Search results

Filter

Filetype

Your search for "*" yielded 535172 hits

Long-term exposure to residential transportation noise and mortality : A nationwide cohort study

Studies have indicated that transportation noise is associated with higher cardiovascular mortality, whereas evidence of noise as a risk factor for respiratory and cancer mortality is scarce and inconclusive. Also, knowledge on effects of low-level noise on mortality is very limited. We aimed to investigate associations between road and railway noise and natural-cause and cause-specific mortality

ON KANNAN-GERAGHTY MAPS AS AN EXTENSION OF KANNAN MAPS

Extending the concept of weakly Kannan maps on metric spaces, we study the maps as $f:X\rightarrow X$ on a metric space $(X, d)$ satisfying condition $d(f(x), f(y)) \leq (1/2)\beta(d(x, y))[d(x ,f(x)) + d(y, f(y))]$ for every $x, y\in X$ and a function $\beta: [0, \infty)\rightarrow [0,1)$ where for every sequence $t=\{t_n\}$ of non-negative real numbers satisfying $\beta(t_n)\rightarrow 1,$ while

An inflamed subtype of difficult-to-treat depression

BACKGROUND: Chronic low-grade inflammation may play a role in the pathophysiology of depression, at least in a subset of patients. High-sensitivity C-reactive protein (hs-CRP) has been used to define an inflamed subgroup of depression with specific clinical characteristics and symptoms. In this study we investigated biochemical and clinical characteristics in patients with difficult-to-treat depre

Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis

WW domain binding protein 1-like (WBP1L), also known as outcome predictor of acute leukaemia 1 (OPAL1), is a transmembrane adaptor protein, expression of which correlates with ETV6-RUNX1 (t(12;21)(p13;q22)) translocation and favourable prognosis in childhood leukaemia. It has a broad expression pattern in haematopoietic and in non-haematopoietic cells. However, its physiological function has been

Boron Cage Triggered Micellization of a Neutral–Cationic Block Copolymer and Preparation of Boron-Containing Layer-by-Layer Microparticles

The preparation of a polymer carrier for a boron delivery agent is presented through a combination of experimental and computational studies. A dodecahydro-closo-dodecaborate (B12H12)2– (B12) anion was used as a model boron-containing agent due to its high boron content. Quaternized poly(2-vinyl pyridine)-b-poly(ethylene oxide) (QP2VP-b-PEO) was chosen as a model neutral–cationic block copolymer t

Cave odours as possible destination cues in the long-distance navigation of the Australian Bogong moth Agrotis infusa

Kan Bogong fjärilar dofta sig till en säker plats? Att komma hem från en lång semester och lägger sig i sin egen säng, känna doften av ens egna kudde och lägenhet ger en känsla av säkerhet. Det är en doft av hemma, av trygghet som vi känner igen. Är det möjligt att få samma upplevelse med en doft man aldrig känt förut? Så kan det vara för Bogong fjärilen (Agrotis infusa). De är nattaktiva fjärilaThe Bogong moth Agrotis infusa is a long-distance nocturnal migrant whose navigational ability still remains only partly understood. They travel up to a thousand kilometres to the Australian Alps where they seek out the shelter of isolated cool alpine caves, thereby escaping the approaching summer heat of their breeding grounds. Once in the caves, they enter a state of dormancy over the coming sum

Self-supervised representation learning from electrocardiogram data for medical applications

Cardiovascular diseases are the leading cause of death worldwide, increasing yearly. However, many abnormalities in heart cycles can be discovered and treated years before the onset of diseases. But in most societies, regular health checkups are a concept reserved for cars, not humans. In order to save lives, our healthcare systems must adopt a preventative rather than a reactive approach. To that

Effective communications on invasive alien species : Identifying communication needs of Swedish domestic garden owners

Invasive alien species threaten biodiversity with domestic gardens acting as a major pathway for the introduction of alien species. Even though the Nordic region is not currently a hotspot for biological invasions, the number of invasions in the Nordic area has been predicted to increase due to climate change. Given a time lag between introduction and invasion, many non-invasive horticultural alie

Identification of biomarkers for glycaemic deterioration in type 2 diabetes

We identify biomarkers for disease progression in three type 2 diabetes cohorts encompassing 2,973 individuals across three molecular classes, metabolites, lipids and proteins. Homocitrulline, isoleucine and 2-aminoadipic acid, eight triacylglycerol species, and lowered sphingomyelin 42:2;2 levels are predictive of faster progression towards insulin requirement. Of ~1,300 proteins examined in two

Tru-Cut Biopsy in Gynecological Cancer: Adequacy, Accuracy, Safety and Clinical Applicability

Purpose: Tru-cut biopsy is a minimally invasive technique used to obtain tissue samples for the diagnosis of tumors, especially in patients where primary surgery is not indicated. The aim of this study was to assess the adequacy, accuracy and safety of the tru-cut biopsy for diagnosis in gynecological cancer.Methods: A retrospective population-based review of 328 biopsies was conducted. The indica

Probitfunktioner – En studie av tillämpning i Sverige och effekter av förändrade probitkonstanter

The purpose of this thesis was to investigate how probit functions have changed based on research that has been conducted by RIVM in the Netherlands, and to investigate how the calculated risk evaluation changes when using new values derived in QRAs conducted in Sweden. The goal was to quantify any differences that might occur due to the changes in probit functions. To conduct this thesis a survey

Physical Activity and the Development of Islet Autoimmunity and Type 1 Diabetes in 5-15-Year-Old Children Followed in the TEDDY Study

OBJECTIVE: This study investigated physical activity and its association with the development of islet autoimmunity and type 1 diabetes in genetically at-risk children aged 5-15 years.RESEARCH DESIGN AND METHODS: As part of the longitudinal Environmental Determinants of Diabetes in the Young (TEDDY) study, annual assessment of activity using accelerometry was conducted from age 5 years. Time-to-ev

Treatment with mycophenolate mofetil is associated with improved nailfold vasculature in systemic sclerosis

OBJECTIVE: To investigate the evolution of nailfold capillary density in patients with systemic sclerosis (SSc) in relation to immunosupressive treatment and autoantibodies.METHODS: Prospective study cohort. Consecutive newly diagnosed SSc patients were included into this study who, in a retrospective review, had at least 2 nailfold capillary microscopy (NCM) measurements performed during the firs

Infrared Photodetectors based on InSb and InAs Nanostructures via Heterogeneous Integration-Rapid Melt Growth and Template Assisted Selective Epitaxy

Monolithic heterogeneous integration of III-V semiconductors with the contemporary Si Complementary Metal Oxide Semiconductor (CMOS) technology has instigated a wide range of possibilities and functionalities in the semiconductor industry, in the field of digital circuits, optical sensors, light emitters, and high-frequency communication devices. However, the integration of III-V semiconductors is