Sedan urminnes tider har frågor om etik och moral haft stor inverkan på människors liv. I den globaliserade och digitala värld vi idag lever i är dessa fortfarande aktuella, men har kommit att förändras. Då vi har gått från att befinna oss i en kollektiv till en konnektiv kontext, och vår kommunikation inte längre enbart sker ansikte mot ansikte, har nya etiska och moraliska frågor uppkommit. Den

Type Ia Supernovae (SNe Ia) are considered the most reliable standard candles and they have played an invaluable role in cosmology since the discovery of the Universe's accelerated expansion. During the last decades, the SNe Ia samples have been improved in number, redshift coverage, calibration methodology, and systematics treatment. These efforts led to the most recent “Pantheon” (2018) and “Pan

Older adults are frequently exposed to medicines with systemic anticholinergic properties, which are linked to increased risk of negative health outcomes. The association between systemic anticholinergics and lung function has not been reported. The aim of this study was to investigate if exposure to systemic anticholinergics influences lung function in older adults. Participants of the southernmo

The escalating demand for electricity requires the deployment of reliable, secure, and efficient energy production methods. This master thesis explores the utilization of Supervisory Control and Data Acquisition (SCADA) systems in power plants to meet these requirements. The primary objective is to investigate the specific requirements for implementing a SCADA system in the power production sector

The Concordance Index (C-index) is a commonly used metric in Survival Analysis for evaluating the performance of a prediction model. In this paper, we propose a decomposition of the C-index into a weighted harmonic mean of two quantities: one for ranking observed events versus other observed events, and the other for ranking observed events versus censored cases. This decomposition enables a finer

BACKGROUND: Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) share many pathophysiological factors including genetics, but whether epigenetic marks are shared is unknown. We aimed to test whether a DNA methylation risk score (MRS) for T2DM was associated with GDM across ancestry and GDM criteria.METHODS: In two independent pregnancy cohorts, EPIPREG (n = 480) and EPIDG (n =

Human genetic variation in PPARGC1B has been associated with adiposity, but the genetic variants that affect PPARGC1B expression have not been experimentally determined. Here, guided by previous observational data, we used CRISPR/Cas9 to scarlessly edit the alleles of the candidate causal genetic variant rs10071329 in a human brown adipocyte cell line (hBAs). Switching the rs10071329 genotype from

a-particle emitters are emerging as a potent modality for disseminated cancer therapy because of their high linear energy transfer and localized absorbed dose profile. Despite great interest and pharmaceutical development, there is scant information on the distribution of these agents at the scale of the a-particle pathlength. We sought to determine the distribution of clinically approved [223Ra]R

Background: Musculoskeletal disorders (MSK) are a global burden causing significant suffering and economic impact. Systematic identification and targeting of research questions of highest interest for stakeholders can aid in improving MSK disorder knowledge and management. Objective: To obtain Swedish MSK researchers' opinions and views on a collaborative Swedish MSK network (SweMSK) and identify

Allowing for free choice of the recipient's gender in a dictator game (N=357), women give more frequently to their own gender (70.3% vs 9.4%) while men do not prefer a specific recipient's gender (33.3% vs 27.8%). Conditional on a positive transfer being made, the average amount of transfers to each gender does not vary between genders, though. Once a charity recipient is added to the possible cho

Let G be a Lie group equipped with a left-invariant semi-Riemannian metric. Let K be a semisimple subgroup of G generating a left-invariant conformal foliation F of codimension two on G. We then show that the foliation F is minimal. This means that locally the leaves of F are fibres of a complex-valued harmonic morphism. In the Riemannian case, we prove that if the metric restricted to K is biinva

Vision is an important sensory modality in birds, which can outperform other vertebrates in some visual abilities. However, sensitivity to achromatic contrasts - the ability to discern luminance difference between two objects or an object and its background - has been shown to be lower in birds compared with other vertebrates. We conducted a comparative study to evaluate the achromatic contrast se

In this paper, we considered the real-time modeling of an underwater channel impulse response (CIR), exploiting the inherent structure and sparsity of such channels. Building on the recent development in the modeling of acoustic channels using a Kronecker structure, we approximated the CIR using a structured and sparse model, allowing for a computationally efficient sparse block-updating algorithm

mmWave communication has come up as the unexplored spectrum for 5G services. With new standards for 5G NR positioning, more off-the-shelf platforms and algorithms are needed to perform indoor positioning. An object can be accurately positioned in a room either by using an angle and a delay estimate or two angle estimates or three delay estimates. We propose an algorithm to jointly estimate the ang

The intricate interplay between colloidal particle shape and precisely engineered interaction potentials has paved the way for the discovery of unprecedented crystal structures in both two and three dimensions. Here, we make use of anisotropic triblock colloidal particles composed of two distinct materials. The resulting surface charge heterogeneity can be exploited to generate regioselective depl

In situ interfacial rheology and numerical simulations are used to investigate microgel monolayers in a wide range of packing fractions, ζ2D. The heterogeneous particle compressibility determines two flow regimes characterized by distinct master curves. To mimic the microgel architecture and reproduce experiments, an interaction potential combining a soft shoulder with the Hertzian model is introd

It is commonly believed that the most efficient way to pack a finite number of equal-sized spheres is by arranging them tightly in a cluster. However, mathematicians have conjectured that a linear arrangement may actually result in the densest packing. Here, our combined experimental and simulation study provides a physical realization of the finite sphere packing problem by studying arrangements