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Spreading of Localized Information across an Entire 3D Electrical Resistivity Volume via Constrained EMI Inversion Based on a Realistic Prior Distribution

Frequency-domain electromagnetic induction (EMI) methods are commonly used to map vast areas quickly and with minimum logistical efforts. Unfortunately, they are often characterized by a very limited number of frequencies and severe ill-posedness. On the other hand, electrical resistivity tomography (ERT) approaches are usually considered more reliable; for example, they do not require specific ca

Unleashing Ascl1 : Exploring Cross-Lineage Potential in Reprogramming and Regenerative Frontiers

In the era of stem cell research and regenerative medicine, understanding the regulatory networks that drive cellular reprogramming is fundamental. The study entitled ‘‘Cross-lineage potential of Ascl1 uncovered by comparing diverse reprogramming regulatomes’’ published in Stem Cell Reports sheds light on the remarkable versatility of Ascl1, a transcription factor known for its pivotal role in neu

The Imperative of Crisis : Power, Knowledge and Action in the Swedish Crisis Management System

This thesis investigates Swedish crisis management. This thesis aims to contribute to crisis research by providing critical perspectives on the role of knowledge in crisis management settings. The papers in this thesis stem from empirical studies of the major cases of Swedish crisis management during the last decade, including the Swedish refugee crisis in 2015, the wildfires in 2018, and the Covi

Understanding how endothelial cells affect necrotizing soft tissue infections using an in vitro organotypic soft tissue infection model

Köttätande bakterier – från ofarlig till livshotande Bakterier är små levande ting som inte är synliga för blotta ögat. Alla bakterier orsakar inte sjukdom och vissa bakterier gör det om de befinner sig på fel plats i din kropp. Köttätande bakterier har fått sitt namn från att dom gör att vävnad i kroppen dör och när det sker orsakar dessa bakterier en mycket sällsynt och livshotande infektion. I

Primary and hTERT-Transduced Mesothelioma-Associated Fibroblasts but Not Primary or hTERT-Transduced Mesothelial Cells Stimulate Growth of Human Mesothelioma Cells

Pleural mesothelioma (PM) is an aggressive malignancy that develops in a unique tumor microenvironment (TME). However, cell models for studying the TME in PM are still limited. Here, we have generated and characterized novel human telomerase reverse transcriptase (hTERT)-transduced mesothelial cell and mesothelioma-associated fibroblast (Meso-CAF) models and investigated their impact on PM cell gr

On the crystal structure of small gold crystals and large gold clusters

A large gold cluster with the formula Au55[(C6H5)3P]12Cl6, was imaged with a high-resolution transmission electron microscope (HRTEM) and a proposed model was confirmed. Growth of gold crystals of approximately 4.0 nm size could be followed, row by row of atoms, with the use of a low light level TV camera and on-line image processing.

Krishantering, beredskap och lärdomar av tsunamifallen vid Indiska Oceanen 2004 & Japan 2011 Förebyggande åtgärder för människor och bebyggelse

Krishantering och förebyggande arbete inför naturkatastrofer, som i detta examensarbete avgränsas till tsunamis, har identifierats som bristande genom tiderna. Här studeras tsunamikatastroferna i Indiska Oceanen 2004 och Japan 2011 för att identifiera brister hos varningssystemen som används för att skydda samhällena som befinner sig i dessa riskzoner och dess befolkning. Först visade det sig att

Collective Horizons: Rethinking the performative and the political (im)possibilities of being together

Invisible Committee, ‘the name given to a collective voice bent on denouncing contemporary cynicism and reality’ (described by one of the members of the anonymous group), published a text in 2007 that hypothesised the ‘imminent collapse of capitalist culture’ that would arise from new waves of social contestation. Under the title The Coming Insurrection the text (denounced as a manual for terroris

Risks of alcohol and drug use disorders in prostate cancer survivors : a national cohort study

Background: Prostate cancer (PC) survivors may potentially use substances to cope with psychological distress or poorly controlled physical symptoms. Little is known, however, about the long-term risks of alcohol use disorder (AUD) or drug use disorders in men with PC. Methods: A national cohort study was conducted in Sweden of 180-189 men diagnosed with PC between 1998 and 2017 and 1 801 890 age-

Ruptured Stages and the Dramaturgies of Debt and Time

About the book:Fourteen scholars who work on campus or in the theater address this issue of what it means to play offstage. With their individual definition of what “offstage” could mean, the results were, predictably, varied. They employed a variety of critical approaches to the question of what happens when the play moves into the audience or beyond the physical playhouse itself? What are the so

Exploring the knowledge contributions of carers involved in a group process aimed at co-creating a targeted support intervention

Patient and public involvement is a way of ensuring that research and practices are more responsive to their target groups. This study, inspired by discourse psychology, explores the knowledge contributions of informal carers who participated in group meetings to co-create a support intervention. Findings highlight that carers’ knowledge is complex, including more than practical caring experiences

Dislocating Institutions: Theses/Momentums of (Un)Making Spaces of Culture

Cultural and academic institutions have been in crisis for quite some time now. In many cases, they still refer to a canon that has been made obsolete by global developments – in particular, by new voices from the Global South. Their modes of knowledge production operate within disciplinary bounds that can no longer cope with the Anthropocene’s radical processes of change, and their self-referenti

Trump, Clinton, and the gendering of newspaper discourse about the 2016 US presidential election debates

Electoral politics remains a much-gendered sphere, dominated by men political actors and masculine behaviors. Media coverage of politics has often reinforced gendered norms. This article uses qualitative thematic analysis of three U.S. newspapers’ coverage of the 2016 presidential debates between Donald Trump and Hillary Clinton to explore how the mediated construction of political leaders is gend

Vector autoregression : Useful in rare diseases?—Predicting organ response patterns in a rare case of secondary AA amyloidosis

Background Statistical analyses of clinical data are a cornerstone in understanding pathomechanisms of disorders. In rare disorders, cross-sectional datasets of sufficient size are usually not available. Taking AA amyloidosis as an example of a life-threatening rare disorder resulting from of uncontrolled chronic inflammation, we propose techniques from time series analysis to predict organ respon

Electromobility Impact on the Power Grid - Base Case for Probabilistic Modelling

The Swedish electric vehicle fleet is rapidly growing, creating a need to include their charging demand in future grid planning. Charging stations are often placed based on the needs of the transport system, and the grid connection is considered at a later stage with long lead times. This study proposes selecting charging locations based on grid capacity. Doing this by probabilistic load flow requ