An augmented version of the traditional relay feedback experiment is proposed. It aims at producing an input with energy concentrated to a frequency band, corresponding to a certain phase sector of the Nyquist curve of the process to be identified. A non-convex problem is formulated. Sub-optimal, but efficient, algorithms are developed.

Relapse is a major problem in acute myeloid leukemia (AML) and adversely affects survival. In this phase 2 study, we investigated the effect of vaccination with dendritic cells (DCs) electroporated with Wilms’ tumor 1 (WT1) messenger RNA (mRNA) as postremission treatment in 30 patients with AML at very high risk of relapse. There was a demonstrable antileukemic response in 13 patients. Nine patien

Chemosignals are used by predators to localize prey and by prey to avoid predators. These cues vary between species, but the odor of blood seems to be an exception and suggests the presence of an evolutionarily conserved chemosensory cue within the blood odor mixture. A blood odor component, E2D, has been shown to trigger approach responses identical to those triggered by the full blood odor in ma

Background: Quality of supervision is a major predictor for successful PhD projects. A survey showed that almost all PhD students in the Health Sciences in Denmark indicated that good supervision was important for the completion of their PhD study. Interestingly, approximately half of the students who withdrew from their program had experienced insufficient supervision. This led the Research Educa

Despite of a crucial role of microclimate inside clothing in thermal comfort, air velocity inside clothing has been hardly reported, ever since Lewis et al (1969) demonstrated that air velocity of the still air layer on the naked human body was 0.25 m/s using colour schlieren cinephotography. This study was aimed to investigate the air velocity of microenvironment inside clothing and the bellows e

BACKGROUND AND PURPOSE: There are, to date, no MR imaging diagnostic markers for Lewy body dementia. Nigrosome 1, containing dopaminergic cells, in the substantia nigra pars compacta is hyperintense on SWI and has been called the swallow tail sign, disappearing with Parkinson disease. We aimed to study the swallow tail sign and its clinical applicability in Lewy body dementia and hypothesized that

An investigation with respect to inhibition of nitrification of wastewater from 109 Swedish municipal wastewater treatment plants was performed. Flow proportional, 24-hour composite samples were collected during one week, and then analysed using the screening method. Inhibition of nitrification above 10% was found at only 20 plants. In general, the load of inhibiting substances is limited in Swedi

The small molecule inhibitor acetazolamide (AZM) was conjugated to a set of designed polypeptides and the resulting conjugates were evaluated for their affinity to Human Carbonic Anhydrase II (HCA II) using surface plasmon resonance. The dissociation constant of the AZM-HCA II complex was 38. nM and that of the AZM conjugated polypeptide (4-C10L17-AZM) to HCA II was found to be 4. nM, an affinity

The energy hub concept is gradually getting popular due to its capability to integrate renewable energy technologies into the energy grid with a minimum impact. Designing distributed energy hubs is a challenging task due to the coupling of optimum dispatch and energy system sizing problems. Operation of the system needs to be considered for 8760 time steps and energy system sizing optimization can

Background: C-X-C motif chemokine ligand 8 (CXCL8) is a multi-functional chemokine and has important roles during tumor formation and development. It was previously reported that increased CXCL8 protein levels occurred in certain patients. Materials and Methods: In the present study, we examined levels of CXCL8 mRNA in breast cancer tissues and analyzed its levels in correlation to patients' clini