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PURPOSES: To describe the differential tissue expression of tumor-associated trypsin inhibitor (TATI) in normal bladder urothelium, primary urothelial carcinoma of the bladder (UCB) and metastatic UCB and to assess the association of TATI expression with molecular markers commonly altered in UCB and clinical outcomes after radical cystectomy. METHODS: Slides from eight cystectomy patients without
This thesis is concerned with the ways in which justice is dispensed in Swedish courts in cases concerning anti-Muslim violence. Based on material accessed through the Swedish National Board for Crime Prevention and classified as Islamophobic hate crimes, the judicial treatment of cases that may involve racism is analysed. An aim is to explore how different laws against racism in the Swedish legal
OBJECTIVE: The aims of this study were: to follow the course of recovery of motor function following acute stroke, as assessed by the Physiotherapy Clinical Outcome Variables Scale (COVS), and; to investigate the ability of this instrument to predict length of hospital stay, discharge destination and future home facility. METHODS: In this prospective longitudinal study, COVS was registered at admi
We study the problem of detecting and localizing objects that are embedded in compressed video sequences. Such a capability has two major and increasingly important practical uses: (1) video surveillance; (2) identification of copyright infringement. We focus here only on the problem of video surveillance. As a general rule, detection and localization of patterns is most efficiently performed in a
This paper argues that Person interprets event participants in relation to speech participants in a parallel fashion as grammatical Tense interprets event time in relation to speech time. This understanding of Person is embedded in a general theory of speech-grammar-event matching, that is to say, an approach where speech (event) features, SF, are matched by grammatical features, GF, which in turn
Aims Genetic testing is needed for the formal diagnosis of maturity-onset diabetes of the young (MODY), but this is not widely available. If any MODY biomarkers were known, these could possibly be used as an alternative. Hepatocyte nuclear factor (HNF)-1alpha and HNF-4alpha regulate transcription of genes encoding complement 5 (C5), complement 8 (C8) and transthyretin (TTR), suggesting that these
Objectives. Human leucocyte antigens (HLAs) are polymorphic molecules involved in antigen presentation. Associations between HLA type and autoimmune diseases, such as type 1 diabetes and rheumatoid arthritis, are well established but the potential association of genetic variation affecting antigen presentation with cardiovascular disease has not been systematically investigated in large cohorts. T
Summary The CAG repeat in the androgen receptor (AR) has been widely studied in association with male infertility, but the results are conflicting. In a recent meta-analysis, infertile men had <1 repeat longer CAG stretch than fertile men when analysed in a linear regression model assuming that AR function diminishes with increasing CAG length. However, in vitro, a non-linear activity pattern was
STUDY OBJECTIVES: To calculate incremental cost-utility ratios (cost per QALY gained) for varenicline (Champix; Pfizer), as compared to bupropion, in smoking-cessation programmes for a lifetime follow-up period. DESIGN: The Benefits of Smoking Cessation on Outcomes (BENESCO) simulation model was used for a male and female cohort, respectively, as a point of departure but further extended in order
OBJECTIVE: To assess the reliability of knee extensor and flexor muscle strength measurements in persons with late effects of polio. DESIGN: A test-retest reliability study. SUBJECTS: Thirty men and women (mean age 63 (standard deviation 6.4) years) with verified late effects of polio. METHODS: Knee extensor and flexor muscle strength in both lower limbs were measured twice 7 days apart using a Bi
Aims: Skeletal muscle is a major metabolic organ and plays important roles in glucose metabolism, insulin sensitivity and insulin action. Muscle telomere length reflects the myocyte's exposure to harmful environmental factors. Leukocyte telomere length is considered a marker of muscle telomere length and is used in epidemiologic studies to assess associations with ageing-related diseases where mus
