Filetype
This article investigates whether regime-based asset allocation can effectively respond to changes in financial regimes at the portfolio level in an effort to provide better long-term results when compared to a static 60/40 benchmark. The potential benefit from taking large positions in a few assets at a time comes at the cost of reduced diversification. The authors analyze this trade-off in a mul
Background: KIT mutations are the predominant driver mutations in gastrointestinal stromal tumors (GISTs), and targeted therapy against KIT has improved treatment outcome dramatically. However, gaining secondary mutation of KIT confers drug resistance of GISTs leading to treatment failure. Results: In this study, we found that secondary mutation of KIT dramatically increases the ligand-independent
Coronautbrottet är ett hot mot Sveriges nationella säkerhet. Det riskerar leda till en ökning av främmande makters aktiviteter, terrorattacker, organiserad brottslighet samt social oro, skriver Ardavan Khoshnood, specialistläkare, kriminolog och statsvetare.The corona eruption is a threat to Sweden's national security. It risks leading to an increase in the activities of foreign powers, terrorist attacks, organized crime and social unrest, writes Ardavan Khoshnood, specialist physician, criminologist and political scientist.
In my dissertation the method to describe semantic change used in the Swedish Academy dictionary (SAOB) is compared with cognitive semantic models of such a change. The work of SAOB is theoretically unbound in terms of overarching semantic theories, and the methods of describing word meaning and semantic change in the dictionary are rather developed for pragmatic reasons (such as consistency and e
Sustainability philosophers claim that we are at an impasse of stories, finding ourselves in a blank chapter between the old and the new. The old story, characterized by separation, technological dominance and human superiority over nature, is unfolding in an ecological crisis giving space for a new narrative defined by inter-being, cooperation and balance. It has been put forward that this crisis
Nature-based adaptation planning is a challenging endeavor, not least because it requires transdisciplinary approaches to unite different actors' efforts and capacities. However, empirical knowledge on associated governance processes is scarce and fragmented. Against this background, this paper examines the integration of nature-based approaches for climate change adaptation into municipalities’ d
