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We have monitored the composition of supported phospholipid bilayers during phospholipase A(2) hydrolysis using specular neutron reflection and ellipsometry. Porcine pancreatic PLA(2) shows along lag phase of several hours during which the enzyme binds to the bilayer surface, but only 5 +/- 3% of the lipids react before the onset of rapid hydrolysis. The amount of PLA(2), which resides in a 21 +/-
It is demonstrated that photographic images of plants can be produced in the absence of external illumination using an image intensifier. The image is produced by the weak delayed light emission (afterglow) from photosynthetically active chloroplasts. The use of such phytoluminographs is proposed for the study and diagnosis at an early stage of disturbances due to parasites, mineral deficiency, he
PHENIX has measured the centrality dependence of midrapidity pion, kaon, and proton transverse momentum distributions in d+Au and p+p collisions at root s(NN) = 200 GeV. The p+p data provide a reference for nuclear effects in d+Au and previously measured Au+Au collisions. Hadron production is enhanced in d+Au, relative to independent nucleon-nucleon scattering, as was observed in lower energy coll
Activation of AMP-activated protein kinase (AMPK) by exercise and metformin is beneficial for the treatment of type 2 diabetes. We recently found that, in cultured cells, the LKB1 tumor suppressor protein kinase activates AMPK in response to the metformin analog phenformin and the AMP mimetic drug 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR). We have also reported that LKB1 activ
Mouse models of asthma are now being used extensively in drug research. However, the successful unravelling of combinatorial interplays of cells and molecules in the murine airways may not be matched by equally successful demonstrations of an asthma-like pathophysiology. Here, Carl Persson, Jonas Erjefalt, Magnus Korsgren and Frank Sundler discuss the fact that major features of asthma may still n
We show that the distance densities that can arise from a many-body wavefunction (i.e., are N-representable) lie in a convex set. We show that the N-representable distance densities have positive Fourier transforms.
Abstract The aim of this study was to evaluate a general school-based 1-year exercise intervention program in a population-based cohort of girls at Tanner stage I. Fifty-three girls aged 7–9 years were included. The school curriculum-based exercise intervention program included 40 minutes/school day. Fifty healthy age-matched girls assigned to the general school curriculum of 60 minutes physical a
OBJECTIVE: To analyse the outcome of selective management of patients with abdominal aortic aneurysms, the expansion patterns of the aneurysms, and the factors that influenced the rate of rupture. DESIGN: Retrospective study. SETTING: Malmo General Hospital, Lund University, Malmo, Sweden. SUBJECTS: 155 patients (96 men and 59 women) with abdominal aortic aneurysms who were not selected for operat
We report the isolation and partial genetic characterization of two equine strains of granulocytic Ehrlichia of the genogroup Ehrlichia phagocytophila. Frozen whole-blood samples from two Swedish horses with laboratory-verified granulocytic ehrlichiosis were inoculated into HL-60 cell cultures. Granulocytic Ehrlichia was isolated and propagated from both horses. DNA extracts from the respective st
The objectives of this study were to report our experience with the laparoscopic video-assisted gastrostomy technique in infants operated during their first year of life. A total of 53 infants (35 males, 18 females) aged 6 +/- 3 months, varying from 3 weeks to 11 months, underwent video-assisted gastrostomy. They were prospectively followed up. Included are infants with neurological dysfunction, c
AIM: Non-participation in health surveys is a common phenomenon. When differences between participants and non-participants are considerable, the external validity of the sample survey may decrease and false conclusions might be drawn about the health status of the population. For this reason, the authors aimed to investigate the representativity of a postal questionnaire survey performed in the c
The crystal structures of the following calcium sulfate phases are reviewed: CaSO4.2H(2)O (C (S) over barH(0.5), monoclinic); CaSO4.0.6H(2)O (C (S) over barH(0.6), pseudotrigonal, monoclinic); CaSO4.0.5H(2)O (C (S) over barH(0.5), monoclinic); CaSO4 (111, CS, pseudohexagonal, orthorhombic), CaSO4 (II, CS, orthorhombic). Drawings of the atomic structures, crystal data and literature references are
Malignant hyperthermia (MH), a potentially lethal disorder of skeletal muscle calcium homeostasis, manifests only on exposure to certain anaesthetic drugs. The mode of inheritance appears to be autosomal dominant with both locus and allelic heterogeneity having been reported. Association analysis of eight MH candidate loci in UK families has indicated that several genes influence susceptibility in
This report investigates replacing chloride salts with calcium magnesium acetate (CMA) for use as de-icers.
