Colipase exists in pancreatic juice in a pro-form which is activated by limited trypsin hydrolysis. During this activation, the N-terminal pentapeptide 1Val-Pro-Asp-Pro-5Arg is cleaved. The new N-terminal sequence formed, 6Gly-Ile-Ile-Ile-10Asn, contains three isoleucine residues. The importance of these for stimulating lipase activity has been investigated by successive Edman degradation of epsil

Background & Aims: Evidence on the association between physical activity and risk of hepatobiliary cancers is inconclusive. We examined this association in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC). Methods: We identified 275 hepatocellular carcinoma (HCC) cases, 93 intrahepatic bile duct cancers (IHBCs), and 164 non-gallbladder extrahepatic bile duct cance

Lymphodepletion strategies are used in the setting of transplantation (including bone marrow, hematopoietic cell, and solid organ) to create space or to prevent allograft rejection and graft versus host disease. Following lymphodepletion, there is an excess of IL-7 available, and T cells that escape depletion respond to this cytokine undergoing accelerated proliferation. Moreover, this environment

A search for supersymmetry in events with large missing transverse momentum, jets, and at least one hadronically decaying τ-lepton is presented. Two exclusive final states with either exactly one or at least two τ-leptons are considered. The analysis is based on proton-proton collisions at s=13 TeV corresponding to an integrated luminosity of 36.1 fb-1 delivered by the Large Hadron Collider and re

Folkesundhed – bag om intentioner og strategier stiller skarpt på de eksisterende sundhedsforståelser i Danmark samt de rammer, tiltag og inventioner, som aktuelt udspiller sig med sigte på at styrke folkesundheden.Bogens hovedsigte er danne at grundlag for og inspiration til nuancerede og kritiske refleksioner over de aktuelle folkesundhedspraksisser og -strategier. Bogen belyser bl.a. medicinske

Fysisk aktivitet, eller motion, er en KRAM-faktor, der tænkes som bærende element for et sundt liv og en sund befolkning. Fysisk aktivitet sætter sig igennem i samfundet som noget, der er vigtigt at gøre, og. motion anvendes i stigende grad som forebyggende indsats og behandlingsform i det medicinske felt. Fysisk aktivitet indgår ofte som et element i sundhedsprofessionelles udviklingsprojekter, t

Normal differentiation and induced reprogramming require the activation of target cell programs and silencing of donor cell programs. In reprogramming, the same factors are often used to reprogram many different donor cell types. As most developmental repressors, such as RE1-silencing transcription factor (REST) and Groucho (also known as TLE), are considered lineage-specific repressors, it remain

BACKGROUND: Medical engagement is a mutual concept of the active and positive contribution of doctors to maintaining and enhancing the performance of their health care organization, which itself recognizes this commitment in supporting and encouraging high quality care. A Medical Engagement Scale (MES) was developed by Applied Research Ltd (2008) on the basis of emerging evidence that medical enga

En del barn får åka utomlands på semester. En del barn måste fly till ett annat land.På en flygplats står ett barn med sina föräldrar i världens längsta kö. Plötsligt syns ett annat barn som smyger omkring i kön. Äntligen! En kompis!Spelar det någon roll att man inte förstår varandras språk? Man kan ju leka i alla fall. Till exempel kurragömma. Kompisen är väldigt bra på att gömma sig!En del barn

Kapitlet behandlar läraryrkenas positioner och professionsstatus på utbildningens fält. Efter ett kort inledande avsnitt om fältet följer en översikt över svensk skolpolitik de senaste decennierna. Översikten fokuserar skolan och läraryrkenas samhälleliga inbäddning och förutsättningar efter skolverksamhetens kommunalisering och avreglering. Skolan som arbetsorganisation, rektorers framskjutna pos

We discuss three implementations of the CCFM evolution equations in event generator programs. We find that some of them are able to describe observables such as forward jet rates in DIS at HERA, but only if the so-called consistency constraint is removed. We also find that these results are sensitive to the treatment of non-singular terms in the gluon splitting function.

Energy security, climate change and air pollution are all motivations for further development of fuel cells. Still, technical problems relating to water management, continue to hinder the marketability of polymer electrolyte fuel cells (PEFCs). The impact of dynamic contact angle (CA) boundary conditions, according to the Kistler model, is evaluated in this paper with the VOF approach, focusing on

Changes in the inlet morphology of choked coastal lagoons often restrict the water exchange with the sea, making them vulnerable to pollution release and eutrophication processes. In this study, the role of tides for the water exchange was investigated in a choked lagoon for critical scenarios during the low river flow season. Both an integrated and spatially distributed approach were employed usi

This article discussed the history of the position of the married woman in Dutch personal income tax law in its historical, juridical en social-cultural background. From 1892-1984 married women were in fact tax transparent in the Netherlands