In this study, we investigated the ability of Ru(ii) polypyridyl complexes to act as DNA binders. The substitution reactions of three Ru(ii) chlorophenyl terpyridine complexes, i.e. [Ru(Cl-Ph-tpy)(en)Cl]Cl (1), [Ru(Cl-Ph-tpy)(dach)Cl]Cl (2) and [Ru(Cl-Ph-tpy)(bpy)Cl]Cl (3) (Cl-Ph-tpy = 4′-(4-chlorophenyl)-2,2′:6′,2′′-terpyridine, en = 1,2-diaminoethane, dach = 1,2-diaminocyclohexane, bpy = 2,2′-bi

We describe a new technique for automatic identification of stationary, linear systems with a single output. This class of models includes all linear, time-invariant, stochastic, difference equations driven by arbitrary inputs and having stationary, normal disturbances with rational spectra.The parameters of the model are estimated by the method of maximum likelihood. A numerical algorithm for sol

We have formulated and investigated innovative lipid-based nanoparticles characterized by a reverse hexagonal liquid crystalline inner structure (hexosomes). These nanoparticles were doped with a potent, highly water insoluble anticancer drug, namely docetaxel, and stabilized by a mixture of commercial and folate- and rhodamine-conjugated Pluronic F108. Thus, they simultaneously possess therapeuti

We demonstrate how the problem of finding the effective property of quasiperiodic constitutive relations can be simplified to the periodic homogenization setting by transforming the original quasiperiodic material structure to a periodic heterogeneous material in a higher dimensional space. The characterization of two-scale cut-and-projection convergence limits of partial differential operators is

Background: Sodium fluoride (NaF) positron emission tomography combined with computer tomography (PET/CT) has shown to be more sensitive than the whole-body bone scan in the detection of skeletal uptake due to metastases in prostate cancer. We aimed to calculate a 3D index for NaF PET/CT and investigate its correlation to the bone scan index (BSI) and overall survival (OS) in a group of patients w

Maximizing the area under biodiversity-related conservation measures is a main target of the European Union (EU) Biodiversity Strategy to 2020. We analyzed whether agrienvironmental schemes (AES) within EU common agricultural policy, special protected areas for birds (SPAs), and Annex I designation within EU Birds Directive had an effect on bird population changes using monitoring data from 39 far

BACKGROUND: Patients with back and neck pain are often seen in primary care and it is important to provide them with tailored interventions based on risk stratification/triage. The STarT Back Screening Tool (SBT) is a widely used screening questionnaire which has not yet been validated for a population with back and/or neck pain with short duration. Our aim was to compare the concurrent validity o

This paper presents preliminary results for a novel 128-antenna massive Multiple-Input, Multiple-Output (MIMO) testbed developed through Bristol Is Open in collaboration with National Instruments and Lund University. We believe that the results presented here validate the adoption of massive MIMO as a key enabling technology for 5G and pave the way for further pragmatic research by the massive MIM

Den 3:e november 2016 presenterade 3:12-utredningen sitt förslag om skärpta regler kring beskattningen av fåmansbolag. 3:12-regelverket har varit omdiskuterat och förändrats ett antal gånger sedan det infördes i samband med skattereformen 1990/91 och detta förslag är sannolikt inte det sista regelförändringsförlaget. Det kan därför finnas anledning att mer principiellt diskutera hur entreprenörska

In this paper we address a sensitivity problem with financial applications. Namely the study of price variations of different contingent claims in the Black-Scholes model due to changes in volatility. This study needs an extension of the classical Vega index, i.e. the price derivative with respect to the constant volatility, which we call the local Vega index (lvi). This index measures the importa

Incisional hernia is one of the most common complications (5–20%) after abdominal surgery. Surgery is the only option to cure a hernia. Symptoms of an incisional hernia depend on the size of the abdominal wall defect and the protruding tissue. About 30% of the patients with an incisional hernia will have an operation performed. Traditional surgical sutured techniques have very high recurrence rateIncisional hernia is one of the most common complications (5–20%) after abdominal surgery. Surgery is the only option to cure a hernia. Symptoms of an incisional hernia depend on the size of the abdominal wall defect and the protruding tissue. About 30% of the patients with an incisional hernia will have an operation performed. Traditional surgical sutured techniques have very high recurrence rate

The main challenge for future electricity systems is to match the available electricity from variable renewable resources with the electricity demand in place, time and quantity. One option for increasing electricity system flexibility is to integrate the electricity system with the district heating systems via the use of power-to-heat technologies such as electric boilers. The overarching objecti

Quantification and mapping possibilities of lithium in geological material, by Nuclear Reaction Analysis (NRA), was evaluated at the Lund Ion Beam Analysis Facility (LIBAF). LiF and two Standard Reference Materials, (SRM 610 and SRM 612) were used in the investigation. The main part of the data was obtained at the beam energy 635keV studying the high Q-value reaction 7Li(p, α)4He, but reaction yie

We introduce an axiomatization for the coalgebraic fixed point logic which was introduced by Venema as a generalization, based on Moss' coalgebraic modality, of the well-known modal mucalculus. Our axiomatization can be seen as a generalization of Kozen's proof system for the modal mu-calculus to the coalgebraic level of generality. It consists of a complete axiomatization for Moss' modality, exte

Identification and quantitative monitoring of mutant BCR-ABL1 subclones displaying resistance to tyrosine kinase inhibitors (TKIs) have become important tasks in patients with Ph-positive leukemias. Different technologies have been established for patient screening. Various next-generation sequencing (NGS) platforms facilitating sensitive detection and quantitative monitoring of mutations in the A