OBJECTIVES:We investigated if changes in serum/plasma fibrinogen (FIB), hyaluronan (HA) and cartilage oligomeric matrix protein (COMP) levels can be used to differentiate between inflammation and cartilage involvement during arthritis. METHODS:Collagen-induced arthritis (CIA), oil-induced arthritis (OIA) and for comparison, experimental autoimmune encephalitis (EAE) induced in DA rats were investi

The kinetics of furfural inhibition of the enzymes alcohol dehydrogenase (ADH; EC 1.1.1.1), aldehyde dehydrogenase (AlDH; EC 1.2.1.5) and the pyruvate dehydrogenase (PDH) complex were studied in vitro. At a concentration of less than 2 mM furfural was found to decrease the activity of both PDH and AlDH by more than 90%, whereas the ADH activity decreased by less than 20% at the same concentration.

BACKGROUND: Little work has been done to investigate the suggestion that the use of selected scales from a multi-scale health-status questionnaire would compromise reliability and validity. The aim of this study was to compare the performance of three scales selected from the SF-36 generic health questionnaire when administered in isolation or within the entire SF-36 to patients with musculoskelet

We show that measurements of time-varying mobile radio channels obtained with uncalibrated correlative channel sounders are affected by four different types of systematic errors (commutation, pulse-compression, aliasing, and misinterpretation error). We analyze these errors and provide upper error bounds that are formulated in terms of channel and sounder parameters. Based on these error bounds, w

We investigate the two-particle spin entanglement in magnetic nanoclusters described by the periodic Anderson model. An entanglement phase diagram is obtained, providing an important perspective on a central property of magnetic nanoclusters, namely, the temperature-dependent competition between local Kondo screening and nonlocal Ruderman-Kittel-Kasuya-Yoshida spin ordering. We find that multipart

The LINC transmitter is an architecture that provides linear amplification using nonlinear but power efficient amplifiers. One crucial signal processing function of LINC is the signal component separator (SCS) which forms two constant-amplitude phase-modulated signals from the source signal. This paper presents an analog SCS chip implemented in a 0.35 mum CMOS process using a novel design based on

Objective: The objective of this article was to review some methodological issues in this field and give an overview of empirical research findings with a special focus on factors associated with or affecting subjective quality of life in people with a severe mental illness. Method: A selective review of relevant scientific literature on quality of life in severe mental illness was conducted. Resu

Specialiteten njurmedicin omfattar prevention, diagnostik och behandling av parenkymatös njursjukdom. Målsättningen är att förhindra kronisk njursvikt, uremi. Men om terminal njursvikt skulle uppstå erbjuds så kallas aktiv uremivård, dvs dialys och njurtransplantation. I temat diskuteras olika aspekter av den aktiva uremivården i Sverige.

Calculating single-particle (Nilsson) levels in axially symmetric quadrupole-deformed potentials in coordinate space, the structure of weakly bound neutron orbits is studied in the absence of pair correlation. It is shown that in the wave functions of Omega(pi)=1/2(+) orbits, where Omega expresses the projection of the particle angular momentum along the symmetry axis, the l=0 (s(1/2)) component b

Since the cloning in 1990 of cDNA corresponding to mRNA transcribed at the blood group ABO locus, polymorphisms at the ABO locus and phenotype-genotype correlation have been analysed by several investigators. An enhancer-active minisatellite motif reported to contain four 43-bp repeats has been analysed by PCR in blood samples from 160 random Swedish blood donors. Different sizes of the DNA fragme

Lightweight walls are often designed as frameworks of studs with plates on each side-a double-plate structure. The studs constitute boundaries for the cavities, thereby both affecting the sound transmission directly by short-circuiting the plates, and indirectly by disturbing the sound field between the plates. The paper presents a deterministic prediction model for airborne sound insulation inclu

Mediatorless, electrochemically driven, redox transformations of TI (type 1) and T2 copper sites in Trametes hirsuta laccase were studied by cyclic voltarnmetry and spectroclectrochernical redox titrations using bare gold electrode. DET (direct electron transfer) between I he electrode and the enzyme was observed under anaerobic conditions. From analysis of experimental data it is concluded that t

Late Weichselian lake sediments from a site in southern Sweden, were analysed for stable carbon and oxygen isotopes, as well as plant macrofossils and insect remains. By comparison of independent data sets, general climatic changes were demonstrated. Lithological, chemical and stable isotope data reveal two significant climatic oscillations at ca. 12 200-12 000 and ca. 11 000-10 200 yr BP respecti

Fog droplet formation and growth related to fog droplet activation were studied in a polluted region. The joint field experiments were carried out at San Pietro Capofiume in northern Italy during November 1994. It was found that the fog droplet number distribution was continuous in the size region 1-47 µm and that for most of the time the fog consisted of unactivated droplets, i.e. the droplets we

A robust method is presented for electrocardiogram (ECG)-based estimation of the respiratory frequency during stress testing. Such ECGs contain highly nonstationary noise and exhibit changes in QRS morphology which, when combined with the dynamic nature of the respiratory frequency, make most existing methods break down. The present method exploits the oscillatory pattern of the rotation angles of

A presentation of The Nordic languages: An international handbook of the history of North Germanic languages (vol. 1 appeared in 2002, vol. 2 in 2005). Methodical and theoretical pluralism are graned to the contributors. The general organization and periodization of the work is discussed. An outline is given how the work was intended to handle synchrony vs. diachrony, language us vs. language syst

Objective: To investigate if administration of CNI-1493, an inhibitor of the synthesis of proinflammatory cytokines and NO, protects against development of joint destruction in collagen induced arthritis ( CIA) in rats. Methods: In a placebo controlled experiment, CNI-1493 was given once daily intraperitoneally after onset of clinical arthritis in DA rats. Disease progression was studied by clinic