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Overcoming extended lag phase on optically pure lactic acid production from pretreated softwood solids

Optically pure lactic acid (LA) is needed in PLA (poly-lactic acid) production to build a crystalline structure with a higher melting point of the biopolymer than that of the racemic mixture. Lignocellulosic biomass can be used as raw material for LA production, in a non-food biorefinery concept. In the present study, genetically engineered P. acidilactici ZP26 was cultivated in a simultaneous sac

A gathering with fire : Exploring the audience reception of internet memes about Belfast riots

This study sheds light upon how memes about rioting in present-day Belfast are read by their audiences. As such, it answers to a distinct research gap in the meme studies literature, which has mostly shied away from in-depth engagements with audiences, favouring instead the intertwined concepts ‘imagined audience’ and the ideological ‘directionality’ of memes. Drawing on semi-structured interviews

The use of antibiotic-loaded bone cement and systemic antibiotic prophylactic use in 2,971,357 primary total knee arthroplasties from 2010 to 2020 : an international register-based observational study among countries in Africa, Europe, North America, and Oceania

Background and purpose — Antibiotic-loaded bone cement (ALBC) and systemic antibiotic prophylaxis (SAP) have been used to reduce periprosthetic joint infection (PJI) rates. We investigated the use of ALBC and SAP in primary total knee arthroplasty (TKA). Patients and methods — This observational study is based on 2,971,357 primary TKAs reported in 2010–2020 to national/regional joint arthroplasty

Multiplicity and rapidity dependence of K ∗(892) and ϕ(1020) production in p–Pb collisions at √sNN= 5.02 TeV

The transverse-momentum (pT) spectra of K ∗(892)0 and ϕ(1020) measured with the ALICE detector up to pT = 16 GeV/c in the rapidity range - 1.2 < y< 0.3 , in p–Pb collisions at the center-of-mass energy per nucleon–nucleon collision sNN=5.02 TeV are presented as a function of charged particle multiplicity and rapidity. The measured pT distributions show a dependence on both multiplicity and rapidit

Cumulative live birth rate after IVF : Trend over time and the impact of blastocyst culture and vitrification

STUDY QUESTION: Has cumulative live birth rate (CLBR) improved over time and which factors are associated with such an improvement? SUMMARY ANSWER: During an 11-year period, 2007-2017, CLBR per oocyte aspiration increased significantly, from 27.0% to 36.3%, in parallel with an increase in blastocyst transfer and cryopreservation by vitrification. WHAT IS KNOWN ALREADY: While it has been shown that

Detection and quantification of lipid-mediated siRNA delivery to the cytosol

Cancer is one of the leading causes of death globally. Novel therapeutics is urgently needed to advance treatment, especially for generalized disease where current treatment options have a poor prognosis. In particular, targeted therapy that can address genetic changes would be of great value. RNA interference is an evolutionary conserved gene regulatory mechanism that can be used by introducing e

W-boson angular coefficients at LHC at high precision

We present state-of-the-art high-precision theory predictions for the dominant angular coefficients parametrizing the spin-correlations in the production and decay of a W-boson produced at transverse momentum larger than 30 GeV. The computation at NNLO QCD and NLO EW accuracy are combined to obtain differential distributions in the W-boson transverse momentum and rapidity. The found results show u

Search for resonant WZ production in the fully leptonic final state in proton–proton collisions at √s=13 TeV with the ATLAS detector

A search for a WZ resonance, in the fully leptonic final state (electrons or muons), is performed using 139 fb - 1 of data collected at a centre-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. The results are interpreted in terms of a singly charged Higgs boson of the Georgi–Machacek model, produced by WZ fusion, and of a Heavy Vector Triplet, with the resonance produc

Endoscopic papillectomy for ampullary lesions in patients with familial adenomatous polyposis compared with sporadic lesions: A propensity score-matched cohort

Background Familial adenomatous polyposis (FAP) is a rare inherited syndrome that predisposes the patient to cancer. Treatment of FAP-related ampullary lesions is challenging and the role of endoscopic papillectomy has not been elucidated. We retrospectively analyzed the outcomes of endoscopic papillectomy in matched cohorts of FAPrelated and sporadic ampullary lesions (SALs). Methods This retrosp

Measurement of substructure-dependent jet suppression in Pb+Pb collisions at 5.02 TeV with the ATLAS detector

The ATLAS detector at the Large Hadron Collider has been used to measure jet substructure modification and suppression in Pb+Pb collisions at a nucleon–nucleon center-of-mass energy √sNN = 5.02 TeV in comparison with proton–proton (pp) collisions at √s = 5.02 TeV. The Pb+Pb data, collected in 2018, have an integrated luminosity of 1.72 nb−1, while the ppdata, collected in 2017, have an integrated

DSAM Lifetime Studies for Gd-Nd nuclei with EUROBALL and AFRODITE

Lifetimes of high-spin states have been measured for 142Gd and 134Nd with EU-ROBALL IV and AFRODITE, respectively, using DSAM. From calculations in the cranked Nilsson-Strutinsky model it was concluded that at the high-spin states of the (+,0)1 band, 142Gd represents a triaxial nucleus rotating around the longest principal axis.

Imagination

Imagination is a human capacity that reproduces and transforms experiences and thoughts. The capacity is manifested in children's pretend play and is an important part of adults' ability to process the past, and to plan the future. A first step in the development of imagination is the ability to represent objects and events and to change these representations into alternatives to reality. For adap

A Review of Isobutanol as a Fuel for Internal Combustion Engines

Isobutanol, one of the four isomers of butanol (C4H9OH), possesses some favorable properties that make it an attractive fuel for internal combustion engines. For instance, when compared to ethanol, isobutanol features a higher heating value and lower hygroscopicity (which prevents corrosion and enables it to be transported via pipelines). Moreover, its addition to gasoline does not distort the fue

Pain as bad as you can imagine or extremely severe pain? A randomized controlled trial comparing two pain scale anchors

Background: A common method of pain assessment is the numerical rating scale, where patients are asked to rate their pain on a scale from 0 to 10, where 0 is “no pain” and 10 is “pain as bad as you can imagine”. We hypothesize such language is suboptimal as it involves a test of a cognitive skill, imagination, in the assessment of symptom severity. Methods: We used a large-scale online research re

Does Testicular Sperm Improve Intracytoplasmic Sperm Injection Outcomes for Nonazoospermic Infertile Men with Elevated Sperm DNA Fragmentation? A Systematic Review and Meta-analysis

Context: For nonazoospermic infertile men with elevated sperm DNA fragmentation (SDF), it is unclear whether the use of testicular sperm for intracytoplasmic sperm injection (ICSI) may offer advantages over ejaculated sperm. Objective: To determine whether ICSI outcomes (fertilisation rate, pregnancy rate, miscarriage rate, and live birth rate) are better with testicular sperm than with ejaculated

Success in a niche market: a grounded theory analysis of video-on-demand platforms for performing arts in Europe

Study purpose: This paper delves into the nuances of success in the niche market of video-on-demand (VoD) platforms for performing arts in Europe, focusing on managerial perspectives. It seeks to comprehend how top executives construct success and the associated meanings in their strategic decisions within this market, where success is often equated with profitability, survival, or expansion. The

Prompt Thrombo-Inflammatory Response to Ischemia-Reperfusion Injury and Kidney Transplant Outcomes

Introduction: In kidney transplantation (KT), the role of the intravascular innate immune system (IIIS) in response to ischemia-reperfusion injury (IRI) is not well-understood. Here, we studied parallel changes in the generation of key activation products of the proteolytic cascade systems of the IIIS following living donor (LD) and deceased donor (DD) transplantation and evaluated potential assoc