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The repressor activator protein 1 (RAP1) plays a role in telomere structure and function inS. cerevisiae. Here, the RAP1 homologue was identified and cloned from the budding yeast Saccharomyces castellii (scasRAP1). The scasRAP1 gene encodes a protein of 826 amino acids and shares an overall high degree of similarity with the S. cerevisiae RAP1 (scerRAP1). We demonstrate that the scasRAP1 is able
Tandemly repeated 340 bp sequences, TA repeats, are present in seven of the eight pairs of chromosome ends in Chironomus pallidivittatus, being absent from the telocentric left end of chromosome four. We have previously shown that the family of TA repeats consists of four main subfamilies. One subfamily is composed of a master unit and the other three contain derived units, each of which has a sma
High plasma levels of VLDL are associated with increased risk for atherosclerosis. Here we show that VLDL (75 to 150 microg/mL) activates nuclear factor-kappaB (NF-kappaB), a transcription factor known to play a key role in regulation of inflammation. Oxidation of VLDL reduced its capacity to activate NF-kappaB in vitro, whereas free fatty acids such as linoleic and oleic acid activated NF-kappaB
Inhalation of airborne microorganisms and their toxic components and products may induce a wide spectrum of acute and chronic airway manifestations. The study describes important capabilities of chemical marker analysis in defining human exposure to microorganisms in indoor environments. An integrated procedure is presented where gas chromatography - ion trap tandem mass spectrometry is used to de
This paper gives an overview of the cadmium (Cd) situation in agricultural systems and human exposure in Sweden. Cadmium levels in agricultural soils (the plow layer) increase by 0.03% to 0.05% per year. Feed can give substantial contributions of Cd to local agricultural systems. Effects on human kidney function are indicated by some measurements already at today's exposure levels. If food product
A method with low MDL (minimum detection limit) was developed for analysis of carbon (C), nitrogen (N) and oxygen (O) in aerosol samples collected on an organic backing. An accelerator-produced beam of protons interacting with the sample and the detection of elastically scattered protons (PESA; particle elastic scattering analysis) and emitted X-rays (PIXE; particle-induced X-ray emission) were th
In the reactione + e – rarrW + W – rarr ( $$q_1 ar q_2 $$ ) ( $$Q_1 ar Q_2 $$ ) we expect that normally the colour singlet systems ( $$q_1 ar q_2 $$ ) and ( $$Q_1 ar Q_2 $$ ) hadronize independently into two hadron chains or strings. However also the pairs ( $$q_1 ar Q_2 $$ ) and ( $$Q_1 ar q_2 $$ ) form colour singlets with probability 1/N c 2 =1/9. This probability could be further enhanced by g
Background. Partial correction of renal anaemia with erythropoietin improves quality of life (QoL). We aimed to examine if normalization of haemoglobin with epoetin alfa in pre-dialysis and dialysis patients further improves QoL and is safe. Methods. 416 Scandinavian patients with renal anaemia [pre-dialysis, haemodialysis (HD) and peritoneal dialysis patients] were randomized to reach a normal ha
Jag diskuterar i denna artikel popmusikens lyriska aspekter utifrån intertextualitetsbegreppet. I exemplet med Håkan Hellströms poptexter framträder tydligt intertextualiteten som funktion i betydelsproducerande strategier.
Ambivalence to treatment and repeated suicidal behaviour are well-known problems in suicide attempters. A randomised controlled study was performed to investigate the influence of repeated telephone contacts on treatment attendance, repetition of suicidal behaviour and mental health the year after a suicide attempt. SUBJECTS AND METHODS: One month after their suicide attempt 216 patients were rand
Abstract The contribution of biofilm and artificial feeds for the growth of the pink shrimp Farfantepenaeus paulensis reared in tanks and net cages were evaluated by using stable isotope (δ13C and δ15N) analysis. In the net cage experiment, mass balance and mixing equations showed that the biofilm contribution to shrimp growth was over 49% of carbon and 70% of nitrogen. These data suggest that the
PURPOSE: Hereditary prostate cancer accounts for 5% to 10% of all prostate cancer cases. We assessed clinical characteristics and survival in patients with hereditary prostate cancer MATERIALS AND METHODS: The study comprised 201 patients from 62 Swedish hereditary prostate cancer families and 402 controls with prostate cancer who were matched for age and calendar year at diagnosis, and the hospit
In a long-term and global perspective irrigated and terraced landscapes, landesque capital, have often been assumed to be closely associated with hierarchical political systems. However, research is accumulating that shows how kinship-based societies (including small chiefdoms) have also been responsible for constructing landesque capital without population pressure. We examine the political econo
Orbital-specific femtosecond charge transfer dynamics between Fe(II)-tetraphenylporphyrin molecules and semimetallic molybdenum disulfide substrates is investigated using core-level resonant photoemission spectroscopy. The electronic coupling to the substrate and the efficiency of charge transport across the interface is found to be different for the individual molecular electronic subsystems. In
