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Mapping the architecture of the temporal artery with photoacoustic imaging for diagnosing giant cell arteritis

Photoacoustic (PA) imaging is rapidly emerging as a promising clinical diagnostic tool. One of the main applications of PA imaging is to image vascular networks in humans. This relies on the signal obtained from oxygenated and deoxygenated hemoglobin, which limits imaging of the vessel wall itself. Giant cell arteritis (GCA) is a treatable, but potentially sight- and life-threatening disease, in w

The present is a knife’s edge : St. Augustine’s philosophical presentism and the politics of expectation

The ways in which expectations for the future shape how actors and organizations make sense of the present has received growing interest and attention among science and technology scholars – with particular attention being paid to the role of expectations and prediction making in technology and finance. Nevertheless, while the imaginaries involved in the futures described by tech-entrepreneurs and

Sequence of flexion contracture development in the lower limb : a longitudinal analysis of 1,071 children with cerebral palsy

Background: To prevent severe contractures and their impact on adjacent joints in children with cerebral palsy (CP), it is crucial to treat the reduced range of motion early and to understand the order by which contractures appear. The aim of this study was to determine how a hip–knee or ankle contracture are associated with the time to and sequence of contracture development in adjacent joints. M

Heart age estimated using explainable advanced electrocardiography

Electrocardiographic (ECG) Heart Age conveying cardiovascular risk has been estimated by both Bayesian and artificial intelligence approaches. We hypothesised that explainable measures from the 10-s 12-lead ECG could successfully predict Bayesian 5-min ECG Heart Age. Advanced analysis was performed on ECGs from healthy subjects and patients with cardiovascular risk or proven heart disease. Regress

Shorter reproductive life span is associated with increased cardiovascular risk and total mortality in Swedish women from an observational, population-based study

Objectives: Reproductive history of women is of importance to estimate cardiovascular disease (CVD) risk. One aspect of that history is the reproductive life span (RLS), the period between onset of menarche and menopause. Previous studies have indicated an increased risk associated with shorter RLS, but this has never previously been tested in Scandinavian women. Our aim was to investigate such as

Laser excitation effects in lifetime-based high-speed phosphor thermometry

With high-speed phosphor thermometry becoming more established follows the need for an improved understanding of laser excitation induced measurement errors. With this aim in mind, the impact of kHz laser excitation on the lifetime method was investigated for the phosphors Mg3FGeO6:Mn (MFG) and YVO4:Tm. The results showed that significant measurement errors can occur for both phosphors. The Maximu

Seismic reflectivity, fracturing and stress field data from the FFC-1 exploratory geothermal project in SW Skåne, Sweden

Enhanced geothermal systems (EGS) are a potential heat source in many parts of the world, even in locations where the temperature gradient is relatively low. We present here an integrated study of reflection seismic data, borehole logs and seismicity analysis performed in conjunction with a geothermal exploratory project operated by E.ON in Malmö, Sweden. In 2020, the pre-existing 2.1 km deep FFC-

A moving-boundary model of reactive settling in wastewater treatment. Part 2 : Numerical scheme

A numerical scheme is proposed for the simulation of reactive settling in sequencing batch reactors (SBRs) in wastewater treatment plants. Reactive settling is the process of sedimentation of flocculated particles (biomass; activated sludge) consisting of several material components that react with substrates dissolved in the fluid. An SBR is operated in cycles of consecutive fill, react, settle,

Child labour and health hazards: chemical exposure and occupational injuries in Nicaraguan children working in a waste disposal site

Omkring 600 barn och tonåringar arbetar på Managuas stora soptipp, denbstörsta i Nicaragua. De samlar och sorterar avfall på den öppna tippen, sombtäcker ett 7 km2 stort område i stadens utkant vid stranden av Managuasjön. Sådant arbete, som förekommer i många stora städer i utvecklingsländer, ansesbvara ett av de mest riskfyllda typerna av barnarbete som finns. Ändå är kunskapen om sådant arbete About 600 children and teenagers work at Managua's landfill, the largest in Nicaragua. They collect and sort waste at the open dump, which covers an area of 7 km2 on the outskirts of the city on the shores of Lake Managua. Such work, which occurs in many large cities in developing countries, is considered to be one of the riskiest types of child labor that exists. Nevertheless, knowledge of such w

Thrombotic risk determined by rare and common SERPINA1 variants in a population-based cohort study

Background: Severe alpha-1-antitrypsin deficiency (AATD), phenotype PiZZ, was associated with venous thromboembolism (VTE) in a case-control study. Objectives: This study aimed to determine the genetic variation in the SERPINA1 gene and a possible thrombotic risk of these variants in a population-based cohort study. Patients/Methods: The coding sequence of SERPINA1 was analyzed for the Z (rs289294

The shortest even cycle problem is tractable

Given a directed graph as input, we show how to efficiently find a shortest (directed, simple) cycle on an even number of vertices. As far as we know, no polynomial-time algorithm was previously known for this problem. In fact, finding any even cycle in a directed graph in polynomial time was open for more than two decades until Robertson, Seymour, and Thomas (Ann. of Math. (2) 1999) and, independ

A dissimilar non-matching HDG discretization for Stokes flows

In this work we propose and analyze an HDG method for the Stokes equation whose domain is discretized by two independent polygonal subdomains with different meshsizes. This causes a non-conformity at the intersection of the subdomains or leaves a gap (unmeshed region) between them. In order to appropriately couple these two different discretizations, we propose suitable transmission conditions to

Reductions in greenhouse gas emissions through innovative co-production of bio-oil in combined heat and power plants

Integrating fast pyrolysis into existing biomass-based combined heat and power (CHP) plants offers an innovative opportunity for plant operators to acquire an additional heat sink and produce a renewable transport fuels feedstock. This technology is particularly interesting in Sweden, where biobased heat and power constitute an important part of the energy system. It is important to establish the

Computing Nodal Deficiency with a Refined Dirichlet-to-Neumann Map

Recent work of the authors and their collaborators has uncovered fundamental connections between the Dirichlet-to-Neumann map, the spectral flow of a certain family of self-adjoint operators, and the nodal deficiency of a Laplacian eigenfunction (or an analogous deficiency associated to a non-bipartite equipartition). Using a refined construction of the Dirichlet-to-Neumann map, we strengthen all

Signal-enhanced Raman spectroscopy with a multi-pass cavity for quantitative measurements of formaldehyde, major species and temperature in a one-dimensional laminar DME-air flame

While Raman spectroscopy provides opportunities for simultaneous detection and quantitative analysis of multiple species, it also suffers from certain limitations, such as low signal strength, which often makes it unsuitable for the study of minor species. The present work employs a high-repetition-rate and high-power laser and re-introduces an amplification technique to improve the detection limi

Influence of interface states on built-in electric field and diamagnetic-Landau energy shifts in asymmetric modulation-doped InGaAs/GaAs QWs

The impact of interface defect states on the recombination and transport properties of charges in asymmetric modulation-doped InGaAs/GaAs quantum wells(QWs) is investigated. Three sets of high-mobility InGaAs QW structures are systematically designed and grown by the metal-organic vapor phase epitaxy technique to probe the effect of carrier localization on the electro-optical processes. In these s

Simple and farmer-friendly bumblebee conservation : Straw bales as nest sites in agricultural landscapes

Many bumblebee species are declining due to a loss of semi-natural habitats in agricultural landscapes resulting in diminished forage and nest sites. Anecdotal experience indicates that bumblebees nest in straw bales, but scientific evidence is lacking. We spent 250 h screening for bumblebee nests in 1255 straw bales and ten straw stacks belonging to 58 farms in two intensively farmed Swedish regi

FDA-MIMO radar detection for independent and nonidentically distributed fluctuating targets

Due to its range-dependent target response, frequency diverse array multiple-input multiple-output (FDA-MIMO) radar systems enable superior detection capabilities as compared with conventional phased-array radars. This paper proposes an incoherent detector for airborne FDA-MIMO radar to detect independent but possibly non-identically distributed fluctuating targets. For FDA-MIMO, variations in the