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Accelerating inference for diffusions observed with measurement error and large sample sizes using approximate Bayesian computation

In recent years, dynamical modelling has been provided with a range of breakthrough methods to perform exact Bayesian inference. However, it is often computationally unfeasible to apply exact statistical methodologies in the context of large data sets and complex models. This paper considers a nonlinear stochastic differential equation model observed with correlated measurement errors and an appli

Sociology of Law in a Digital Society - A Tweet from Global Bukowina

Is it possible to determine the Facebook Gemeinschaft or the living law of the global file sharing community? What are the social facts of twitter or the intuitive law of Chinese microbloggers? This paper argues that digitization of society, the reliance on digital networks, protocol, algorithms and completely new sets of organisational structures for social communities, have vast implications for

Construction of a Pre-Clinical High Resolution Tomographic Scintillation Camera System

We are constructing a High Resolution Tomographic Scintillation Camera System for small animal imaging. The system consists of a CsI(Tl) scintillator coupled to a military surplus image intensifier with a CCD camera focused on the output window. The system operates in photons counting mode and the spatial resolution is improved by centroid calculations for every photon interaction. The system can

Insomnia symptoms in elderly persons - assessment, associated factors and non-pharmacological nursing interventions

The aim of this thesis was to test a tool for assessing insomnia symptoms in elderly persons and to investigate late-life insomnia in terms of associated factors and evidence of non-pharmacological interventions in healthcare settings. Data were collected by means of a systematic literature search (Study I), questionnaires (Studies II-III), interviews and observations (Study IV). The results from

Debris entrainment by basal freeze-on and thrusting during the 1995-1998 surge of Kuannersuit Glacier on Disko Island, west Greenland

Kuannersuit Glacier, a valley glacier on Disko Island in west Greenland, experienced a major surge from 1995 to 1998 where the glacier advanced 10.5 km and produced a similar to 65 m thick stacked sequence of debris-rich basal ice and meteoric glacier ice. The aim of this study is to describe the tectonic evolution of large englacial thrusts and the processes of basal ice formation using a multipr

Fluid balance monitoring by cuff-occluded rate of rise of peripheral venous pressure in haemodialysis patients.

Cuff-occluded rate of rise of peripheral venous pressure has been proposed to reflect volume changes in experimental studies. The aim of this study was to evaluate changes in cuff-occluded rate of rise of peripheral venous pressure associated with fluid removal by haemodialysis in six adult patients with chronic renal failure on intermittent haemodialysis. Measurements were carried out before and

It Breaks a Man's Heart - Socioeconomic Differences in the Onset of Cardiovascular Disease in Contemporary Sweden

Popular Abstract in English This doctoral thesis investigates the onset of cardiovascular disease with a focus on socioeconomic differences as explanatory factors. Analyzing a contemporary population of natives and foreign-born individuals in Sweden, socioeconomic status is operationalized through a variety of measures. The importance of this study is found in the high cost of cardiovascular interThis doctoral thesis investigates the relationship between socioeconomic status and the onset of cardiovascular disease in a contemporary population of natives and foreign-born individuals in Sweden. The complexity of individual socioeconomic characteristics and the interrelationship with other cardiovascular risk factors is the focus of the studies in this thesis. As in most developed countries,

Modeling Diamond-Blackfan Anemia in the Mouse: Disease Pathogenesis and Evaluation of Novel Therapies

Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplasia that presents early in infancy. The main hematopoietic symptoms include macrocytic anemia with reticulocytopenia and selective absence of erythroid precursors in a normocellular bone marrow. In addition to the hematopoietic symptoms, DBA is characterized by the presence of physical abnormalities and cancer predisposition. Mutations

Service life of wood in outdoor above ground applications - engineering design guideline

This engineering design guideline is intended for wood in outdoor above ground applications, i.e. use class 3 according to EN 335. It is based on a prescribed limit state for onset of decay during a reference service life of 30 years. Onset of decay is defined as a state of fungal attack according to rating 1 in EN 252. The approach is to determine the climate exposure as a function of geographica

Design of bezel antennas for multiband MIMO terminals using characteristic modes

Designing decorrelated MIMO antennas in small mobile terminals at frequencies below 1 GHz is challenging since more than one antenna tend to excite the single resonant mode available to a typical chassis structure. This challenge increases even further when multiple frequency bands are required from each antenna. Recently, a design framework to obtain efficient and decorrelated MIMO antennas based

Jättelokan upprättad.

Det är dags att acceptera jättelokan i den svenska floran. Det anser botanikern Lars Fröberg. Växten har varit bannlyst i Sverige under mer än ett kvartssekel.

High Familial Risk of Atrial Fibrillation/Atrial Flutter in Multiplex Families: A Nationwide Family Study in Sweden

Background-Although the heritability of atrial fibrillation/atrial flutter (AF/AFl) has been determined, the familial risk in multiplex families is unclear. The main aim of this nationwide study was to determine the familial risk of AF/AFl in multiplex families. Methods and Results-We examined the familial risk of AF/AFl in the entire Swedish population. We linked Multigeneration Register data on

Urinary osteocalcin and other markers of bone metabolism: the effect of risedronate therapy

Objective. Serum osteocalcin (S-OC) is widely used as an index of bone formation. However, there is evidence that some urinary fragments of OC reflect resorption and might be useful in monitoring antiresorptive therapy. Here, we report 6-month changes in urinary midfragments of osteocalcin (U-MidOC) and other bone turnover markers in response to risedronate treatment. Material and methods. The stu

Breast Tomosynthesis or Digital Mammography for Breast Cancer Screening?

Screening mammography plays a key role in the early detection of breast cancer, however, estimates of sensitivities (48-88%) and specificities (82-98%) suggest that the diagnostic accuracy can be improved (1, 2, 3). Breast tomosynthesis (BT) is a 3D technique that is expected to improve breast cancer detection compared to screen-film and digital mammography DM). This work presents two clinical obs

Haemophilus influenzae Protein E Binds to the Extracellular Matrix by Concurrently Interacting With Laminin and Vitronectin

Nontypeable Haemophilus influenzae (NTHi) causes otitis media and is commonly found in patients with chronic obstructive pulmonary disease (COPD). Adhesins are important for bacterial attachment and colonization. Protein E (PE) is a recently characterized ubiquitous 16 kDa adhesin with vitronectin-binding capacity that results in increased survival in serum. In addition to PE, NTHi utilizes Haemop