industrial era, labour and property relations in the agricultural countryside remained essentially feudal in character. Nonetheless, and especially in the rich agricultural districts of the southernmost province of Skåne, the Swedish labour movement

The Internet of Things (IoT) is a large network of connected devices. In IoT, devices can communicate with each other or back-end systems to transfer data or perform assigned tasks. Communication protocols used in IoT depend on target applications but usually require low bandwidth. On the other hand, IoT devices are constrained, having limited resources, including memory, power, and computational

Due to the large number of electrons, solid state physics boils down to many-body approximations in which only selected types of collective excitations are taken into account, guided by the emergent properties of the material under study. In this thesis, the collective excitations of primary interest are electronic charge and spin fluctuations(plasmons and magnons) and nuclear charge fluctuations

Materials of ionic crystals are ubiquitous in industrial chemistry.For example, materials such as cerium dioixde (CeO2) are used in both self-cleaning ovens and to clean exhaust fumes from cars.Other materials, such as titanium dioixde (TiO2) has been used in the solar-cell industry.So-called garnets are used in several lasers.In common for all of these areas of application, is that they are depen

Prior research has shown that companies in various industrial contexts need to achieve both exploitation of current knowledge and technologies to make profits today, and exploration of new knowledge and technologies to adapt to changing conditions and prepare for tomorrow’s demands. The capacity to achieve both exploration and exploitation is especially problematic in project based organizations d

This thesis investigates the role of artefacts in relation to human agency and design within a cognitive semiotics framework. It deals with questions such as What is agency? What are artefacts and how does agency relate to them? What kind of intentions are involved in the activity of designing? What is human-specific with respect to agency and design? How can the origins and evolution of design be

This is the final report of a three-year project called Building Egressibility in an Ageing Society, sponsored by the Swedish research council for sustainable development (FORMAS). While accessibility is an established and widely used concept in building design, the evacuation of people with functional limitations is still at a stage in which several research gaps exist. In this context, this work

Introduction and Aims: Up to 80% of adolescents have experienced trauma and one-in-seven suffer from post­ traumatic stress disorder (PTSD). For 50% of these adoles­cents, the course of their illness is further complicated by a co-occurring substance use disorder (SUD). Despite high rates of comorbidity, treatment options remain sparse and there is limited understanding of the clinical profile ass