Background: The construct of aggression is central to work with violent offenders, but it is a broad construct that can be assessed by many different methods and instruments. Its measurement may, however, have profound implications for treatment planning. We need more knowledge about how different methods for assessing aggression relate to each other. Aims: Our aims were to investigate, first, the

Analysis of the genomic landscape of prostate cancer has identified different molecular subgroups with relevance for novel or existing targeted therapies. The recent approvals of the poly(ADP-ribose) polymerase (PARP) inhibitors olaparib and rucaparib in the metastatic castration-resistant prostate cancer (mCRPC) setting signal the need to embed molecular diagnostics in the clinical pathway of pat

The security analysis of Keccak, the winner of SHA-3, has attracted considerable interest. Recently, some attention has been paid to the analysis of keyed modes of Keccak sponge function. As a notable example, the most efficient key recovery attacks on Keccak-MAC and Keyak were reported at EUROCRYPT’15 where cube attacks and cube-attack-like cryptanalysis have been applied. In this paper, we devel

The notion of corporate social responsibility (CSR) from the perspective of sustainability has been a part of the academic discussion in recent years. Different studies have also highlighted the inability of the SME sector to implement a CSR plan to achieve sustainability objectives. How-ever, why this sector is unable to adopt CSR is something that has not been properly attended by contemporary s

Large-scale genomic alterations play an important role in disease, gene expression, and chromosome evolution. Optical DNA mapping (ODM), commonly categorized into sparsely-labelled ODM and densely-labelled ODM, provides sequence-specific continuous intensity profiles (DNA barcodes) along single DNA molecules and is a technique well-suited for detecting such alterations. For sparsely-labelled barco

Railways operate in an open environment where temperature, humidity, and the oxidation conditions are subjected to change. An experimental investigation used a pin-on-disc machine to examine the influence of environmental conditions and iron oxides on the wear performance of the wheel-rail contact. The wear mechanisms were analyzed using scanning electron microscopy and found to be highly dependen

The effect of aluminum on microstructure and properties of martensitic wear-resistant and heat-resistant steels was investigated. The results indicate that as-cast microstructure of the specimens is composed of ferrite, pearlite and carbides. After quenching at 1,000 C and tempering at 600 C, the microstructure of the specimens consists of tempered sorbite and Fe-Cr-Al intermetallic compounds whic

We show that it is possible to induce a defined secondary structure in de novo designed peptides upon electrostatic attachment to negatively charged lipid bilayer vesicles without partitioning of the peptides into the membrane, and that the secondary structure can be varied via small changes in the primary amino acid sequence of the peptides. The peptides have a random-coil conformation in solutio

Cartilage oligomeric matrix protein (COMP) is a regulator of the extracellular matrix and is expressed primarily in the cartilage. Recently, COMP expression was also documented in breast cancer patients both in sera and tumor biopsies, in both of which it could serve as an independent prognostic marker. This study aimed to assess COMP as a potential biomarker in the group of metastatic breast canc

Objective: The aim of this study was to investigate long-term post-recurrence survival outcomes in young women receiving fertility-sparing surgery (FSS) to verify the feasibility of the limited surgery for epithelial ovarian cancer (OvCa). Study design: We performed a regional multicenter retrospective study from January 1986 and March 2020, using clinical data corrected under the central patholog

Background: Discrimination of heart failure with preserved ejection fraction with pulmonary hypertension (HFpEF-PH) from pulmonary arterial hypertension (PAH) is crucial for clinical management but may be challenging due to similarities in clinical and comorbid characteristics. We aimed to investigate tumour and metabolism related proteins in differentiating HFpEF-PH from PAH. Methods: Sixty-nine

Background: Transient tachypnea of the newborn (TTN) is caused by delayed clearance of lung fluid at birth. TTN typically appears within the first two hours of life in term and late preterm neonates and is characterized by tachypnea and signs of respiratory distress. Although it is usually a self-limited condition, admission to a neonatal unit is frequently required for monitoring and providing re

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the effects of pharmacological interventions for pain and sedation management in newborn infants undergoing therapeutic hypothermia.

Objective: To explore whether magnetic resonance imaging (MRI) features suggestive of knee osteoarthritis (OA) are associated with presence of knee pain in possible early-stage OA development. Methods: We included 294 participants from the Osteoarthritis Initiative (mean ± SD age 50 ± 3 years; 50% women) with baseline Kellgren/Lawrence grade of 0 in both knees, all of whom had received knee MRIs a