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Being a non-native English speaker in science and medicine

The use of English language as the official language in science had an undoubtable role in moving science forward but posed an extra challenge for people whose first language is not English. In this Viewpoint, six non-Native English speakers share their experience as academics, clinicians, researchers and editors who carry out the core tasks of their jobs in a second language, and suggest potentia

Terahertz permittivity parameters of monoclinic single crystal lutetium oxyorthosilicate

The anisotropic permittivity parameters of monoclinic single crystal lutetium oxyorthosilicate, Lu2SiO5 (LSO), have been determined in the terahertz spectral range. Using terahertz generalized spectroscopic ellipsometry (THz-GSE), we obtained the THz permittivities along the a, b, and c ⋆ crystal directions, which correspond to the ϵ a , ϵ b , and ϵ c ⋆ on-diagonal tensor elements. The associated

Diagnostic Accuracy of the Swedish Version of the Multicultural Cognitive Examination for Cognitive Assessment in Swedish Memory Clinics

Background: Cognitive assessment for foreign-born individuals is suboptimal. The Multicultural Cognitive Examination (MCE) was developed for use in culturally, linguistically and educationally diverse populations. The MCE includes the Rowland Universal Dementia Assessment Scale (RUDAS) and performs assessment of memory, verbal fluency, and visuospatial function. Objective: To compare the psychomet

Condition-transfer maternal effects modulate inter-locus sexual conflict

Strong sexual selection frequently favors males that increase their reproductive success by harming females, with potentially negative consequences for natural populations. Understanding what factors modulate conflict between the sexes is hence critical to understand both the evolution of male and female phenotypes and the viability of populations in the wild. Here, we model the evolution of male

The active phase of Pt(110) during catalytic CO oxidation

En förbränningsmotor, som den i din bil, har inte tillräckligt med syre för att fullständigt förbränna bränslet till koldioxid och vatten. Därigenom frigörs kolväten, kolmonoxid och kväveoxid. 98% av dessa giftiga biprodukter kan omvandlas till mindre skadliga ämnen med hjälp av en katalysator. En katalysator använder grundläggande oxidation och reduktion för att omvandla de giftiga utsläppen fråCO oxidation is an important topic in heterogeneous catalysis, due to its role in industrial processes such as pollution reduction in the auto industry, and ethanol or other fuel production. In the automotive catalytic converters CO oxidation reduces the poisonous CO to CO2 by reacting with O2. Oxidation catalysts such as Pt, Pd and Rh are frequently used as catalytic converters for CO oxidation i

In-situ study of the impact of temperature and architecture on the interfacial structure of microgels

The structural characterization of microgels at interfaces is fundamental to understand both their 2D phase behavior and their role as stabilizers that enable emulsions to be broken on demand. However, this characterization is usually limited by available experimental techniques, which do not allow a direct investigation at interfaces. To overcome this difficulty, here we employ neutron reflectome

Two-step deswelling in the Volume Phase Transition of thermoresponsive microgels

Thermoresponsive microgels are one of the most investigated types of soft colloids, thanks to their ability to undergo a Volume Phase Transition (VPT) close to ambient temperature. However, this fundamental phenomenon still lacks a detailed microscopic understanding, particularly regarding the presence and the role of charges in the deswelling process. This is particularly important for the widely

Charge affinity and solvent effects in numerical simulations of ionic microgels

Ionic microgel particles are intriguing systems in which the properties of thermo-responsive polymeric colloids are enriched by the presence of charged groups. In order to rationalize their properties and predict the behaviour of microgel suspensions, it is necessary to develop a coarse-graining strategy that starts from the accurate modelling of single particles. Here, we provide a numerical adva

Microgels at Interfaces Behave as 2D Elastic Particles Featuring Reentrant Dynamics

Soft colloids are increasingly used as model systems to address fundamental issues such as crystallization and the glass and jamming transitions. Among the available classes of soft colloids, microgels are emerging as the gold standard. Since their great internal complexity makes their theoretical characterization very hard, microgels are commonly modeled, at least in the small-deformation regime,

Tuning the rheological behavior of colloidal gels through competing interactions

We study colloidal gels formed by competing electrostatic repulsion and short-range attraction by means of extensive numerical simulations under external shear. We show that, upon varying the repulsion strength, the gel structure and its viscoelastic properties can be largely tuned. In particular, the gel fractal dimension can be either increased or decreased with respect to mechanical equilibrium

Optimization of pore geometry, pore density and membrane material for nanoelectroporation

Injektion av specifikt utvalt DNA i celler är en teknik som har många användningsområden, tillexempel i cell- och genterapier men också för att studera orsaker till olika sjukdomar som diabetes. Målet med att introducera DNA är att få cellen att bete sig på ett önskat sätt. Anledningen till detta kan vara för att antingen kunna använda cellen som en behandling mot cancer, eller för att åstadkomma Electroporation is a technique used to transfect cells, i.e. to introduce nucleic acids in cells. The method consists in applying a voltage over the cells which leads to the opening of pores in the cell membrane through which cargo can diffuse to the cell interior. If the cells are cultivated on top of nanopores or nanostraws, dielectric structures one can achieve nanoelectroporation when applying

GPU acceleration of splitting schemes applied to differential matrix equations

We consider differential Lyapunov and Riccati equations, and generalized versions thereof. Such equations arise in many different areas and are especially important within the field of optimal control. In order to approximate their solution, one may use several different kinds of numerical methods. Of these, splitting schemes are often a very competitive choice. In this article, we investigate the

Nackas framtid - En riskanalys för gentrifiering i samband med tunnelbanetillgänglighet

The municipality of Nacka is undergoing major urban development and transformation which is part of the project [Nacka becomes a city] which includes new developments of housing, commercial property, and shopping areas aimed to make Nacka a city. The project is driven by the expansion of the Stockholm metro system which is getting extended to Nacka. Such major changes of an urban area in correlati

Samtal och Samråd: En studie av kommunikation i samrådsprocessen i en detaljplan

The consultation process in Swedish planning provides an opportunity for citizens to participate in the planning process. Yet the influence of the citizens is varied and their ability to interact with the planners and the developer can sometimes be problematic. Using Haberma’s theory of communicative action, this study analyzes the interactions between the planners, contractors and citizens in the

Epidermal ET-1 signal induces activation of resting hair follicles by upregulating the PI3K/AKT pathway in the dermis

The prevalence of alopecia has increased recently. Hair loss is often accompanied by the resting phase of hair follicles (HFs). Dermal papilla (DP) plays a crucial role in HF development, growth, and regeneration. Activating DP can revive resting HFs. Augmenting WNT/β-catenin signaling stimulates HF growth. However, the factors responsible for activating resting HFs effectively are unclear. In thi

Mass spectroscopy reveals compositional differences in copepodamides from limnic and marine copepods

Marine copepods, the most abundant animals in the global ocean, imprint their surrounding waters with chemical cues, called copepodamides. Copepodamides induce defensive traits such as toxin production, bioluminescence, and colony size plasticity in a variety of marine phytoplankton. The role of copepodamides in freshwater ecosystems is, however, unknown. Here we report the consistent presence of

Effects of certain pre-analytical factors on the performance of plasma phospho-tau217

Introduction: Pre-analytical factors can cause substantial variability in the measurements of cerebrospinal fluid (CSF) and plasma biomarkers of Alzheimer’s disease (AD). However, their effects on the performance of one of the most promising plasma AD biomarkers, phosphorylated tau (p-tau)217, are not known. Methods: We included 50 amyloid-β positive (Aβ+) and 50 Aβ− participants from the Swedish

The galactic acceleration scale is imprinted on globular cluster systems of early-type galaxies of most masses and on red and blue globular cluster subpopulations

Context. Globular clusters (GCs) carry information about the formation histories and gravitational fields of their host galaxies. It was found before that the radial profiles of the volume number density of GCs in GC systems (GCSs) follow broken power laws, while the breaks occur approximately at the a0 radii. These are the radii at which the gravitational fields of the galaxies equal the galactic

Patient-reported outcomes in axial spondyloarthritis and psoriatic arthritis patients treated with secukinumab for 24 months in daily clinical practice

Objectives: In patients with axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA) initiating secukinumab, we aimed to assess and compare the proportion of patients achieving 6-, 12- and 24-month patient-reported outcomes (PRO) remission and the 24-month retention rates. Patients and methods: Patients with axSpA or PsA from 16 European registries, who initiated secukinumab in routine care w