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Trinorsesquiterpenoids from the Root Extract of Pentalinon andrieuxii

Two unusual trinorsesquiterpenoids, urechitols A (1) and B (2), were isolated from the root extract of Pentalinon andrieuxii, a plant used commonly in Yucatecan traditional medicine to treat leishmaniasis. The structures of I and 2 were identified by interpretation of their spectroscopic data and chemical correlation reactions. The relative stereochemistry of I was confirmed through an X-ray cryst

Analysis of a high frequency and wide bandwidth active polyphase filter based on CMOS inverters

An active polyphase filter capable of high frequency quadrature signal generation has been analyzed. The resistors of the classical passive polyphase filter have been replaced by transconductors, CMOS inverters [1,2]. A three-stage 0.13 um CMOS active polyphase filter has been designed. Simulations with a differential input signal show a quadrature error less than 1◦ for the full stable input volt

On Falls in the Elderly –Epidemiological Studies from the Longitudinal General Population Study ‘Good Aging in Skåne’ (GÅS), Sweden

Popular Abstract in Swedish Fallolyckor hos äldre -en tyst epidemi Fallolyckor hos äldre är idag ett omfattande men underrapporterat hälsoproblem. Cirka 1,600 individer, en huvuddel äldre, avlider årligen i Sverige till följd av ett fall. Detta kan jämföras med 1,400 respektive 2,400 individer som avlider årligen av bröst- och prostatacancer. Strax under 300 individer dör årligen i trafiken i SveIn a ‘greying world’ with aging populations, falls in the elderly are a challenge to the health care system as they are associated with substantial mortality and morbidity. Apart from physical injuries, the consequences of falls are broad, with additional psychological and social consequences. The overall objective of this dissertation was to study falls and related risk factors, predictors, and c

Recovery in personal care related to cognitive impairment before and after stroke - a 1-year follow-up

Objective - To examine whether there were any differences in the recovery in performance of personal activities of daily living (P-ADL) in elderly persons in relation to cognitive impairments pre- and post-stroke from discharge to 6 and 12 months in elderly persons. Methods - Forty-five elderly persons after stroke were assessed at discharge from hospital and at 6 and at 12 months after stroke ons

Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study

To identify markers of non-response to neoadjuvant chemotherapy (NAC) that could be used in the adjuvant setting. Sixteen pathologists of the European Working Group for Breast Screening Pathology reviewed the core biopsies of breast cancers treated with NAC and recorded the clinico-pathological findings (histological type and grade; estrogen, progesterone receptors, and HER2 status; Ki67; mitotic

Experimental verification of reciprocity relations in quantum thermoelectric transport

Fundamental symmetries in thermoelectric quantum transport, beyond Onsagers relations, were predicted two decades ago but have to date not been observed in experiments. Recent works have predicted the symmetries to be sensitive to energy-dependent, inelastic scattering, raising the question whether they exist in practice. Here, we answer this question affirmatively by experimentally verifying the

Reglering av värmesystem i flerbostadshus med individuell värmemätning

Indoor temperatures in multifamily houses are indirectly controlled by the outdoor temperature. The radiator supply temperature is a function of the outdoor temperature. This control principle cannot take into account for disturbances from people, electric appliances, airing, sun, and air leakage due to wind. A control setting with a suitable margin can avoid complaints, but may result in overheat

Detection and localization of load coils from one-port measurements

Abstract in UndeterminedThis paper deals with detection and localization of load coils in the copper access network. The load coil is a legacy device that must be removed before deploying broadband services on twisted-pair transmission lines. The proposed methods do not require dedicated hardware but utilize the already installed transceivers for one-port measurements of the line input impedance.

Observer forms for perspective systems

The estimation of three-dimensional position information from two-dimensional images in computer vision systems can be formulated as a state estimation problem for a nonlinear perspective dynamic system. The multi-output state estimation problem has been treated by several authors using methods for nonlinear observer design. This paper shows that a perspective system can be transformed to two obse

Regulation of callose synthase activity in situ in alamethicin-permeabilized Arabidopsis and tobacco suspension cells

Background: The cell wall component callose is mainly synthesized at certain developmental stages and after wounding or pathogen attack. Callose synthases are membrane-bound enzymes that have been relatively well characterized in vitro using isolated membrane fractions or purified enzyme. However, little is known about their functional properties in situ, under conditions when the cell wall is int

Exploring the Ambiguity of Hybrid Organisations: A Stakeholder Approach.

This paper focuses on hybrid organisations, which have both public and private sector elements. Therefore, stakeholders of hybrid organisations have different views regarding what to expect from the organisation and the role of stakeholders tend to be multifaceted. This creates ambiguity that imposes demands on the management of hybrid organisations. In this paper a stakeholder approach is used in

Searching for Celiac Disease Screening-detected celiac disease in an HLA-genotyped birth cohort

Popular Abstract in Swedish Celiaki, även kallat glutenintolerans, är en tarminflammation orsakad av vissa sädesslag i kosten och förekommer hos både barn och vuxna. Sjukdomen drabbar ca 1% av befolkningen i västvärlden och betraktas som en av de vanligaste kroniska sjukdomarna bland svenska barn. Många individer med sjukdomen är oupptäckta och kan bara hittas via s.k. screening, d.v.s. att man leObjectives: Celiac disease is a common immune mediated enteropathy strongly associated with HLA-DQB1*02 (DQ2), *0302 (DQ8), or both and the presence of tissue transglutaminase autoantibodies (tTGA). Prevalence studies have revealed that most affected individuals go undetected because of subclinical signs or being asymptomatic rendering screening a method for identification. However, less is known

A thermostable phytase from Bacillus sp. MD2: cloning, expression and high-level production in Escherichia coli.

Phytase is used as a feed additive for degradation of antinutritional phytate, and the enzyme is desired to be highly thermostable for it to withstand feed formulation conditions. A Bacillus sp. MD2 showing phytase activity was isolated, and the phytase encoding gene was cloned and expressed in Escherichia coli. The recombinant phytase exhibited high stability at temperatures up to 100 degrees C.

Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer

Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation carriers, accumulation of stem and progenitor cells in normal breast tissue and increased risk of developing tumors of basal-like type suggest that BRCA1 regulates stem/progenitor cell proliferation and differentiation. However, the function