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Treatment resistant depression (TRD) and suicidal behavior are among the most important public health problems and are commonly associated with significant disability and psychosocial impairment. Although there have been recent advances in identifying neurobiological correlates of these complex conditions, their pathophysiology still remains unclear. Although the recent advances concerning the neu

Ensuring sustainable consumption and production is one of the United Nations’ Sustainable Development Goals. Sustainable consumption can be supported through regulatory processes. Voluntary private regulatory schemes claiming to contribute to sustainability are a rapidly growing form of regulation. We study one such voluntary sustainability scheme in order to look at the opportunities and challeng

Everyday international political economy (EIPE) offers an opportunity to rethink the role of individuals and citizenry in shaping governance of natural resources. In South Africa, significant progress has been made by government in re-shaping water governance since the end of apartheid in the early 1990s. The role of government in water governance and water politics has thus been emphasised to a l

The past few decades have seen an increasing demand for environmental information on which to make more informed decisions, strengthened by several international calls for improving available environmental information. In a democratic South Africa, the involvement of people in policy and decision-making processes has led to an even greater need for accessible information. In response to this deman

From experience, it has been well known that the performance of IEEE 802.11 wireless local area networks significantly drops in dense settings, largely driven by poor capacity of the medium access control (MAC) layer. The current 802.11 MAC mechanism utilizes a contention window (CW) for random access, and the CW size is dictated to take discrete values from a bounded finite set. In this paper, wi

The study draws on findings from a series of seven participatory action research projects in community care for older people carried out over a period of eight years in 20 municipalities in southern Sweden. The analysis here looks at social impact across administrative levels and geographical scales. Different professional groups and care workers in community care participated, crossing divides be

Crop models are increasingly used to simulate crop yields at the global scale, but so far there is no general framework on how to assess model performance. Here we evaluate the simulation results of 14 global gridded crop modeling groups that have contributed historic crop yield simulations for maize, wheat, rice and soybean to the Global Gridded Crop Model Intercomparison (GGCMI) of the Agricultu

We present an open-source software platform that transforms emotional cues expressed by speech signals using audio effects like pitch shifting, inflection, vibrato, and filtering. The emotional transformations can be applied to any audio file, but can also run in real time, using live input from a microphone, with less than 20-ms latency. We anticipate that this tool will be useful for the study o

Recent years have seen an increasing number of biophysical studies of proteins being conducted in cells and concentrated protein solutions. In these experiments, compared to dilute-solution data, both stabilization and destabilization of globular proteins have been observed, which cannot be explained in terms of volume exclusion alone. For a fundamental understanding of the observed effects, there

Aims. This work reports new experimental radiative lifetimes and calculated oscillator strengths for transitions from 3d84d levels of astrophysical interest in singly ionized nickel. Methods. Radiative lifetimes of seven high-lying levels of even parity in Ni II (98 400-100 600 cm-1) have been measured using the time-resolved laser-induced fluorescence method. Two-step photon excitation of ions pr

Sepsis is a systemic immune response responsible for considerable morbidity and mortality. Molecular modeling of host-pathogen interactions in the disease state represents a promising strategy to define molecular events of importance for the transition from superficial to invasive infectious diseases. Here we used the Gram-positive bacterium Streptococcus pyogenes as a model system to establish a

A novel multi-jet burner was built to provide one-dimensional laminar flat flames with a wide range of variable parameters for multipurpose quantitative optical measurements. The burner is characterized by two independent plenum chambers, one supporting a matrix of 181 laminar jet flames and the other supporting a co-flow from a perforated plate with small holes evenly distributed among the jets.

We present a set of 87 RAVE stars with detected solar like oscillations, observed during Campaign 1 of the K2 mission (RAVE K2-C1 sample). This data set provides a useful benchmark for testing the gravities provided in RAVE data release 4 (DR4), and is key for the calibration of the RAVE data release 5 (DR5). The RAVE survey collected medium-resolution spectra (R = 7500) centred in the Ca II tripl

Aims. Spectral lines of He-like ions are among the most prominent features in X-ray spectra from a large variety of astrophysical and high-temperature fusion plasmas. A reliable plasma modeling and interpretation of the spectra require a large amount of accurate atomic data related to various physical processes. In this paper, we focus on the electron-impact excitation (EIE) process. Methods. We a

Teaching is present in all human societies, while within other species it is very limited. Something happened during the evolution of Homo sapiens that also made us Homo docens-the teaching animal. Based on discussions of animal and hominin learning, we analyze the evolution of intentional teaching by a series of levels that require increasing capacities of mind reading and communication on the pa