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Biofilms are intricate bacterial communities prevalent in diverse environments and rely on complex physiological adaptations and interactions to manifest community-intrinsic properties. The biofilm matrix itself is a major contributor to biofilm dynamics, as one of the mediators of the interactions within the biofilm, and it is composed of a diverse array of molecules. This project focuses on Sten
Recent years have seen an increase in reports on rising wildfire occurrences in countries of the Middle East. Wildfires are integral parts of terrestrial ecosystems and as such prone to the recent, large-scale anthropogenic changes of global ecosystem dynamics. However, the systematic analysis of patterns of wildfire occurrences – fire regimes – is concentrated on a few well studied regions and re
The following thesis seeks to explore the role of myth-making and securitisation in the United Kingdom’s ontological security and identity formation, as seen in their discourses surrounding security and the normalisation of far-right imaginaries and sentiments. It uses the United Kingdom as a case study in lieu of studying the larger phenomena of how national identity has been framed in security d
Behovet av förnybar energi är stort och förväntas öka i framtiden. I Sverige står vattenkraft för en betydande andel av elproduktionen, där anläggningarna ofta innebär fysiska hinder för vandringsberoende fiskarter. För att bibehålla elproduktionen och samtidigt säkerställa god konnektivitet i vattendragen krävs väl fungerande migrationslösningar förbi kraftverken, både för uppströmsvandrande och The need for renewable energy is substantial and is expected to increase in the future. In Sweden, hydropower accounts for a significant portion of the energy production, with facilities often presenting physical barriers to migratory fish species. To maintain electricity production while ensuring good connectivity in watercourses, effective migration solutions past the power plants are required f
In recent years, the Multi-Pass Cell (MPC) has been increasingly employed and researched upon, after emerging as a promising post-compression technique for making ultrafast laser pulses shorter. Like most post-compression techniques, MPCs utilize a nonlinear effect, Self-Phase Modulation (SPM), which stems from the intensity-dependence of the refractive index of certain nonlinear materials, to ove
MORC2 (Microorchidia CW type Zinc Finger protein 2) is a GHKL (gyrase, heat shock protein 90, histidine kinase, MutL) ATPase involved in chromatin remodeling and is highly conserved in eukaryotes. Mutations in the ATPase domain of MORC2 are known to cause neurodevelopmental disorders. MORC2 is recruited by the HUSH complex to target long, intronless transcription units such as LINE-1 retrotranspos
Today, breast cancer is the most common malignant disease among females worldwide. To predict the prognosis for outcome of the breast cancer, a number of prognostic factors are used such as the axillary lymph node status which is one of several factors to be evaluated when staging the disease. The axilla is routinely staged during sentinel lymph node biopsy excising a couple of lymph nodes to eval
Bacterial cellulose (BC) is a versatile and biocompatible polysaccharide produced by bacteria, with Komagataeibacter xylinus being the model species for its production. This polymer has unique properties that make it valuable in several applications, including as a rheology modifier in cosmetics. Cellugy, a Danish start-up, produces EcoFLEXY, a BC-based rheology modifier that enhances the viscosit
Neurodegenerative diseases are becoming an increasing social and economic burden worldwide. A subset of neurodegenerative diseases, called tauopathies, accumulate abnormally aggregated tau (a microtubule-binding protein) as one of their main pathological hallmarks. The role of microglia, the immune cells of the central nervous system, in tau pathology, has been increasingly discussed in the past y
LINE1s are a subfamily of retrotransposons occupying around 17-21% of our genome. Most of these have lost their ability to transpose on their own, due to truncation of 5’UTR or the accumulation of mutations. Despite this, they can act as cis-regulatory elements and affect gene expression. One RNA modification has been proposed to regulate their expression is called N6-methyladenosine (m6A). It is
The Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands
Stroke is a highly debilitating disease of the central nervous system occurring as a result of cerebral ischemia – deprivation of a cerebral tissue from blood that supplies it with oxygen and glucose, causing the cells in affected tissue to die, bringing about a large number of downstream effects and responses. Localized infarction in the brain also triggers tissue death and related responses in r
Asymmetric catalysis plays a crucial role in chemistry. It enables the efficient and selective production of chiral molecules, essential in e.g. the pharmaceutical industry. This research explores the development of a dibenzo[a,e]cyclooctatetraene ligand. This ligand has previously shown great potential in asymmetric synthesis where the corresponding rhodium(I)-complex gives excellent enantiosele
Urbanization has led to significant infrastructural challenges, particularly in the slum areas of the Global South. Nature-based Solutions (NbS) are emerging as innovative approaches to enhance urban sustainability and resilience. This study investigates the enabling environment for decentralized governance in implementing NbS within urban slums, focusing on case studies in Indonesia and the Phili
Desertification has become an increasing concern in the Sahelian landscape. Initiatives, such as the Great Green Wall (GGW) and Action Against Desertification (AAD) are aimed at reversing the effects of desertification. Using the AAD geographical regions as a reference, the rate of greening was analysed using high resolution Sentinel-2 satellite image data (10m) and compared to Moderate Resolution
