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PURPOSE: When central nervous system axons are injured, regeneration is partly inhibited by myelin-associated inhibitors (MAIs). Following traumatic brain injury (TBI) in the rat, pharmacological neutralisation of the MAIs Nogo-A and myelin-associated glycoprotein (MAG) resulted in improved functional outcome. In contrast, genetic or pharmacological neutralization of the MAI receptors Nogo-66 rece
Epidemiological evidence links severe or repeated traumatic brain injury (TBI) to the development of Alzheimer's disease (AD). Accumulation of amyloid precursor protein (APP) occurs with high frequency after TBI, particularly in injured axons, and APP may be cleaved to amyloid-β (Aβ) peptides playing key pathophysiological roles in AD. We used cerebral microdialysis (MD) to test the hypothesis tha
Superheavy element research relies heavily on the detection of correlated decay chains. When several chains have been detected, it is natural to ask whether they form one congruent set, or whether they should be further divided into subsets. To statistically assess the congruence between the chains in a data set, we developed a procedure to calculate a Figure-of-Merit for low-number statistics. In
The fission process still remains a main factor that determines the stability of the atomic nucleus of heaviest elements. Fission half-lives vary over a wide range, 10^−19 to 10^24 s. Present experimental techniques for the synthesis of the superheavy elements that usually measure α-decay chains are sensitive only in a limited range of half-lives, often 10^5 to 10^3 s. In the past years, measureme
Phosphopeptides are often detected with low efficiency by MALDI MS analysis of peptide mixtures. In an effort to improve the phosphopeptide ion response in MALDI MS, we investigated the effects of adding low concentrations of organic and inorganic acids during peptide sample preparation in 2,5-dihydroxybenzoic acid (2,5-DHB) matrix. Phosphoric acid in combination with 2,5-DHB matrix significantly
This study examines the rise and fall of the modern Belarusian national movement during the quarter century between 1906, the year when the first Belarusian paper appeared, until its demise around 1931, as a result of political repression in the Soviet Union and Poland. It surveys the emergence of the modern concept of a Belarusian nation, from the first steps towards national consolidation in the
Clean gas turbine combustion research has gained popularity in power generation and propulsion industry in recent days. Present days, advanced efficient emission (NOx, CO and UHC) reduction combustion technologies are acknowledged for using the lean premixed combustion system. To support continuous development of eco-friendly combustion system, a 4th generation dry low NOx prototype downscaled bur
Many injection drug users are infected with hepatitis C virus (HCV), yet few are treated. With opiate maintenance treatment, expected life length increases, and the incitement increases to treat HCV in order to avoid long term complications. The aim of the present study was to investigate attitudes towards HCV and HCV treatment willingness among opiate-dependent injection drug users at Malmö needl
This paper is about the ways in which financialisation of built environments hasimpacted upon the politics, social constitution and sustainability of cities. We focus primarily on financialisation of housing, and do so from the methodologicalperspective of variegated financialisation: as a generic process that contextually coevolves with related processes such as neoliberalisation and polarisation
We study the structural dynamics of photoexcited [Co(terpy)2]2+ in an aqueous solution with ultrafast x-ray diffuse scattering experiments conducted at the Linac Coherent Light Source. Through direct comparisons with density functional theory calculations, our analysis shows that the photoexcitation event leads to elongation of the Co-N bonds, followed by coherent Co-N bond length oscillations ari
